- AMY2B
Amylase, alpha 2B (pancreatic), also known as AMY2B, is a human
gene .cite web | title = Entrez Gene: AMY2B amylase, alpha 2B (pancreatic)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=280| accessdate = ]PBB_Summary
section_title =
summary_text = Amylases are secreted proteins that hydrolyze 1,4-alpha-glucoside bonds in oligosaccharides and polysaccharides, and thus catalyze the first step in digestion of dietary starch and glycogen. The human genome has a cluster of several amylase genes that are expressed at high levels in either salivary gland or pancreas. This gene encodes an amylase isoenzyme produced by the pancreas.cite web | title = Entrez Gene: AMY2B amylase, alpha 2B (pancreatic)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=280| accessdate = ]References
Further reading
PBB_Further_reading
citations =
*cite journal | author=Kaczmarek MJ, Rosenmund H |title=The action of human pancreatic and salivary isoamylases on starch and glycogen. |journal=Clin. Chim. Acta |volume=79 |issue= 1 |pages= 69–73 |year= 1977 |pmid= 890964 |doi=
*cite journal | author=Groot PC, Mager WH, Henriquez NV, "et al." |title=Evolution of the human alpha-amylase multigene family through unequal, homologous, and inter- and intrachromosomal crossovers. |journal=Genomics |volume=8 |issue= 1 |pages= 97–105 |year= 1991 |pmid= 2081604 |doi=
*cite journal | author=Yokouchi H, Horii A, Emi M, "et al." |title=Cloning and characterization of a third type of human alpha-amylase gene, AMY2B. |journal=Gene |volume=90 |issue= 2 |pages= 281–6 |year= 1990 |pmid= 2401405 |doi=
*cite journal | author=Gumucio DL, Wiebauer K, Caldwell RM, "et al." |title=Concerted evolution of human amylase genes. |journal=Mol. Cell. Biol. |volume=8 |issue= 3 |pages= 1197–205 |year= 1988 |pmid= 2452973 |doi=
*cite journal | author=Samuelson LC, Wiebauer K, Gumucio DL, Meisler MH |title=Expression of the human amylase genes: recent origin of a salivary amylase promoter from an actin pseudogene. |journal=Nucleic Acids Res. |volume=16 |issue= 17 |pages= 8261–76 |year= 1988 |pmid= 2458567 |doi=
*cite journal | author=Tomita N, Horii A, Doi S, "et al." |title=A novel type of human alpha-amylase produced in lung carcinoid tumor. |journal=Gene |volume=76 |issue= 1 |pages= 11–8 |year= 1989 |pmid= 2701942 |doi=
*cite journal | author=Groot PC, Bleeker MJ, Pronk JC, "et al." |title=The human alpha-amylase multigene family consists of haplotypes with variable numbers of genes. |journal=Genomics |volume=5 |issue= 1 |pages= 29–42 |year= 1989 |pmid= 2788608 |doi=
*cite journal | author=Groot PC, Bleeker MJ, Pronk JC, "et al." |title=Human pancreatic amylase is encoded by two different genes. |journal=Nucleic Acids Res. |volume=16 |issue= 10 |pages= 4724 |year= 1988 |pmid= 3260028 |doi=
*cite journal | author=Tricoli JV, Shows TB |title=Regional assignment of human amylase (AMY) to p22----p21 of chromosome 1. |journal=Somat. Cell Mol. Genet. |volume=10 |issue= 2 |pages= 205–10 |year= 1984 |pmid= 6608795 |doi=
*cite journal | author=Omichi K, Hase S |title=Identification of the characteristic amino-acid sequence for human alpha-amylase encoded by the AMY2B gene. |journal=Biochim. Biophys. Acta |volume=1203 |issue= 2 |pages= 224–9 |year= 1994 |pmid= 8268204 |doi=
*cite journal | author=Nagase T, Nakayama M, Nakajima D, "et al." |title=Prediction of the coding sequences of unidentified human genes. XX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. |journal=DNA Res. |volume=8 |issue= 2 |pages= 85–95 |year= 2001 |pmid= 11347906 |doi=
*cite journal | author=Aughsteen AA |title=A comparative immunohistochemical study on amylase localization in the rat and human exocrine pancreas. |journal=Saudi medical journal |volume=22 |issue= 5 |pages= 410–5 |year= 2001 |pmid= 11376382 |doi=
*cite journal | author=Koyama I, Komine S, Iino N, "et al." |title=alpha-Amylase expressed in human liver is encoded by the AMY-2B gene identified in tumorous tissues. |journal=Clin. Chim. Acta |volume=309 |issue= 1 |pages= 73–83 |year= 2001 |pmid= 11408008 |doi=
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Ota T, Suzuki Y, Nishikawa T, "et al." |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285
*cite journal | author=Iafrate AJ, Feuk L, Rivera MN, "et al." |title=Detection of large-scale variation in the human genome. |journal=Nat. Genet. |volume=36 |issue= 9 |pages= 949–51 |year= 2004 |pmid= 15286789 |doi= 10.1038/ng1416
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504PBB_Controls
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