VPS28

VPS28

Vacuolar protein sorting 28 homolog (S. cerevisiae), also known as VPS28, is a human gene.cite web | title = Entrez Gene: VPS28 vacuolar protein sorting 28 homolog (S. cerevisiae)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=51160| accessdate = ]

PBB_Summary
section_title =
summary_text = This gene encodes a protein involved in endosomal sorting of cell surface receptors via a multivesicular body/late endosome pathway. The encoded protein is one of the three subunits of the ESCRT-I complex (endosomal complexes required for transport) involved in the sorting of ubiquitinated proteins. The two other subunits of ESCRT-I are vesicular protein sorting 23, also known as tumor susceptibility gene 101 (TSG101), and vesicular protein sorting 37. Two alternative transcripts encoding different isoforms have been described. Additional alternative transcripts may exist but the proteins encoded by these transcripts have not been verified experimentally.cite web | title = Entrez Gene: VPS28 vacuolar protein sorting 28 homolog (S. cerevisiae)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=51160| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Raiborg C, Rusten TE, Stenmark H |title=Protein sorting into multivesicular endosomes. |journal=Curr. Opin. Cell Biol. |volume=15 |issue= 4 |pages= 446–55 |year= 2004 |pmid= 12892785 |doi=
*cite journal | author=Bishop N, Woodman P |title=TSG101/mammalian VPS23 and mammalian VPS28 interact directly and are recruited to VPS4-induced endosomes. |journal=J. Biol. Chem. |volume=276 |issue= 15 |pages= 11735–42 |year= 2001 |pmid= 11134028 |doi= 10.1074/jbc.M009863200
*cite journal | author=Suzuki H, Fukunishi Y, Kagawa I, "et al." |title=Protein-protein interaction panel using mouse full-length cDNAs. |journal=Genome Res. |volume=11 |issue= 10 |pages= 1758–65 |year= 2001 |pmid= 11591653 |doi= 10.1101/gr.180101
*cite journal | author=Bishop N, Horman A, Woodman P |title=Mammalian class E vps proteins recognize ubiquitin and act in the removal of endosomal protein-ubiquitin conjugates. |journal=J. Cell Biol. |volume=157 |issue= 1 |pages= 91–101 |year= 2002 |pmid= 11916981 |doi= 10.1083/jcb.200112080
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Martin-Serrano J, Zang T, Bieniasz PD |title=Role of ESCRT-I in retroviral budding. |journal=J. Virol. |volume=77 |issue= 8 |pages= 4794–804 |year= 2003 |pmid= 12663786 |doi=
*cite journal | author=Tanzi GO, Piefer AJ, Bates P |title=Equine infectious anemia virus utilizes host vesicular protein sorting machinery during particle release. |journal=J. Virol. |volume=77 |issue= 15 |pages= 8440–7 |year= 2003 |pmid= 12857913 |doi=
*cite journal | author=Martin-Serrano J, Yarovoy A, Perez-Caballero D, "et al." |title=Divergent retroviral late-budding domains recruit vacuolar protein sorting factors by using alternative adaptor proteins. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=100 |issue= 21 |pages= 12414–9 |year= 2003 |pmid= 14519844 |doi= 10.1073/pnas.2133846100
*cite journal | author=Ota T, Suzuki Y, Nishikawa T, "et al." |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285
*cite journal | author=Stuchell MD, Garrus JE, Müller B, "et al." |title=The human endosomal sorting complex required for transport (ESCRT-I) and its role in HIV-1 budding. |journal=J. Biol. Chem. |volume=279 |issue= 34 |pages= 36059–71 |year= 2005 |pmid= 15218037 |doi= 10.1074/jbc.M405226200
*cite journal | author=Bache KG, Slagsvold T, Cabezas A, "et al." |title=The growth-regulatory protein HCRP1/hVps37A is a subunit of mammalian ESCRT-I and mediates receptor down-regulation. |journal=Mol. Biol. Cell |volume=15 |issue= 9 |pages= 4337–46 |year= 2005 |pmid= 15240819 |doi= 10.1091/mbc.E04-03-0250
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Eastman SW, Martin-Serrano J, Chung W, "et al." |title=Identification of human VPS37C, a component of endosomal sorting complex required for transport-I important for viral budding. |journal=J. Biol. Chem. |volume=280 |issue= 1 |pages= 628–36 |year= 2005 |pmid= 15509564 |doi= 10.1074/jbc.M410384200
*cite journal | author=Rual JF, Venkatesan K, Hao T, "et al." |title=Towards a proteome-scale map of the human protein-protein interaction network. |journal=Nature |volume=437 |issue= 7062 |pages= 1173–8 |year= 2005 |pmid= 16189514 |doi= 10.1038/nature04209
*cite journal | author=Hui EK, Barman S, Tang DH, "et al." |title=YRKL sequence of influenza virus M1 functions as the L domain motif and interacts with VPS28 and Cdc42. |journal=J. Virol. |volume=80 |issue= 5 |pages= 2291–308 |year= 2006 |pmid= 16474136 |doi= 10.1128/JVI.80.5.2291-2308.2006

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  • TSG101 — Tumor susceptibility gene 101, also known as TSG101, is a human gene that encodes for a cellular protein of the same name. PBB Summary section title = summary text = The protein encoded by this gene belongs to a group of apparently inactive… …   Wikipedia

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