POLQ

POLQ

Polymerase (DNA directed), theta, also known as POLQ, is a human gene.cite web | title = Entrez Gene: POLQ polymerase (DNA directed), theta| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=10721| accessdate = ]

PBB_Summary
section_title =
summary_text =

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Robertson NG, Khetarpal U, Gutiérrez-Espeleta GA, "et al." |title=Isolation of novel and known genes from a human fetal cochlear cDNA library using subtractive hybridization and differential screening. |journal=Genomics |volume=23 |issue= 1 |pages= 42–50 |year= 1995 |pmid= 7829101 |doi= 10.1006/geno.1994.1457
*cite journal | author=Sharief FS, Vojta PJ, Ropp PA, Copeland WC |title=Cloning and chromosomal mapping of the human DNA polymerase theta (POLQ), the eighth human DNA polymerase. |journal=Genomics |volume=59 |issue= 1 |pages= 90–6 |year= 1999 |pmid= 10395804 |doi= 10.1006/geno.1999.5843
*cite journal | author=Maga G, Shevelev I, Ramadan K, "et al." |title=DNA polymerase theta purified from human cells is a high-fidelity enzyme. |journal=J. Mol. Biol. |volume=319 |issue= 2 |pages= 359–69 |year= 2002 |pmid= 12051913 |doi= 10.1016/S0022-2836(02)00325-X
*cite journal | author=Seki M, Marini F, Wood RD |title=POLQ (Pol theta), a DNA polymerase and DNA-dependent ATPase in human cells. |journal=Nucleic Acids Res. |volume=31 |issue= 21 |pages= 6117–26 |year= 2003 |pmid= 14576298 |doi=
*cite journal | author=Kawamura K, Bahar R, Seimiya M, "et al." |title=DNA polymerase theta is preferentially expressed in lymphoid tissues and upregulated in human cancers. |journal=Int. J. Cancer |volume=109 |issue= 1 |pages= 9–16 |year= 2004 |pmid= 14735462 |doi= 10.1002/ijc.11666
*cite journal | author=Suzuki Y, Yamashita R, Shirota M, "et al." |title=Sequence comparison of human and mouse genes reveals a homologous block structure in the promoter regions. |journal=Genome Res. |volume=14 |issue= 9 |pages= 1711–8 |year= 2004 |pmid= 15342556 |doi= 10.1101/gr.2435604
*cite journal | author=Seki M, Masutani C, Yang LW, "et al." |title=High-efficiency bypass of DNA damage by human DNA polymerase Q. |journal=EMBO J. |volume=23 |issue= 22 |pages= 4484–94 |year= 2005 |pmid= 15496986 |doi= 10.1038/sj.emboj.7600424
*cite journal | author=Chiapperino D, Cai M, Sayer JM, "et al." |title=Error-prone translesion synthesis by human DNA polymerase eta on DNA-containing deoxyadenosine adducts of 7,8-dihydroxy-9,10-epoxy-7,8,9,10-tetrahydrobenzo [a] pyrene. |journal=J. Biol. Chem. |volume=280 |issue= 48 |pages= 39684–92 |year= 2006 |pmid= 16188888 |doi= 10.1074/jbc.M508008200
*cite journal | author=Zan H, Shima N, Xu Z, "et al." |title=The translesion DNA polymerase theta plays a dominant role in immunoglobulin gene somatic hypermutation. |journal=EMBO J. |volume=24 |issue= 21 |pages= 3757–69 |year= 2005 |pmid= 16222339 |doi= 10.1038/sj.emboj.7600833
*cite journal | author=Cruet-Hennequart S, Coyne S, Glynn MT, "et al." |title=UV-induced RPA phosphorylation is increased in the absence of DNA polymerase eta and requires DNA-PK. |journal=DNA Repair (Amst.) |volume=5 |issue= 4 |pages= 491–504 |year= 2006 |pmid= 16520097 |doi= 10.1016/j.dnarep.2006.01.008
*cite journal | author=Chen YW, Cleaver JE, Hanaoka F, "et al." |title=A novel role of DNA polymerase eta in modulating cellular sensitivity to chemotherapeutic agents. |journal=Mol. Cancer Res. |volume=4 |issue= 4 |pages= 257–65 |year= 2006 |pmid= 16603639 |doi= 10.1158/1541-7786.MCR-05-0118
*cite journal | author=Yuasa MS, Masutani C, Hirano A, "et al." |title=A human DNA polymerase eta complex containing Rad18, Rad6 and Rev1; proteomic analysis and targeting of the complex to the chromatin-bound fraction of cells undergoing replication fork arrest. |journal=Genes Cells |volume=11 |issue= 7 |pages= 731–44 |year= 2006 |pmid= 16824193 |doi= 10.1111/j.1365-2443.2006.00974.x
*cite journal | author=Choi JY, Stover JS, Angel KC, "et al." |title=Biochemical basis of genotoxicity of heterocyclic arylamine food mutagens: Human DNA polymerase eta selectively produces a two-base deletion in copying the N2-guanyl adduct of 2-amino-3-methylimidazo [4,5-f] quinoline but not the C8 adduct at the NarI G3 site. |journal=J. Biol. Chem. |volume=281 |issue= 35 |pages= 25297–306 |year= 2006 |pmid= 16835218 |doi= 10.1074/jbc.M605699200
*cite journal | author=Kino K, Ito N, Sugasawa K, "et al." |title=Translesion synthesis by human DNA polymerase eta across oxidative products of guanine. |journal=Nucleic Acids Symp Ser (Oxf) |volume= |issue= 48 |pages= 171–2 |year= 2007 |pmid= 17150533 |doi= 10.1093/nass/48.1.171
*cite journal | author=Ewing RM, Chu P, Elisma F, "et al." |title=Large-scale mapping of human protein-protein interactions by mass spectrometry. |journal=Mol. Syst. Biol. |volume=3 |issue= |pages= 89 |year= 2007 |pmid= 17353931 |doi= 10.1038/msb4100134

PBB_Controls
update_page = yes
require_manual_inspection = no
update_protein_box = yes
update_summary = yes
update_citations = yes


Wikimedia Foundation. 2010.

Игры ⚽ Нужна курсовая?

Share the article and excerpts

Direct link
Do a right-click on the link above
and select “Copy Link”