- SULT1C2
Sulfotransferase family, cytosolic, 1C, member 1, also known as SULT1C1, is a human
gene .cite web | title = Entrez Gene: SULT1C1 sulfotransferase family, cytosolic, 1C, member 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=6819| accessdate = ]PBB_Summary
section_title =
summary_text = Sulfotransferase enzymes catalyze the sulfate conjugation of many hormones, neurotransmitters, drugs, and xenobiotic compounds. These cytosolic enzymes are different in their tissue distributions and substrate specificities. The gene structure (number and length of exons) is similar among family members. This gene encodes a protein that belongs to the SULT1 subfamily, responsible for transferring a sulfo moiety from PAPS to phenol-containing compounds. Two alternatively spliced transcript variants encoding different isoforms have been described for this gene.cite web | title = Entrez Gene: SULT1C1 sulfotransferase family, cytosolic, 1C, member 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=6819| accessdate = ]References
Further reading
PBB_Further_reading
citations =
*cite journal | author=Weinshilboum RM, Otterness DM, Aksoy IA, "et al." |title=Sulfation and sulfotransferases 1: Sulfotransferase molecular biology: cDNAs and genes. |journal=FASEB J. |volume=11 |issue= 1 |pages= 3–14 |year= 1997 |pmid= 9034160 |doi=
*cite journal | author=Glatt H, Engelke CE, Pabel U, "et al." |title=Sulfotransferases: genetics and role in toxicology. |journal=Toxicol. Lett. |volume=112-113 |issue= |pages= 341–8 |year= 2000 |pmid= 10720750 |doi=
*cite journal | author=Glatt H |title=Sulfotransferases in the bioactivation of xenobiotics. |journal=Chem. Biol. Interact. |volume=129 |issue= 1-2 |pages= 141–70 |year= 2001 |pmid= 11154739 |doi=
*cite journal | author=Glatt H, Boeing H, Engelke CE, "et al." |title=Human cytosolic sulphotransferases: genetics, characteristics, toxicological aspects. |journal=Mutat. Res. |volume=482 |issue= 1-2 |pages= 27–40 |year= 2001 |pmid= 11535246 |doi=
*cite journal | author=Kiehlbauch CC, Lam YF, Ringer DP |title=Homodimeric and heterodimeric aryl sulfotransferases catalyze the sulfuric acid esterification of N-hydroxy-2-acetylaminofluorene. |journal=J. Biol. Chem. |volume=270 |issue= 32 |pages= 18941–7 |year= 1995 |pmid= 7642552 |doi=
*cite journal | author=Her C, Kaur GP, Athwal RS, Weinshilboum RM |title=Human sulfotransferase SULT1C1: cDNA cloning, tissue-specific expression, and chromosomal localization. |journal=Genomics |volume=41 |issue= 3 |pages= 467–70 |year= 1997 |pmid= 9169148 |doi=
*cite journal | author=Yoshinari K, Nagata K, Shimada M, Yamazoe Y |title=Molecular characterization of ST1C1-related human sulfotransferase. |journal=Carcinogenesis |volume=19 |issue= 5 |pages= 951–3 |year= 1998 |pmid= 9635888 |doi=
*cite journal | author=Sakakibara Y, Yanagisawa K, Katafuchi J, "et al." |title=Molecular cloning, expression, and characterization of novel human SULT1C sulfotransferases that catalyze the sulfonation of N-hydroxy-2-acetylaminofluorene. |journal=J. Biol. Chem. |volume=273 |issue= 51 |pages= 33929–35 |year= 1999 |pmid= 9852044 |doi=
*cite journal | author=Hehonah N, Zhu X, Brix L, "et al." |title=Molecular cloning, expression, localisation and functional characterisation of a rabbit SULT1C2 sulfotransferase. |journal=Int. J. Biochem. Cell Biol. |volume=31 |issue= 8 |pages= 869–82 |year= 1999 |pmid= 10481272 |doi=
*cite journal | author=Freimuth RR, Raftogianis RB, Wood TC, "et al." |title=Human sulfotransferases SULT1C1 and SULT1C2: cDNA characterization, gene cloning, and chromosomal localization. |journal=Genomics |volume=65 |issue= 2 |pages= 157–65 |year= 2000 |pmid= 10783263 |doi= 10.1006/geno.2000.6150
*cite journal | author=Li X, Clemens DL, Anderson RJ |title=Sulfation of iodothyronines by human sulfotransferase 1C1 (SULT1C1)*. |journal=Biochem. Pharmacol. |volume=60 |issue= 11 |pages= 1713–6 |year= 2000 |pmid= 11077054 |doi=
*cite journal | author=Freimuth RR, Eckloff B, Wieben ED, Weinshilboum RM |title=Human sulfotransferase SULT1C1 pharmacogenetics: gene resequencing and functional genomic studies. |journal=Pharmacogenetics |volume=11 |issue= 9 |pages= 747–56 |year= 2002 |pmid= 11740338 |doi=
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Rual JF, Venkatesan K, Hao T, "et al." |title=Towards a proteome-scale map of the human protein-protein interaction network. |journal=Nature |volume=437 |issue= 7062 |pages= 1173–8 |year= 2005 |pmid= 16189514 |doi= 10.1038/nature04209
*cite journal | author=Dombrovski L, Dong A, Bochkarev A, Plotnikov AN |title=Crystal structures of human sulfotransferases SULT1B1 and SULT1C1 complexed with the cofactor product adenosine-3'- 5'-diphosphate (PAP). |journal=Proteins |volume=64 |issue= 4 |pages= 1091–4 |year= 2006 |pmid= 16804942 |doi= 10.1002/prot.21048PBB_Controls
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