PPAN

Peter pan homolog (Drosophila), also known as PPAN, is a human gene.cite web | title = Entrez Gene: PPAN peter pan homolog (Drosophila)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=56342| accessdate = ]

PBB_Summary
section_title =
summary_text = The protein encoded by this gene is an evolutionarily conserved protein similar to yeast SSF1 as well as to the gene product of the Drosophila gene peter pan (ppan). SSF1 is known to be involved in the second step of mRNA splicing. Both SSF1 and ppan are essential for cell growth and proliferation. This gene was found to cotranscript with P2RY11/P2Y(11), an immediate downstream gene on the chromosome that encodes an ATP receptor. The chimeric transcripts of this gene and P2RY11 were found to be ubiquitously present and regulated during granulocytic differentiation. Exogenous expression of this gene was reported to reduce the anchorage-independent growth of some tumor cells.cite web | title = Entrez Gene: PPAN peter pan homolog (Drosophila)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=56342| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Communi D, Govaerts C, Parmentier M, Boeynaems JM |title=Cloning of a human purinergic P2Y receptor coupled to phospholipase C and adenylyl cyclase. |journal=J. Biol. Chem. |volume=272 |issue= 51 |pages= 31969–73 |year= 1998 |pmid= 9405388 |doi=
*cite journal | author=Migeon JC, Garfinkel MS, Edgar BA |title=Cloning and characterization of peter pan, a novel Drosophila gene required for larval growth. |journal=Mol. Biol. Cell |volume=10 |issue= 6 |pages= 1733–44 |year= 1999 |pmid= 10359593 |doi=
*cite journal | author=Welch PJ, Marcusson EG, Li QX, "et al." |title=Identification and validation of a gene involved in anchorage-independent cell growth control using a library of randomized hairpin ribozymes. |journal=Genomics |volume=66 |issue= 3 |pages= 274–83 |year= 2000 |pmid= 10873382 |doi= 10.1006/geno.2000.6230
*cite journal | author=Suarez-Huerta N, Boeynaems JM, Communi D |title=Cloning, genomic organization, and tissue distribution of human Ssf-1. |journal=Biochem. Biophys. Res. Commun. |volume=275 |issue= 1 |pages= 37–42 |year= 2000 |pmid= 10944437 |doi= 10.1006/bbrc.2000.3259
*cite journal | author=Communi D, Suarez-Huerta N, Dussossoy D, "et al." |title=Cotranscription and intergenic splicing of human P2Y11 and SSF1 genes. |journal=J. Biol. Chem. |volume=276 |issue= 19 |pages= 16561–6 |year= 2001 |pmid= 11278528 |doi= 10.1074/jbc. M009609200
*cite journal | author=Andersen JS, Lyon CE, Fox AH, "et al." |title=Directed proteomic analysis of the human nucleolus. |journal=Curr. Biol. |volume=12 |issue= 1 |pages= 1–11 |year= 2002 |pmid= 11790298 |doi=
*cite journal | author=Duhant X, Schandené L, Bruyns C, "et al." |title=Extracellular adenine nucleotides inhibit the activation of human CD4+ T lymphocytes. |journal=J. Immunol. |volume=169 |issue= 1 |pages= 15–21 |year= 2002 |pmid= 12077223 |doi=
*cite journal | author=Scherl A, Couté Y, Déon C, "et al." |title=Functional proteomic analysis of human nucleolus. |journal=Mol. Biol. Cell |volume=13 |issue= 11 |pages= 4100–9 |year= 2003 |pmid= 12429849 |doi= 10.1091/mbc. E02-05-0271
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Beausoleil SA, Jedrychowski M, Schwartz D, "et al." |title=Large-scale characterization of HeLa cell nuclear phosphoproteins. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=101 |issue= 33 |pages= 12130–5 |year= 2004 |pmid= 15302935 |doi= 10.1073/pnas.0404720101
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Nousiainen M, Silljé HH, Sauer G, "et al." |title=Phosphoproteome analysis of the human mitotic spindle. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=103 |issue= 14 |pages= 5391–6 |year= 2006 |pmid= 16565220 |doi= 10.1073/pnas.0507066103
*cite journal | author=Beausoleil SA, Villén J, Gerber SA, "et al." |title=A probability-based approach for high-throughput protein phosphorylation analysis and site localization. |journal=Nat. Biotechnol. |volume=24 |issue= 10 |pages= 1285–92 |year= 2006 |pmid= 16964243 |doi= 10.1038/nbt1240
*cite journal | author=Olsen JV, Blagoev B, Gnad F, "et al." |title=Global, "in vivo", and site-specific phosphorylation dynamics in signaling networks. |journal=Cell |volume=127 |issue= 3 |pages= 635–48 |year= 2006 |pmid= 17081983 |doi= 10.1016/j.cell.2006.09.026
*cite journal | author=Ewing RM, Chu P, Elisma F, "et al." |title=Large-scale mapping of human protein-protein interactions by mass spectrometry. |journal=Mol. Syst. Biol. |volume=3 |issue= |pages= 89 |year= 2007 |pmid= 17353931 |doi= 10.1038/msb4100134

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