COTL1

Coactosin-like 1 (Dictyostelium), also known as COTL1, is a human gene.cite web | title = Entrez Gene: COTL1 coactosin-like 1 (Dictyostelium)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=23406| accessdate = ]

PBB_Summary
section_title =
summary_text = This gene encodes one of the numerous actin-binding proteins which regulate the actin cytoskeleton. This protein binds F-actin, and also interacts with 5-lipoxygenase, which is the first committed enzyme in leukotriene biosynthesis. Although this gene has been reported to map to chromosome 17 in the Smith-Magenis syndrome region, the best alignments for this gene are to chromosome 16. The Smith-Magenis syndrome region is the site of two related pseudogenes.cite web | title = Entrez Gene: COTL1 coactosin-like 1 (Dictyostelium)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=23406| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Wu C, Friedlander P, Lamoureux C, "et al." |title=cDNA clones contain autonomous replication activity. |journal=Biochim. Biophys. Acta |volume=1174 |issue= 3 |pages= 241–57 |year= 1993 |pmid= 7690594 |doi=
*cite journal | author=Chen KS, Manian P, Koeuth T, "et al." |title=Homologous recombination of a flanking repeat gene cluster is a mechanism for a common contiguous gene deletion syndrome. |journal=Nat. Genet. |volume=17 |issue= 2 |pages= 154–63 |year= 1997 |pmid= 9326934 |doi= 10.1038/ng1097-154
*cite journal | author=Provost P, Samuelsson B, Rådmark O |title=Interaction of 5-lipoxygenase with cellular proteins. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=96 |issue= 5 |pages= 1881–5 |year= 1999 |pmid= 10051563 |doi=
*cite journal | author=Provost P, Doucet J, Hammarberg T, "et al." |title=5-Lipoxygenase interacts with coactosin-like protein. |journal=J. Biol. Chem. |volume=276 |issue= 19 |pages= 16520–7 |year= 2001 |pmid= 11297527 |doi= 10.1074/jbc.M011205200
*cite journal | author=Provost P, Doucet J, Stock A, "et al." |title=Coactosin-like protein, a human F-actin-binding protein: critical role of lysine-75. |journal=Biochem. J. |volume=359 |issue= Pt 2 |pages= 255–63 |year= 2001 |pmid= 11583571 |doi=
*cite journal | author=Nakatsura T, Senju S, Ito M, "et al." |title=Cellular and humoral immune responses to a human pancreatic cancer antigen, coactosin-like protein, originally defined by the SEREX method. |journal=Eur. J. Immunol. |volume=32 |issue= 3 |pages= 826–36 |year= 2002 |pmid= 11870627 |doi=
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Gevaert K, Goethals M, Martens L, "et al." |title=Exploring proteomes and analyzing protein processing by mass spectrometric identification of sorted N-terminal peptides. |journal=Nat. Biotechnol. |volume=21 |issue= 5 |pages= 566–9 |year= 2004 |pmid= 12665801 |doi= 10.1038/nbt810
*cite journal | author=Ota T, Suzuki Y, Nishikawa T, "et al." |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285
*cite journal | author=Dai H, Wu J, Xu Y, "et al." |title=1H, 13C and 15N resonance assignments and the secondary structures of human coactosin like protein (hCLP) D123N. |journal=J. Biomol. NMR |volume=29 |issue= 3 |pages= 455–6 |year= 2005 |pmid= 15213466 |doi= 10.1023/B:JNMR.0000032550.18424.aa
*cite journal | author=Liu L, Wang Y, Zhang P, "et al." |title=Expression, purification and preliminary crystallographic studies of human coactosin-like protein. |journal=Acta Crystallogr. D Biol. Crystallogr. |volume=60 |issue= Pt 9 |pages= 1651–3 |year= 2005 |pmid= 15333945 |doi= 10.1107/S0907444904016701
*cite journal | author=Li X, Liu X, Lou Z, "et al." |title=Crystal structure of human coactosin-like protein at 1.9 A resolution. |journal=Protein Sci. |volume=13 |issue= 11 |pages= 2845–51 |year= 2005 |pmid= 15459340 |doi= 10.1110/ps.04937304
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Li X, Liu X, Zhao Q, "et al." |title=Crystallization and preliminary crystallographic studies of human coactosin-like protein (CLP). |journal=Acta Crystallogr. D Biol. Crystallogr. |volume=60 |issue= Pt 12 Pt 2 |pages= 2387–8 |year= 2005 |pmid= 15583396 |doi= 10.1107/S0907444904028112
*cite journal | author=Gevaert K, Staes A, Van Damme J, "et al." |title=Global phosphoproteome analysis on human HepG2 hepatocytes using reversed-phase diagonal LC. |journal=Proteomics |volume=5 |issue= 14 |pages= 3589–99 |year= 2006 |pmid= 16097034 |doi= 10.1002/pmic.200401217
*cite journal | author=Rakonjac M, Fischer L, Provost P, "et al." |title=Coactosin-like protein supports 5-lipoxygenase enzyme activity and up-regulates leukotriene A4 production. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=103 |issue= 35 |pages= 13150–5 |year= 2006 |pmid= 16924104 |doi= 10.1073/pnas.0605150103
*cite journal | author=Dai H, Huang W, Xu J, "et al." |title=Binding model of human coactosin-like protein with filament actin revealed by mutagenesis. |journal=Biochim. Biophys. Acta |volume=1764 |issue= 11 |pages= 1688–700 |year= 2006 |pmid= 17070122 |doi= 10.1016/j.bbapap.2006.06.017

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