RNF5

Ring finger protein 5, also known as RNF5, is a human gene.cite web | title = Entrez Gene: RNF5 ring finger protein 5| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=6048| accessdate = ]

PBB_Summary
section_title =
summary_text = The protein encoded by this gene contains a RING finger, which is a motif known to be involved in protein-protein interactions. This protein is a membrane-bound ubiquitin ligase. It can regulate cell motility by targeting paxillin ubiquitination and altering the distribution and localization of paxillin in cytoplasm and cell focal adhesions.cite web | title = Entrez Gene: RNF5 ring finger protein 5| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=6048| accessdate = ]

ee also

* RING finger domain

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Kendall E, Sargent CA, Campbell RD |title=Human major histocompatibility complex contains a new cluster of genes between the HLA-D and complement C4 loci. |journal=Nucleic Acids Res. |volume=18 |issue= 24 |pages= 7251–7 |year= 1991 |pmid= 2259622 |doi=
*cite journal | author=Bonaldo MF, Lennon G, Soares MB |title=Normalization and subtraction: two approaches to facilitate gene discovery. |journal=Genome Res. |volume=6 |issue= 9 |pages= 791–806 |year= 1997 |pmid= 8889548 |doi=
*cite journal | author=Kyushiki H, Kuga Y, Suzuki M, "et al." |title=Cloning, expression and mapping of a novel RING-finger gene (RNF5), a human homologue of a putative zinc-finger gene from Caenorhabditis elegans. |journal=Cytogenet. Cell Genet. |volume=79 |issue= 1-2 |pages= 114–7 |year= 1998 |pmid= 9533025 |doi=
*cite journal | author=Barritt DS, Pearn MT, Zisch AH, "et al." |title=The multi-PDZ domain protein MUPP1 is a cytoplasmic ligand for the membrane-spanning proteoglycan NG2. |journal=J. Cell. Biochem. |volume=79 |issue= 2 |pages= 213–24 |year= 2000 |pmid= 10967549 |doi=
*cite journal | author=Matsuda N, Suzuki T, Tanaka K, Nakano A |title=Rma1, a novel type of RING finger protein conserved from Arabidopsis to human, is a membrane-bound ubiquitin ligase. |journal=J. Cell. Sci. |volume=114 |issue= Pt 10 |pages= 1949–57 |year= 2001 |pmid= 11329381 |doi=
*cite journal | author=Pouly S, Prat A, Blain M, "et al." |title=NG2 immunoreactivity on human brain endothelial cells. |journal=Acta Neuropathol. |volume=102 |issue= 4 |pages= 313–20 |year= 2002 |pmid= 11603805 |doi=
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Didier C, Broday L, Bhoumik A, "et al." |title=RNF5, a RING finger protein that regulates cell motility by targeting paxillin ubiquitination and altered localization. |journal=Mol. Cell. Biol. |volume=23 |issue= 15 |pages= 5331–45 |year= 2003 |pmid= 12861019 |doi=
*cite journal | author=Mungall AJ, Palmer SA, Sims SK, "et al." |title=The DNA sequence and analysis of human chromosome 6. |journal=Nature |volume=425 |issue= 6960 |pages= 805–11 |year= 2003 |pmid= 14574404 |doi= 10.1038/nature02055
*cite journal | author=Xie T, Rowen L, Aguado B, "et al." |title=Analysis of the gene-dense major histocompatibility complex class III region and its comparison to mouse. |journal=Genome Res. |volume=13 |issue= 12 |pages= 2621–36 |year= 2004 |pmid= 14656967 |doi= 10.1101/gr.1736803
*cite journal | author=Lehner B, Semple JI, Brown SE, "et al." |title=Analysis of a high-throughput yeast two-hybrid system and its use to predict the function of intracellular proteins encoded within the human MHC class III region. |journal=Genomics |volume=83 |issue= 1 |pages= 153–67 |year= 2004 |pmid= 14667819 |doi=
*cite journal | author=Liu AM, Wong YH |title=G16-mediated activation of nuclear factor kappaB by the adenosine A1 receptor involves c-Src, protein kinase C, and ERK signaling. |journal=J. Biol. Chem. |volume=279 |issue= 51 |pages= 53196–204 |year= 2005 |pmid= 15485865 |doi= 10.1074/jbc.M410196200
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Barrios-Rodiles M, Brown KR, Ozdamar B, "et al." |title=High-throughput mapping of a dynamic signaling network in mammalian cells. |journal=Science |volume=307 |issue= 5715 |pages= 1621–5 |year= 2005 |pmid= 15761153 |doi= 10.1126/science.1105776
*cite journal | author=Zhang Y, Higashide W, Dai S, "et al." |title=Recognition and ubiquitination of Salmonella type III effector SopA by a ubiquitin E3 ligase, HsRMA1. |journal=J. Biol. Chem. |volume=280 |issue= 46 |pages= 38682–8 |year= 2006 |pmid= 16176924 |doi= 10.1074/jbc.M506309200
*cite journal | author=Rual JF, Venkatesan K, Hao T, "et al." |title=Towards a proteome-scale map of the human protein-protein interaction network. |journal=Nature |volume=437 |issue= 7062 |pages= 1173–8 |year= 2005 |pmid= 16189514 |doi= 10.1038/nature04209
*cite journal | author=Younger JM, Chen L, Ren HY, "et al." |title=Sequential quality-control checkpoints triage misfolded cystic fibrosis transmembrane conductance regulator. |journal=Cell |volume=126 |issue= 3 |pages= 571–82 |year= 2006 |pmid= 16901789 |doi= 10.1016/j.cell.2006.06.041
*cite journal | author=Bromberg KD, Kluger HM, Delaunay A, "et al." |title=Increased expression of the E3 ubiquitin ligase RNF5 is associated with decreased survival in breast cancer. |journal=Cancer Res. |volume=67 |issue= 17 |pages= 8172–9 |year= 2007 |pmid= 17804730 |doi= 10.1158/0008-5472.CAN-07-0045

External links

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