[cite web | title = Entrez Gene: SIX3 sine oculis homeobox homolog 3 (Drosophila)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=6496| accessdate = ] ] PBB_Summary
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References
Further reading
PBB_Further_reading
citations =
*cite journal | author=Hecht BK, Hecht F, Münke M |title=Forebrain cleavage gene causing holoprosencephaly: deletion mapping to chromosome band 2p21. |journal=Am. J. Med. Genet. |volume=40 |issue= 1 |pages= 130 |year= 1991 |pmid= 1887845 |doi= 10.1002/ajmg.1320400131
*cite journal | author=Granadino B, Gallardo ME, López-Ríos J, "et al." |title=Genomic cloning, structure, expression pattern, and chromosomal location of the human SIX3 gene. |journal=Genomics |volume=55 |issue= 1 |pages= 100–5 |year= 1999 |pmid= 9889003 |doi=
*cite journal | author=Wallis DE, Roessler E, Hehr U, "et al." |title=Mutations in the homeodomain of the human SIX3 gene cause holoprosencephaly. |journal=Nat. Genet. |volume=22 |issue= 2 |pages= 196–8 |year= 1999 |pmid= 10369266 |doi= 10.1038/9718
*cite journal | author=Leppert GS, Yang JM, Sundin OH |title=Sequence and location of SIX3, a homeobox gene expressed in the human eye. |journal=Ophthalmic Genet. |volume=20 |issue= 1 |pages= 7–21 |year= 1999 |pmid= 10415461 |doi=
*cite journal | author=Ohto H, Kamada S, Tago K, "et al." |title=Cooperation of six and eya in activation of their target genes through nuclear translocation of Eya. |journal=Mol. Cell. Biol. |volume=19 |issue= 10 |pages= 6815–24 |year= 2000 |pmid= 10490620 |doi=
*cite journal | author=Mikkola I, Bruun JA, Holm T, Johansen T |title=Superactivation of Pax6-mediated transactivation from paired domain-binding sites by dna-independent recruitment of different homeodomain proteins. |journal=J. Biol. Chem. |volume=276 |issue= 6 |pages= 4109–18 |year= 2001 |pmid= 11069920 |doi= 10.1074/jbc.M008882200
*cite journal | author=Ohkura N, Ohkubo T, Maruyama K, "et al." |title=The orphan nuclear receptor NOR-1 interacts with the homeobox containing protein Six3. |journal=Dev. Neurosci. |volume=23 |issue= 1 |pages= 17–24 |year= 2001 |pmid= 11173923 |doi=
*cite journal | author=Lengler J, Graw J |title=Regulation of the human SIX3 gene promoter. |journal=Biochem. Biophys. Res. Commun. |volume=287 |issue= 2 |pages= 372–6 |year= 2001 |pmid= 11554737 |doi= 10.1006/bbrc.2001.5605
*cite journal | author=Zhu CC, Dyer MA, Uchikawa M, "et al." |title=Six3-mediated auto repression and eye development requires its interaction with members of the Groucho-related family of co-repressors. |journal=Development |volume=129 |issue= 12 |pages= 2835–49 |year= 2002 |pmid= 12050133 |doi=
*cite journal | author=López-Ríos J, Tessmar K, Loosli F, "et al." |title=Six3 and Six6 activity is modulated by members of the groucho family. |journal=Development |volume=130 |issue= 1 |pages= 185–95 |year= 2003 |pmid= 12441302 |doi=
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Laflamme C, Filion C, Bridge JA, "et al." |title=The homeotic protein Six3 is a coactivator of the nuclear receptor NOR-1 and a corepressor of the fusion protein EWS/NOR-1 in human extraskeletal myxoid chondrosarcomas. |journal=Cancer Res. |volume=63 |issue= 2 |pages= 449–54 |year= 2003 |pmid= 12543801 |doi=
*cite journal | author=Del Bene F, Tessmar-Raible K, Wittbrodt J |title=Direct interaction of geminin and Six3 in eye development. |journal=Nature |volume=427 |issue= 6976 |pages= 745–9 |year= 2004 |pmid= 14973488 |doi= 10.1038/nature02292
*cite journal | author=Dubourg C, Lazaro L, Pasquier L, "et al." |title=Molecular screening of SHH, ZIC2, SIX3, and TGIF genes in patients with features of holoprosencephaly spectrum: Mutation review and genotype-phenotype correlations. |journal=Hum. Mutat. |volume=24 |issue= 1 |pages= 43–51 |year= 2004 |pmid= 15221788 |doi= 10.1002/humu.20056
*cite journal | author=Laflamme C, Filion C, Labelle Y |title=Functional characterization of SIX3 homeodomain mutations in holoprosencephaly: interaction with the nuclear receptor NR4A3/NOR1. |journal=Hum. Mutat. |volume=24 |issue= 6 |pages= 502–8 |year= 2005 |pmid= 15523651 |doi= 10.1002/humu.20102
*cite journal | author=Pasquier L, Dubourg C, Gonzales M, "et al." |title=First occurrence of aprosencephaly/atelencephaly and holoprosencephaly in a family with a SIX3 gene mutation and phenotype/genotype correlation in our series of SIX3 mutations. |journal=J. Med. Genet. |volume=42 |issue= 1 |pages= e4 |year= 2006 |pmid= 15635066 |doi= 10.1136/jmg.2004.023416
*cite journal | author=Bendavid C, Dubourg C, Gicquel I, "et al." |title=Molecular evaluation of foetuses with holoprosencephaly shows high incidence of microdeletions in the HPE genes. |journal=Hum. Genet. |volume=119 |issue= 1-2 |pages= 1–8 |year= 2007 |pmid= 16323008 |doi= 10.1007/s00439-005-0097-6
*cite journal | author=Manavathi B, Peng S, Rayala SK, "et al." |title=Repression of Six3 by a corepressor regulates rhodopsin expression. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=104 |issue= 32 |pages= 13128–33 |year= 2007 |pmid= 17666527 |doi= 10.1073/pnas.0705878104
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