- QKI
Quaking homolog, KH domain RNA binding (mouse), also known as QKI, is a human
gene .cite web | title = Entrez Gene: QKI quaking homolog, KH domain RNA binding (mouse)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=9444| accessdate = ]PBB_Summary
section_title =
summary_text = QKI belongs to a family of RNA-binding proteins that have an HNRNPK (MIM 600712) homology (KH) domain embedded in a 200-amino acid region called the GSG domain. Other members of this family include SAM68 (KHDRBS1; MIM 602489) and SF1 (MIM 601516) (Chen and Richard, 1998). [supplied by OMIM] cite web | title = Entrez Gene: QKI quaking homolog, KH domain RNA binding (mouse)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=9444| accessdate = ]References
Further reading
PBB_Further_reading
citations =
*cite journal | author=Robertson NG, Khetarpal U, Gutiérrez-Espeleta GA, "et al." |title=Isolation of novel and known genes from a human fetal cochlear cDNA library using subtractive hybridization and differential screening. |journal=Genomics |volume=23 |issue= 1 |pages= 42–50 |year= 1995 |pmid= 7829101 |doi= 10.1006/geno.1994.1457
*cite journal | author=Saccomanno L, Loushin C, Jan E, "et al." |title=The STAR protein QKI-6 is a translational repressor. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=96 |issue= 22 |pages= 12605–10 |year= 1999 |pmid= 10535969 |doi=
*cite journal | author=Li ZZ, Kondo T, Murata T, "et al." |title=Expression of Hqk encoding a KH RNA binding protein is altered in human glioma. |journal=Jpn. J. Cancer Res. |volume=93 |issue= 2 |pages= 167–77 |year= 2002 |pmid= 11856480 |doi=
*cite journal | author=Wu JI, Reed RB, Grabowski PJ, Artzt K |title=Function of quaking in myelination: regulation of alternative splicing. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 7 |pages= 4233–8 |year= 2002 |pmid= 11917126 |doi= 10.1073/pnas.072090399
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Moore FL, Jaruzelska J, Fox MS, "et al." |title=Human Pumilio-2 is expressed in embryonic stem cells and germ cells and interacts with DAZ (Deleted in AZoospermia) and DAZ-like proteins. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=100 |issue= 2 |pages= 538–43 |year= 2003 |pmid= 12511597 |doi= 10.1073/pnas.0234478100
*cite journal | author=Côté J, Boisvert FM, Boulanger MC, "et al." |title=Sam68 RNA binding protein is an in vivo substrate for protein arginine N-methyltransferase 1. |journal=Mol. Biol. Cell |volume=14 |issue= 1 |pages= 274–87 |year= 2003 |pmid= 12529443 |doi= 10.1091/mbc.E02-08-0484
*cite journal | author=Mungall AJ, Palmer SA, Sims SK, "et al." |title=The DNA sequence and analysis of human chromosome 6. |journal=Nature |volume=425 |issue= 6960 |pages= 805–11 |year= 2003 |pmid= 14574404 |doi= 10.1038/nature02055
*cite journal | author=Ota T, Suzuki Y, Nishikawa T, "et al." |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Rual JF, Venkatesan K, Hao T, "et al." |title=Towards a proteome-scale map of the human protein-protein interaction network. |journal=Nature |volume=437 |issue= 7062 |pages= 1173–8 |year= 2005 |pmid= 16189514 |doi= 10.1038/nature04209
*cite journal | author=Ichimura K, Mungall AJ, Fiegler H, "et al." |title=Small regions of overlapping deletions on 6q26 in human astrocytic tumours identified using chromosome 6 tile path array-CGH. |journal=Oncogene |volume=25 |issue= 8 |pages= 1261–71 |year= 2006 |pmid= 16205629 |doi= 10.1038/sj.onc.1209156
*cite journal | author=Aberg K, Saetre P, Lindholm E, "et al." |title=Human QKI, a new candidate gene for schizophrenia involved in myelination. |journal=Am. J. Med. Genet. B Neuropsychiatr. Genet. |volume=141 |issue= 1 |pages= 84–90 |year= 2006 |pmid= 16342280 |doi= 10.1002/ajmg.b.30243
*cite journal | author=Aberg K, Saetre P, Jareborg N, Jazin E |title=Human QKI, a potential regulator of mRNA expression of human oligodendrocyte-related genes involved in schizophrenia. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=103 |issue= 19 |pages= 7482–7 |year= 2006 |pmid= 16641098 |doi= 10.1073/pnas.0601213103
*cite journal | author=Lim J, Hao T, Shaw C, "et al." |title=A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration. |journal=Cell |volume=125 |issue= 4 |pages= 801–14 |year= 2006 |pmid= 16713569 |doi= 10.1016/j.cell.2006.03.032
*cite journal | author=Haroutunian V, Katsel P, Dracheva S, Davis KL |title=The human homolog of the QKI gene affected in the severe dysmyelination "quaking" mouse phenotype: downregulated in multiple brain regions in schizophrenia. |journal=The American journal of psychiatry |volume=163 |issue= 10 |pages= 1834–7 |year= 2006 |pmid= 17012699 |doi= 10.1176/appi.ajp.163.10.1834
*cite journal | author=Zhao L, Tian D, Xia M, "et al." |title=Rescuing qkV dysmyelination by a single isoform of the selective RNA-binding protein QKI. |journal=J. Neurosci. |volume=26 |issue= 44 |pages= 11278–86 |year= 2006 |pmid= 17079655 |doi= 10.1523/JNEUROSCI.2677-06.2006PBB_Controls
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