F8A1

Coagulation factor VIII-associated (intronic transcript) 1, also known as F8A1, is a human gene.cite web | title = Entrez Gene: F8A1 coagulation factor VIII-associated (intronic transcript) 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=8263| accessdate = ]

PBB_Summary
section_title =
summary_text = This gene is contained entirely within intron 22 of the factor VIII gene; spans less than 2 kb, and is transcribed in the direction opposite of factor VIII. A portion of intron 22 (int22h), containing F8A, is repeated twice extragenically closer to the Xq telomere. Although its function is unknown, the observation that this gene is conserved in the mouse implies it has some function. Unlike factor VIII, this gene is transcribed abundantly in a wide variety of cell types.cite web | title = Entrez Gene: F8A1 coagulation factor VIII-associated (intronic transcript) 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=8263| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Levinson B, Kenwrick S, Gamel P, "et al." |title=Evidence for a third transcript from the human factor VIII gene. |journal=Genomics |volume=14 |issue= 3 |pages= 585–9 |year= 1992 |pmid= 1427887 |doi=
*cite journal | author=Levinson B, Bermingham JR, Metzenberg A, "et al." |title=Sequence of the human factor VIII-associated gene is conserved in mouse. |journal=Genomics |volume=13 |issue= 3 |pages= 862–5 |year= 1992 |pmid= 1639415 |doi=
*cite journal | author=Levinson B, Kenwrick S, Lakich D, "et al." |title=A transcribed gene in an intron of the human factor VIII gene. |journal=Genomics |volume=7 |issue= 1 |pages= 1–11 |year= 1990 |pmid= 2110545 |doi=
*cite journal | author=Naylor JA, Buck D, Green P, "et al." |title=Investigation of the factor VIII intron 22 repeated region (int22h) and the associated inversion junctions. |journal=Hum. Mol. Genet. |volume=4 |issue= 7 |pages= 1217–24 |year= 1996 |pmid= 8528212 |doi=
*cite journal | author=Peters MF, Ross CA |title=Isolation of a 40-kDa Huntingtin-associated protein. |journal=J. Biol. Chem. |volume=276 |issue= 5 |pages= 3188–94 |year= 2001 |pmid= 11035034 |doi= 10.1074/jbc.M008099200
*cite journal | author=Hartley JL, Temple GF, Brasch MA |title=DNA cloning using in vitro site-specific recombination. |journal=Genome Res. |volume=10 |issue= 11 |pages= 1788–95 |year= 2001 |pmid= 11076863 |doi=
*cite journal | author=Simpson JC, Wellenreuther R, Poustka A, "et al." |title=Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing. |journal=EMBO Rep. |volume=1 |issue= 3 |pages= 287–92 |year= 2001 |pmid= 11256614 |doi= 10.1093/embo-reports/kvd058
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Jenkins PV, Dill JL, Zhou Q, Fay PJ |title=Clustered basic residues within segment 484-510 of the factor VIIIa A2 subunit contribute to the catalytic efficiency for factor Xa generation. |journal=J. Thromb. Haemost. |volume=2 |issue= 3 |pages= 452–8 |year= 2004 |pmid= 15009463 |doi=
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Wiemann S, Arlt D, Huber W, "et al." |title=From ORFeome to biology: a functional genomics pipeline. |journal=Genome Res. |volume=14 |issue= 10B |pages= 2136–44 |year= 2004 |pmid= 15489336 |doi= 10.1101/gr.2576704
*cite journal | author=Bagnall RD, Ayres KL, Green PM, Giannelli F |title=Gene conversion and evolution of Xq28 duplicons involved in recurring inversions causing severe hemophilia A. |journal=Genome Res. |volume=15 |issue= 2 |pages= 214–23 |year= 2005 |pmid= 15687285 |doi= 10.1101/gr.2946205
*cite journal | author=Mehrle A, Rosenfelder H, Schupp I, "et al." |title=The LIFEdb database in 2006. |journal=Nucleic Acids Res. |volume=34 |issue= Database issue |pages= D415–8 |year= 2006 |pmid= 16381901 |doi= 10.1093/nar/gkj139
*cite journal | author=Brown V, Brown RA, Ozinsky A, "et al." |title=Binding specificity of Toll-like receptor cytoplasmic domains. |journal=Eur. J. Immunol. |volume=36 |issue= 3 |pages= 742–53 |year= 2006 |pmid= 16482509 |doi= 10.1002/eji.200535158
*cite journal | author=Parker ET, Doering CB, Lollar P |title=A1 subunit-mediated regulation of thrombin-activated factor VIII A2 subunit dissociation. |journal=J. Biol. Chem. |volume=281 |issue= 20 |pages= 13922–30 |year= 2006 |pmid= 16513639 |doi= 10.1074/jbc.M513124200

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