TADA2L

Transcriptional adaptor 2 (ADA2 homolog, yeast)-like, also known as TADA2L, is a human gene.cite web | title = Entrez Gene: TADA2L transcriptional adaptor 2 (ADA2 homolog, yeast)-like| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=6871| accessdate = ]

PBB_Summary
section_title =
summary_text = Many DNA-binding transcriptional activator proteins enhance the initiation rate of RNA polymerase II-mediated gene transcription by interacting functionally with the general transcription machinery bound at the basal promoter. Adaptor proteins are usually required for this activation, possibly to acetylate and destabilize nucleosomes, thereby relieving chromatin constraints at the promoter. The protein encoded by this gene is a transcriptional activator adaptor and has been found to be part of the PCAF histone acetylase complex. Two transcript variants encoding different isoforms have been identified for this gene.cite web | title = Entrez Gene: TADA2L transcriptional adaptor 2 (ADA2 homolog, yeast)-like| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=6871| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Maruyama K, Sugano S |title=Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides. |journal=Gene |volume=138 |issue= 1-2 |pages= 171–4 |year= 1994 |pmid= 8125298 |doi=
*cite journal | author=Candau R, Moore PA, Wang L, "et al." |title=Identification of human proteins functionally conserved with the yeast putative adaptors ADA2 and GCN5. |journal=Mol. Cell. Biol. |volume=16 |issue= 2 |pages= 593–602 |year= 1996 |pmid= 8552087 |doi=
*cite journal | author=Wang L, Mizzen C, Ying C, "et al." |title=Histone acetyltransferase activity is conserved between yeast and human GCN5 and is required for complementation of growth and transcriptional activation. |journal=Mol. Cell. Biol. |volume=17 |issue= 1 |pages= 519–27 |year= 1997 |pmid= 8972232 |doi=
*cite journal | author=Carter KC, Wang L, Shell BK, "et al." |title=The human transcriptional adaptor genes TADA2L and GCN5L2 colocalize to chromosome 17q12-q21 and display a similar tissue expression pattern. |journal=Genomics |volume=40 |issue= 3 |pages= 497–500 |year= 1997 |pmid= 9073520 |doi= 10.1006/geno.1996.4605
*cite journal | author=Henriksson A, Almlöf T, Ford J, "et al." |title=Role of the Ada adaptor complex in gene activation by the glucocorticoid receptor. |journal=Mol. Cell. Biol. |volume=17 |issue= 6 |pages= 3065–73 |year= 1997 |pmid= 9154805 |doi=
*cite journal | author=Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, "et al." |title=Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library. |journal=Gene |volume=200 |issue= 1-2 |pages= 149–56 |year= 1997 |pmid= 9373149 |doi=
*cite journal | author=Ogryzko VV, Kotani T, Zhang X, "et al." |title=Histone-like TAFs within the PCAF histone acetylase complex. |journal=Cell |volume=94 |issue= 1 |pages= 35–44 |year= 1998 |pmid= 9674425 |doi=
*cite journal | author=Vassilev A, Yamauchi J, Kotani T, "et al." |title=The 400 kDa subunit of the PCAF histone acetylase complex belongs to the ATM superfamily. |journal=Mol. Cell |volume=2 |issue= 6 |pages= 869–75 |year= 1999 |pmid= 9885574 |doi=
*cite journal | author=Wang T, Kobayashi T, Takimoto R, "et al." |title=hADA3 is required for p53 activity. |journal=EMBO J. |volume=20 |issue= 22 |pages= 6404–13 |year= 2002 |pmid= 11707411 |doi= 10.1093/emboj/20.22.6404
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Barlev NA, Emelyanov AV, Castagnino P, "et al." |title=A novel human Ada2 homologue functions with Gcn5 or Brg1 to coactivate transcription. |journal=Mol. Cell. Biol. |volume=23 |issue= 19 |pages= 6944–57 |year= 2003 |pmid= 12972612 |doi=
*cite journal | author=Ota T, Suzuki Y, Nishikawa T, "et al." |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Rual JF, Venkatesan K, Hao T, "et al." |title=Towards a proteome-scale map of the human protein-protein interaction network. |journal=Nature |volume=437 |issue= 7062 |pages= 1173–8 |year= 2005 |pmid= 16189514 |doi= 10.1038/nature04209
*cite journal | author=Qian C, Zhang Q, Li S, "et al." |title=Structure and chromosomal DNA binding of the SWIRM domain. |journal=Nat. Struct. Mol. Biol. |volume=12 |issue= 12 |pages= 1078–85 |year= 2006 |pmid= 16299514 |doi= 10.1038/nsmb1022

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