REG3A

Regenerating islet-derived 3 alpha, also known as REG3A, is a human gene.cite web | title = Entrez Gene: REG3A regenerating islet-derived 3 alpha| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=5068| accessdate = ]

PBB_Summary
section_title =
summary_text = This gene encodes a pancreatic secretory protein that may be involved in cell proliferation or differentiation. It has similarity to the C-type lectin superfamily. The enhanced expression of this gene is observed during pancreatic inflammation and liver carcinogenesis. Multiple alternatively spliced transcript variants encoding the same protein have been described for this gene but the full length nature of some transcripts is not yet known.cite web | title = Entrez Gene: REG3A regenerating islet-derived 3 alpha| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=5068| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Lasserre C, Christa L, Simon MT, "et al." |title=A novel gene (HIP) activated in human primary liver cancer. |journal=Cancer Res. |volume=52 |issue= 18 |pages= 5089–95 |year= 1992 |pmid= 1325291 |doi=
*cite journal | author=Orelle B, Keim V, Masciotra L, "et al." |title=Human pancreatitis-associated protein. Messenger RNA cloning and expression in pancreatic diseases. |journal=J. Clin. Invest. |volume=90 |issue= 6 |pages= 2284–91 |year= 1993 |pmid= 1469087 |doi=
*cite journal | author=Itoh T, Teraoka H |title=Cloning and tissue-specific expression of cDNAs for the human and mouse homologues of rat pancreatitis-associated protein (PAP). |journal=Biochim. Biophys. Acta |volume=1172 |issue= 1-2 |pages= 184–6 |year= 1993 |pmid= 7679928 |doi=
*cite journal | author=Itoh T, Sawabu N, Motoo Y, "et al." |title=The human pancreatitis-associated protein (PAP)-encoding gene generates multiple transcripts through alternative use of 5' exons. |journal=Gene |volume=155 |issue= 2 |pages= 283–7 |year= 1995 |pmid= 7721106 |doi=
*cite journal | author=Lasserre C, Simon MT, Ishikawa H, "et al." |title=Structural organization and chromosomal localization of a human gene (HIP/PAP) encoding a C-type lectin overexpressed in primary liver cancer. |journal=Eur. J. Biochem. |volume=224 |issue= 1 |pages= 29–38 |year= 1994 |pmid= 8076648 |doi=
*cite journal | author=Dusetti NJ, Frigerio JM, Fox MF, "et al." |title=Molecular cloning, genomic organization, and chromosomal localization of the human pancreatitis-associated protein (PAP) gene. |journal=Genomics |volume=19 |issue= 1 |pages= 108–14 |year= 1994 |pmid= 8188210 |doi= 10.1006/geno.1994.1019
*cite journal | author=Christa L, Carnot F, Simon MT, "et al." |title=HIP/PAP is an adhesive protein expressed in hepatocarcinoma, normal Paneth, and pancreatic cells. |journal=Am. J. Physiol. |volume=271 |issue= 6 Pt 1 |pages= G993–1002 |year= 1997 |pmid= 8997243 |doi=
*cite journal | author=Rafaeloff R, Pittenger GL, Barlow SW, "et al." |title=Cloning and sequencing of the pancreatic islet neogenesis associated protein (INGAP) gene and its expression in islet neogenesis in hamsters. |journal=J. Clin. Invest. |volume=99 |issue= 9 |pages= 2100–9 |year= 1997 |pmid= 9151782 |doi=
*cite journal | author=Bödeker H, Keim V, Fiedler F, "et al." |title=PAP I interacts with itself, PAP II, PAP III, and lithostathine/regIalpha. |journal=Mol. Cell Biol. Res. Commun. |volume=2 |issue= 3 |pages= 150–4 |year= 2000 |pmid= 10662590 |doi= 10.1006/mcbr.1999.0166
*cite journal | author=Graf R, Schiesser M, Scheele GA, "et al." |title=A family of 16-kDa pancreatic secretory stress proteins form highly organized fibrillar structures upon tryptic activation. |journal=J. Biol. Chem. |volume=276 |issue= 24 |pages= 21028–38 |year= 2001 |pmid= 11278730 |doi= 10.1074/jbc.M010717200
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Simon MT, Pauloin A, Normand G, "et al." |title=HIP/PAP stimulates liver regeneration after partial hepatectomy and combines mitogenic and anti-apoptotic functions through the PKA signaling pathway. |journal=FASEB J. |volume=17 |issue= 11 |pages= 1441–50 |year= 2003 |pmid= 12890698 |doi= 10.1096/fj.02-1013com
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Lieu HT, Batteux F, Simon MT, "et al." |title=HIP/PAP accelerates liver regeneration and protects against acetaminophen injury in mice. |journal=Hepatology |volume=42 |issue= 3 |pages= 618–26 |year= 2005 |pmid= 16116631 |doi= 10.1002/hep.20845
*cite journal | author=Rual JF, Venkatesan K, Hao T, "et al." |title=Towards a proteome-scale map of the human protein-protein interaction network. |journal=Nature |volume=437 |issue= 7062 |pages= 1173–8 |year= 2005 |pmid= 16189514 |doi= 10.1038/nature04209
*cite journal | author=Cash HL, Whitham CV, Behrendt CL, Hooper LV |title=Symbiotic bacteria direct expression of an intestinal bactericidal lectin. |journal=Science |volume=313 |issue= 5790 |pages= 1126–30 |year= 2006 |pmid= 16931762 |doi= 10.1126/science.1127119
*cite journal | author=Ho MR, Lou YC, Lin WC, "et al." |title=Human pancreatitis-associated protein forms fibrillar aggregates with a native-like conformation. |journal=J. Biol. Chem. |volume=281 |issue= 44 |pages= 33566–76 |year= 2006 |pmid= 16963458 |doi= 10.1074/jbc.M604513200

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