KLK14

Kallikrein-related peptidase 14, also known as KLK14, is a human gene.cite web | title = Entrez Gene: KLK14 kallikrein-related peptidase 14| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=43847| accessdate = ]

PBB_Summary
section_title =
summary_text = Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. An additional transcript variant has been described but its full length nature has not been determined.cite web | title = Entrez Gene: KLK14 kallikrein-related peptidase 14| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=43847| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Harvey TJ, Hooper JD, Myers SA, "et al." |title=Tissue-specific expression patterns and fine mapping of the human kallikrein (KLK) locus on proximal 19q13.4. |journal=J. Biol. Chem. |volume=275 |issue= 48 |pages= 37397–406 |year= 2001 |pmid= 10969073 |doi= 10.1074/jbc.M004525200
*cite journal | author=Yousef GM, Magklara A, Chang A, "et al." |title=Cloning of a new member of the human kallikrein gene family, KLK14, which is down-regulated in different malignancies. |journal=Cancer Res. |volume=61 |issue= 8 |pages= 3425–31 |year= 2001 |pmid= 11309303 |doi=
*cite journal | author=Hooper JD, Bui LT, Rae FK, "et al." |title=Identification and characterization of KLK14, a novel kallikrein serine protease gene located on human chromosome 19q13.4 and expressed in prostate and skeletal muscle. |journal=Genomics |volume=73 |issue= 1 |pages= 117–22 |year= 2001 |pmid= 11352573 |doi= 10.1006/geno.2000.6490
*cite journal | author=Yousef GM, Borgoño CA, Scorilas A, "et al." |title=Quantitative analysis of human kallikrein gene 14 expression in breast tumours indicates association with poor prognosis. |journal=Br. J. Cancer |volume=87 |issue= 11 |pages= 1287–93 |year= 2003 |pmid= 12439719 |doi= 10.1038/sj.bjc.6600623
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Yousef GM, Stephan C, Scorilas A, "et al." |title=Differential expression of the human kallikrein gene 14 (KLK14) in normal and cancerous prostatic tissues. |journal=Prostate |volume=56 |issue= 4 |pages= 287–92 |year= 2003 |pmid= 12858357 |doi= 10.1002/pros.10263
*cite journal | author=Grimwood J, Gordon LA, Olsen A, "et al." |title=The DNA sequence and biology of human chromosome 19. |journal=Nature |volume=428 |issue= 6982 |pages= 529–35 |year= 2004 |pmid= 15057824 |doi= 10.1038/nature02399
*cite journal | author=Brattsand M, Stefansson K, Lundh C, "et al." |title=A proteolytic cascade of kallikreins in the stratum corneum. |journal=J. Invest. Dermatol. |volume=124 |issue= 1 |pages= 198–203 |year= 2005 |pmid= 15654974 |doi= 10.1111/j.0022-202X.2004.23547.x
*cite journal | author=Felber LM, Borgoño CA, Cloutier SM, "et al." |title=Enzymatic profiling of human kallikrein 14 using phage-display substrate technology. |journal=Biol. Chem. |volume=386 |issue= 3 |pages= 291–8 |year= 2005 |pmid= 15843175 |doi= 10.1515/BC.2005.035
*cite journal | author=Fritzsche F, Gansukh T, Borgoño CA, "et al." |title=Expression of human Kallikrein 14 (KLK14) in breast cancer is associated with higher tumour grades and positive nodal status. |journal=Br. J. Cancer |volume=94 |issue= 4 |pages= 540–7 |year= 2006 |pmid= 16434994 |doi= 10.1038/sj.bjc.6602956
*cite journal | author= |title=Proceedings of the 1st International Symposium on Kallikreins, Lausanne, Switzerland, September 1-3 , 2005. |journal=Biol. Chem. |volume=387 |issue= 6 |pages= 635–824 |year= 2006 |pmid= 16800723 |doi= 10.1515/BC.2006.081
*cite journal | author=Lundwall A, Band V, Blaber M, "et al." |title=A comprehensive nomenclature for serine proteases with homology to tissue kallikreins. |journal=Biol. Chem. |volume=387 |issue= 6 |pages= 637–41 |year= 2006 |pmid= 16800724 |doi= 10.1515/BC.2006.082
*cite journal | author=Stefansson K, Brattsand M, Ny A, "et al." |title=Kallikrein-related peptidase 14 may be a major contributor to trypsin-like proteolytic activity in human stratum corneum. |journal=Biol. Chem. |volume=387 |issue= 6 |pages= 761–8 |year= 2006 |pmid= 16800737 |doi= 10.1515/BC.2006.095
*cite journal | author=Borgoño CA, Michael IP, Shaw JL, "et al." |title=Expression and functional characterization of the cancer-related serine protease, human tissue kallikrein 14. |journal=J. Biol. Chem. |volume=282 |issue= 4 |pages= 2405–22 |year= 2007 |pmid= 17110383 |doi= 10.1074/jbc.M608348200
*cite journal | author=Borgoño CA, Michael IP, Komatsu N, "et al." |title=A potential role for multiple tissue kallikrein serine proteases in epidermal desquamation. |journal=J. Biol. Chem. |volume=282 |issue= 6 |pages= 3640–52 |year= 2007 |pmid= 17158887 |doi= 10.1074/jbc.M607567200

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