SFRP4

Secreted frizzled-related protein 4, also known as SFRP4, is a human gene.cite web | title = Entrez Gene: SFRP4 secreted frizzled-related protein 4| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=6424| accessdate = ]

PBB_Summary
section_title =
summary_text = Secreted frizzled-related protein 4 (SFRP4) is a member of the SFRP family that contains a cysteine-rich domain homologous to the putative Wnt-binding site of Frizzled proteins. SFRPs act as soluble modulators of Wnt signaling. The expression of SFRP4 in ventricular myocardium correlates with apoptosis related gene expression.cite web | title = Entrez Gene: SFRP4 secreted frizzled-related protein 4| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=6424| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Rattner A, Hsieh JC, Smallwood PM, "et al." |title=A family of secreted proteins contains homology to the cysteine-rich ligand-binding domain of frizzled receptors. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=94 |issue= 7 |pages= 2859–63 |year= 1997 |pmid= 9096311 |doi=
*cite journal | author=Wolf V, Ke G, Dharmarajan AM, "et al." |title=DDC-4, an apoptosis-associated gene, is a secreted frizzled relative. |journal=FEBS Lett. |volume=417 |issue= 3 |pages= 385–9 |year= 1998 |pmid= 9409757 |doi=
*cite journal | author=Abu-Jawdeh G, Comella N, Tomita Y, "et al." |title=Differential expression of frpHE: a novel human stromal protein of the secreted frizzled gene family, during the endometrial cycle and malignancy. |journal=Lab. Invest. |volume=79 |issue= 4 |pages= 439–47 |year= 1999 |pmid= 10211996 |doi=
*cite journal | author=Schumann H, Holtz J, Zerkowski HR, Hatzfeld M |title=Expression of secreted frizzled related proteins 3 and 4 in human ventricular myocardium correlates with apoptosis related gene expression. |journal=Cardiovasc. Res. |volume=45 |issue= 3 |pages= 720–8 |year= 2000 |pmid= 10728394 |doi=
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Berndt T, Craig TA, Bowe AE, "et al." |title=Secreted frizzled-related protein 4 is a potent tumor-derived phosphaturic agent. |journal=J. Clin. Invest. |volume=112 |issue= 5 |pages= 785–94 |year= 2003 |pmid= 12952927 |doi= 10.1172/JCI200318563
*cite journal | author=Wissmann C, Wild PJ, Kaiser S, "et al." |title=WIF1, a component of the Wnt pathway, is down-regulated in prostate, breast, lung, and bladder cancer. |journal=J. Pathol. |volume=201 |issue= 2 |pages= 204–12 |year= 2003 |pmid= 14517837 |doi= 10.1002/path.1449
*cite journal | author=Horvath LG, Henshall SM, Kench JG, "et al." |title=Membranous expression of secreted frizzled-related protein 4 predicts for good prognosis in localized prostate cancer and inhibits PC3 cellular proliferation in vitro. |journal=Clin. Cancer Res. |volume=10 |issue= 2 |pages= 615–25 |year= 2004 |pmid= 14760084 |doi=
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Ahn J, Chung KS, Kim DU, "et al." |title=Systematic identification of hepatocellular proteins interacting with NS5A of the hepatitis C virus. |journal=J. Biochem. Mol. Biol. |volume=37 |issue= 6 |pages= 741–8 |year= 2005 |pmid= 15607035 |doi=
*cite journal | author=He B, Lee AY, Dadfarmay S, "et al." |title=Secreted frizzled-related protein 4 is silenced by hypermethylation and induces apoptosis in beta-catenin-deficient human mesothelioma cells. |journal=Cancer Res. |volume=65 |issue= 3 |pages= 743–8 |year= 2005 |pmid= 15705870 |doi=
*cite journal | author=Berndt TJ, Bielesz B, Craig TA, "et al." |title=Secreted frizzled-related protein-4 reduces sodium-phosphate co-transporter abundance and activity in proximal tubule cells. |journal=Pflugers Arch. |volume=451 |issue= 4 |pages= 579–87 |year= 2006 |pmid= 16151791 |doi= 10.1007/s00424-005-1495-2
*cite journal | author=Feng Han Q, Zhao W, Bentel J, "et al." |title=Expression of sFRP-4 and beta-catenin in human colorectal carcinoma. |journal=Cancer Lett. |volume=231 |issue= 1 |pages= 129–37 |year= 2006 |pmid= 16356838 |doi= 10.1016/j.canlet.2005.01.026
*cite journal | author=Urakami S, Shiina H, Enokida H, "et al." |title=Combination analysis of hypermethylated Wnt-antagonist family genes as a novel epigenetic biomarker panel for bladder cancer detection. |journal=Clin. Cancer Res. |volume=12 |issue= 7 Pt 1 |pages= 2109–16 |year= 2006 |pmid= 16609023 |doi= 10.1158/1078-0432.CCR-05-2468
*cite journal | author=Horvath LG, Lelliott JE, Kench JG, "et al." |title=Secreted frizzled-related protein 4 inhibits proliferation and metastatic potential in prostate cancer. |journal=Prostate |volume=67 |issue= 10 |pages= 1081–90 |year= 2007 |pmid= 17476687 |doi= 10.1002/pros.20607

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