RPS14

Ribosomal protein S14, also known as RPS14, is a human gene.cite web | title = Entrez Gene: RPS14 ribosomal protein S14| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=6208| accessdate = ]

PBB_Summary
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summary_text = Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 40S subunit. The protein belongs to the S11P family of ribosomal proteins. It is located in the cytoplasm. Transcript variants utilizing alternative transcription initiation sites have been described in the literature. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. In Chinese hamster ovary cells, mutations in this gene can lead to resistance to emetine, a protein synthesis inhibitor. Multiple alternatively spliced transcript variants encoding the same protein have been found for this gene.cite web | title = Entrez Gene: RPS14 ribosomal protein S14| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=6208| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Wool IG, Chan YL, Glück A |title=Structure and evolution of mammalian ribosomal proteins. |journal=Biochem. Cell Biol. |volume=73 |issue= 11-12 |pages= 933–47 |year= 1996 |pmid= 8722009 |doi=
*cite journal | author=Diaz JJ, Roufa DJ |title=Fine-structure map of the human ribosomal protein gene RPS14. |journal=Mol. Cell. Biol. |volume=12 |issue= 4 |pages= 1680–6 |year= 1992 |pmid= 1549121 |doi=
*cite journal | author=Chen IT, Dixit A, Rhoads DD, Roufa DJ |title=Homologous ribosomal proteins in bacteria, yeast, and humans. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=83 |issue= 18 |pages= 6907–11 |year= 1986 |pmid= 3529092 |doi=
*cite journal | author=Rhoads DD, Dixit A, Roufa DJ |title=Primary structure of human ribosomal protein S14 and the gene that encodes it. |journal=Mol. Cell. Biol. |volume=6 |issue= 8 |pages= 2774–83 |year= 1987 |pmid= 3785212 |doi=
*cite journal | author=Dana S, Wasmuth JJ |title=Selective linkage disruption in human-Chinese hamster cell hybrids: deletion mapping of the leuS, hexB, emtB, and chr genes on human chromosome 5. |journal=Mol. Cell. Biol. |volume=2 |issue= 10 |pages= 1220–8 |year= 1983 |pmid= 7177110 |doi=
*cite journal | author=Tasheva ES, Roufa DJ |title=Regulation of human RPS14 transcription by intronic antisense RNAs and ribosomal protein S14. |journal=Genes Dev. |volume=9 |issue= 3 |pages= 304–16 |year= 1995 |pmid= 7867928 |doi=
*cite journal | author=Matoba R, Okubo K, Hori N, "et al." |title=The addition of 5'-coding information to a 3'-directed cDNA library improves analysis of gene expression. |journal=Gene |volume=146 |issue= 2 |pages= 199–207 |year= 1994 |pmid= 8076819 |doi=
*cite journal | author=Vladimirov SN, Ivanov AV, Karpova GG, "et al." |title=Characterization of the human small-ribosomal-subunit proteins by N-terminal and internal sequencing, and mass spectrometry. |journal=Eur. J. Biochem. |volume=239 |issue= 1 |pages= 144–9 |year= 1996 |pmid= 8706699 |doi=
*cite journal | author=Martin-Nieto J, Roufa DJ |title=Functional analysis of human RPS14 null alleles. |journal=J. Cell. Sci. |volume=110 ( Pt 8) |issue= |pages= 955–63 |year= 1997 |pmid= 9152021 |doi=
*cite journal | author=Kenmochi N, Kawaguchi T, Rozen S, "et al." |title=A map of 75 human ribosomal protein genes. |journal=Genome Res. |volume=8 |issue= 5 |pages= 509–23 |year= 1998 |pmid= 9582194 |doi=
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Colland F, Jacq X, Trouplin V, "et al." |title=Functional proteomics mapping of a human signaling pathway. |journal=Genome Res. |volume=14 |issue= 7 |pages= 1324–32 |year= 2004 |pmid= 15231748 |doi= 10.1101/gr.2334104
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Yu Y, Ji H, Doudna JA, Leary JA |title=Mass spectrometric analysis of the human 40S ribosomal subunit: native and HCV IRES-bound complexes. |journal=Protein Sci. |volume=14 |issue= 6 |pages= 1438–46 |year= 2005 |pmid= 15883184 |doi= 10.1110/ps.041293005
*cite journal | author=Rual JF, Venkatesan K, Hao T, "et al." |title=Towards a proteome-scale map of the human protein-protein interaction network. |journal=Nature |volume=437 |issue= 7062 |pages= 1173–8 |year= 2005 |pmid= 16189514 |doi= 10.1038/nature04209
*cite journal | author=Lim J, Hao T, Shaw C, "et al." |title=A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration. |journal=Cell |volume=125 |issue= 4 |pages= 801–14 |year= 2006 |pmid= 16713569 |doi= 10.1016/j.cell.2006.03.032
*cite journal | author=Ewing RM, Chu P, Elisma F, "et al." |title=Large-scale mapping of human protein-protein interactions by mass spectrometry. |journal=Mol. Syst. Biol. |volume=3 |issue= |pages= 89 |year= 2007 |pmid= 17353931 |doi= 10.1038/msb4100134

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