CPSF3

CPSF3

Cleavage and polyadenylation specific factor 3, 73kDa, also known as CPSF3, is a human gene.cite web | title = Entrez Gene: CPSF3 cleavage and polyadenylation specific factor 3, 73kDa| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=51692| accessdate = ]

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References

Further reading

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*cite journal | author=Murthy KG, Manley JL |title=The 160-kD subunit of human cleavage-polyadenylation specificity factor coordinates pre-mRNA 3'-end formation. |journal=Genes Dev. |volume=9 |issue= 21 |pages= 2672–83 |year= 1995 |pmid= 7590244 |doi=
*cite journal | author=Jenny A, Hauri HP, Keller W |title=Characterization of cleavage and polyadenylation specificity factor and cloning of its 100-kilodalton subunit. |journal=Mol. Cell. Biol. |volume=14 |issue= 12 |pages= 8183–90 |year= 1994 |pmid= 7969155 |doi=
*cite journal | author=Maruyama K, Sugano S |title=Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides. |journal=Gene |volume=138 |issue= 1-2 |pages= 171–4 |year= 1994 |pmid= 8125298 |doi=
*cite journal | author=Thuresson AC, Aström J, Aström A, "et al." |title=Multiple forms of poly(A) polymerases in human cells. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=91 |issue= 3 |pages= 979–83 |year= 1994 |pmid= 8302877 |doi=
*cite journal | author=Jenny A, Minvielle-Sebastia L, Preker PJ, Keller W |title=Sequence similarity between the 73-kilodalton protein of mammalian CPSF and a subunit of yeast polyadenylation factor I. |journal=Science |volume=274 |issue= 5292 |pages= 1514–7 |year= 1996 |pmid= 8929409 |doi=
*cite journal | author=McCracken S, Fong N, Yankulov K, "et al." |title=The C-terminal domain of RNA polymerase II couples mRNA processing to transcription. |journal=Nature |volume=385 |issue= 6614 |pages= 357–61 |year= 1997 |pmid= 9002523 |doi= 10.1038/385357a0
*cite journal | author=Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, "et al." |title=Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library. |journal=Gene |volume=200 |issue= 1-2 |pages= 149–56 |year= 1997 |pmid= 9373149 |doi=
*cite journal | author=Takagaki Y, Manley JL |title=Complex protein interactions within the human polyadenylation machinery identify a novel component. |journal=Mol. Cell. Biol. |volume=20 |issue= 5 |pages= 1515–25 |year= 2000 |pmid= 10669729 |doi=
*cite journal | author=de Vries H, Rüegsegger U, Hübner W, "et al." |title=Human pre-mRNA cleavage factor II(m) contains homologs of yeast proteins and bridges two other cleavage factors. |journal=EMBO J. |volume=19 |issue= 21 |pages= 5895–904 |year= 2000 |pmid= 11060040 |doi= 10.1093/emboj/19.21.5895
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Kaufmann I, Martin G, Friedlein A, "et al." |title=Human Fip1 is a subunit of CPSF that binds to U-rich RNA elements and stimulates poly(A) polymerase. |journal=EMBO J. |volume=23 |issue= 3 |pages= 616–26 |year= 2005 |pmid= 14749727 |doi= 10.1038/sj.emboj.7600070
*cite journal | author=Calzado MA, Sancho R, Muñoz E |title=Human immunodeficiency virus type 1 Tat increases the expression of cleavage and polyadenylation specificity factor 73-kilodalton subunit modulating cellular and viral expression. |journal=J. Virol. |volume=78 |issue= 13 |pages= 6846–54 |year= 2004 |pmid= 15194760 |doi= 10.1128/JVI.78.13.6846-6854.2004
*cite journal | author=Jin J, Smith FD, Stark C, "et al." |title=Proteomic, functional, and domain-based analysis of in vivo 14-3-3 binding proteins involved in cytoskeletal regulation and cellular organization. |journal=Curr. Biol. |volume=14 |issue= 16 |pages= 1436–50 |year= 2004 |pmid= 15324660 |doi= 10.1016/j.cub.2004.07.051
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Mandel CR, Kaneko S, Zhang H, "et al." |title=Polyadenylation factor CPSF-73 is the pre-mRNA 3'-end-processing endonuclease. |journal=Nature |volume=444 |issue= 7121 |pages= 953–6 |year= 2007 |pmid= 17128255 |doi= 10.1038/nature05363
*cite journal | author=de la Vega L, Sánchez-Duffhues G, Fresno M, "et al." |title=The 73 kDa subunit of the CPSF complex binds to the HIV-1 LTR promoter and functions as a negative regulatory factor that is inhibited by the HIV-1 Tat protein. |journal=J. Mol. Biol. |volume=372 |issue= 2 |pages= 317–30 |year= 2007 |pmid= 17669424 |doi= 10.1016/j.jmb.2007.06.075

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  • Cleavage and polyadenylation specificity factor — (CPSF) (or Cleavage polyadenylation stimulating factor) is involved in the cleavage of the 3 signaling region from a newly synthesized pre messenger RNA (pre mRNA) molecule in the process of gene transcription. It is the first protein to bind to… …   Wikipedia

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