GGH (gene)

Gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase), also known as GGH, is a human gene.cite web | title = Entrez Gene: GGH gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=8836| accessdate = ]

PBB_Summary
section_title =
summary_text = This gene catalyzes the hydrolysis of folylpoly-gamma-glutamates and antifolylpoly-gamma-glutamates by the removal of gamma-linked polyglutamates and glutamate.cite web | title = Entrez Gene: GGH gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=8836| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Galivan J, Ryan T, Rhee M, "et al." |title=Glutamyl hydrolase: properties and pharmacologic impact. |journal=Semin. Oncol. |volume=26 |issue= 2 Suppl 6 |pages= 33–7 |year= 1999 |pmid= 10598552 |doi=
*cite journal | author=O'Connor BM, Rotundo RF, Nimec Z, "et al." |title=Secretion of gamma-glutamyl hydrolase in vitro. |journal=Cancer Res. |volume=51 |issue= 15 |pages= 3874–81 |year= 1991 |pmid= 1713122 |doi=
*cite journal | author=Chandler CJ, Wang TT, Halsted CH |title=Pteroylpolyglutamate hydrolase from human jejunal brush borders. Purification and characterization. |journal=J. Biol. Chem. |volume=261 |issue= 2 |pages= 928–33 |year= 1986 |pmid= 2867095 |doi=
*cite journal | author=Wang TT, Chandler CJ, Halsted CH |title=Intracellular pteroylpolyglutamate hydrolase from human jejunal mucosa. Isolation and characterization. |journal=J. Biol. Chem. |volume=261 |issue= 29 |pages= 13551–5 |year= 1986 |pmid= 3759978 |doi=
*cite journal | author=Yao R, Nimec Z, Ryan TJ, Galivan J |title=Identification, cloning, and sequencing of a cDNA coding for rat gamma-glutamyl hydrolase. |journal=J. Biol. Chem. |volume=271 |issue= 15 |pages= 8525–8 |year= 1996 |pmid= 8621474 |doi=
*cite journal | author=Yao R, Schneider E, Ryan TJ, Galivan J |title=Human gamma-glutamyl hydrolase: cloning and characterization of the enzyme expressed in vitro. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=93 |issue= 19 |pages= 10134–8 |year= 1996 |pmid= 8816764 |doi=
*cite journal | author=Rhee MS, Lindau-Shepard B, Chave KJ, "et al." |title=Characterization of human cellular gamma-glutamyl hydrolase. |journal=Mol. Pharmacol. |volume=53 |issue= 6 |pages= 1040–6 |year= 1998 |pmid= 9614206 |doi=
*cite journal | author=Yin D, Chave KJ, Macaluso CR, "et al." |title=Structural organization of the human gamma-glutamyl hydrolase gene. |journal=Gene |volume=238 |issue= 2 |pages= 463–70 |year= 1999 |pmid= 10570974 |doi=
*cite journal | author=Li H, Ryan TJ, Chave KJ, Van Roey P |title=Three-dimensional structure of human gamma -glutamyl hydrolase. A class I glatamine amidotransferase adapted for a complex substate. |journal=J. Biol. Chem. |volume=277 |issue= 27 |pages= 24522–9 |year= 2002 |pmid= 11953431 |doi= 10.1074/jbc.M202020200
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Basrur V, Yang F, Kushimoto T, "et al." |title=Proteomic analysis of early melanosomes: identification of novel melanosomal proteins. |journal=J. Proteome Res. |volume=2 |issue= 1 |pages= 69–79 |year= 2003 |pmid= 12643545 |doi=
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=He P, Varticovski L, Bowman ED, "et al." |title=Identification of carboxypeptidase E and gamma-glutamyl hydrolase as biomarkers for pulmonary neuroendocrine tumors by cDNA microarray. |journal=Hum. Pathol. |volume=35 |issue= 10 |pages= 1196–209 |year= 2004 |pmid= 15492986 |doi=
*cite journal | author=Rual JF, Venkatesan K, Hao T, "et al." |title=Towards a proteome-scale map of the human protein-protein interaction network. |journal=Nature |volume=437 |issue= 7062 |pages= 1173–8 |year= 2005 |pmid= 16189514 |doi= 10.1038/nature04209
*cite journal | author=Eisele LE, Chave KJ, Lehning AC, Ryan TJ |title=Characterization of Human gamma-glutamyl hydrolase in solution demonstrates that the enzyme is a non-dissociating homodimer. |journal=Biochim. Biophys. Acta |volume=1764 |issue= 9 |pages= 1479–86 |year= 2006 |pmid= 16945597 |doi= 10.1016/j.bbapap.2006.06.008
*cite journal | author=Chi A, Valencia JC, Hu ZZ, "et al." |title=Proteomic and bioinformatic characterization of the biogenesis and function of melanosomes. |journal=J. Proteome Res. |volume=5 |issue= 11 |pages= 3135–44 |year= 2007 |pmid= 17081065 |doi= 10.1021/pr060363j
*cite journal | author=Hayashi H, Fujimaki C, Inoue K, "et al." |title=Genetic polymorphism of C452T (T127I) in human gamma-glutamyl hydrolase in a Japanese population. |journal=Biol. Pharm. Bull. |volume=30 |issue= 4 |pages= 839–41 |year= 2007 |pmid= 17409534 |doi=

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