- CLDN11
Claudin 11 (oligodendrocyte transmembrane protein), also known as CLDN11, is a human
gene .cite web | title = Entrez Gene: CLDN11 claudin 11 (oligodendrocyte transmembrane protein)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=5010| accessdate = ] It belongs to the group ofclaudin s.PBB_Summary
section_title =
summary_text = The protein encoded by this gene belongs to the claudin family of tight junction associated proteins and is a major component of central nervous system myelin that is necessary for normal CNS function. There is growing evidence that the protein determines the permeability between layers of myelin sheaths via focal adhesion and, with its expression highly regulated during development, may play an important role in cellular proliferation and migration. In addition, the protein is a candidate autoantigen in the development of autoimmune demyelinating disease.cite web | title = Entrez Gene: CLDN11 claudin 11 (oligodendrocyte transmembrane protein)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=5010| accessdate = ]References
Further reading
PBB_Further_reading
citations =
*cite journal | author=Kniesel U, Wolburg H |title=Tight junctions of the blood-brain barrier. |journal=Cell. Mol. Neurobiol. |volume=20 |issue= 1 |pages= 57–76 |year= 2000 |pmid= 10690502 |doi=
*cite journal | author=Bronstein JM, Tiwari-Woodruff S, Buznikov AG, Stevens DB |title=Involvement of OSP/claudin-11 in oligodendrocyte membrane interactions: role in biology and disease. |journal=J. Neurosci. Res. |volume=59 |issue= 6 |pages= 706–11 |year= 2000 |pmid= 10700007 |doi=
*cite journal | author=Heiskala M, Peterson PA, Yang Y |title=The roles of claudin superfamily proteins in paracellular transport. |journal=Traffic |volume=2 |issue= 2 |pages= 93–8 |year= 2001 |pmid= 11247307 |doi=
*cite journal | author=Tsukita S, Furuse M, Itoh M |title=Multifunctional strands in tight junctions. |journal=Nat. Rev. Mol. Cell Biol. |volume=2 |issue= 4 |pages= 285–93 |year= 2001 |pmid= 11283726 |doi= 10.1038/35067088
*cite journal | author=Tsukita S, Furuse M |title=Claudin-based barrier in simple and stratified cellular sheets. |journal=Curr. Opin. Cell Biol. |volume=14 |issue= 5 |pages= 531–6 |year= 2003 |pmid= 12231346 |doi=
*cite journal | author=González-Mariscal L, Betanzos A, Nava P, Jaramillo BE |title=Tight junction proteins. |journal=Prog. Biophys. Mol. Biol. |volume=81 |issue= 1 |pages= 1–44 |year= 2003 |pmid= 12475568 |doi=
*cite journal | author=Bronstein JM, Kozak CA, Chen XN, "et al." |title=Chromosomal localization of murine and human oligodendrocyte-specific protein genes. |journal=Genomics |volume=34 |issue= 2 |pages= 255–7 |year= 1997 |pmid= 8661061 |doi= 10.1006/geno.1996.0278
*cite journal | author=Bronstein JM, Popper P, Micevych PE, Farber DB |title=Isolation and characterization of a novel oligodendrocyte-specific protein. |journal=Neurology |volume=47 |issue= 3 |pages= 772–8 |year= 1996 |pmid= 8797478 |doi=
*cite journal | author=Shafit-Zagardo B, Kress Y, Zhao ML, Lee SC |title=A novel microtubule-associated protein-2 expressed in oligodendrocytes in multiple sclerosis lesions. |journal=J. Neurochem. |volume=73 |issue= 6 |pages= 2531–7 |year= 1999 |pmid= 10582615 |doi=
*cite journal | author=Gow A, Southwood CM, Li JS, "et al." |title=CNS myelin and sertoli cell tight junction strands are absent in Osp/claudin-11 null mice. |journal=Cell |volume=99 |issue= 6 |pages= 649–59 |year= 2000 |pmid= 10612400 |doi=
*cite journal | author=Bronstein JM, Chen K, Tiwari-Woodruff S, Kornblum HI |title=Developmental expression of OSP/claudin-11. |journal=J. Neurosci. Res. |volume=60 |issue= 3 |pages= 284–90 |year= 2000 |pmid= 10797530 |doi=
*cite journal | author=Tiwari-Woodruff SK, Buznikov AG, Vu TQ, "et al." |title=OSP/claudin-11 forms a complex with a novel member of the tetraspanin super family and beta1 integrin and regulates proliferation and migration of oligodendrocytes. |journal=J. Cell Biol. |volume=153 |issue= 2 |pages= 295–305 |year= 2001 |pmid= 11309411 |doi=
*cite journal | author=Suzuki H, Fukunishi Y, Kagawa I, "et al." |title=Protein-protein interaction panel using mouse full-length cDNAs. |journal=Genome Res. |volume=11 |issue= 10 |pages= 1758–65 |year= 2001 |pmid= 11591653 |doi= 10.1101/gr.180101
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899PBB_Controls
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