TSC22D3

TSC22 domain family, member 3, also known as TSC22D3, is a human gene.cite web | title = Entrez Gene: TSC22D3 TSC22 domain family, member 3| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=1831| accessdate = ]

PBB_Summary
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summary_text = The protein encoded by this gene shares significant sequence identity with the murine TSC-22 and Drosophila shs, both of which are leucine zipper proteins, that function as transcriptional regulators. The expression of this gene is stimulated by glucocorticoids and interleukin 10, and it appears to play a key role in the anti-inflammatory and immunosuppressive effects of this steroid and chemokine. Transcript variants encoding different isoforms have been identified for this gene.cite web | title = Entrez Gene: TSC22D3 TSC22 domain family, member 3| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=1831| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Andersson B, Wentland MA, Ricafrente JY, "et al." |title=A "double adaptor" method for improved shotgun library construction. |journal=Anal. Biochem. |volume=236 |issue= 1 |pages= 107–13 |year= 1996 |pmid= 8619474 |doi= 10.1006/abio.1996.0138
*cite journal | author=Vogel P, Mägert HJ, Cieslak A, "et al." |title=hDIP--a potential transcriptional regulator related to murine TSC-22 and Drosophila shortsighted (shs)--is expressed in a large number of human tissues. |journal=Biochim. Biophys. Acta |volume=1309 |issue= 3 |pages= 200–4 |year= 1997 |pmid= 8982256 |doi=
*cite journal | author=Yu W, Andersson B, Worley KC, "et al." |title=Large-scale concatenation cDNA sequencing. |journal=Genome Res. |volume=7 |issue= 4 |pages= 353–8 |year= 1997 |pmid= 9110174 |doi=
*cite journal | author=Wiemann S, Weil B, Wellenreuther R, "et al." |title=Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs. |journal=Genome Res. |volume=11 |issue= 3 |pages= 422–35 |year= 2001 |pmid= 11230166 |doi= 10.1101/gr.154701
*cite journal | author=Cannarile L, Zollo O, D'Adamio F, "et al." |title=Cloning, chromosomal assignment and tissue distribution of human GILZ, a glucocorticoid hormone-induced gene. |journal=Cell Death Differ. |volume=8 |issue= 2 |pages= 201–3 |year= 2001 |pmid= 11313722 |doi= 10.1038/sj/cdd/4400798
*cite journal | author=Mittelstadt PR, Ashwell JD |title=Inhibition of AP-1 by the glucocorticoid-inducible protein GILZ. |journal=J. Biol. Chem. |volume=276 |issue= 31 |pages= 29603–10 |year= 2001 |pmid= 11397794 |doi= 10.1074/jbc.M101522200
*cite journal | author=Ayroldi E, Migliorati G, Bruscoli S, "et al." |title=Modulation of T-cell activation by the glucocorticoid-induced leucine zipper factor via inhibition of nuclear factor kappaB. |journal=Blood |volume=98 |issue= 3 |pages= 743–53 |year= 2001 |pmid= 11468175 |doi=
*cite journal | author=Ayroldi E, Zollo O, Macchiarulo A, "et al." |title=Glucocorticoid-induced leucine zipper inhibits the Raf-extracellular signal-regulated kinase pathway by binding to Raf-1. |journal=Mol. Cell. Biol. |volume=22 |issue= 22 |pages= 7929–41 |year= 2002 |pmid= 12391160 |doi=
*cite journal | author=Berrebi D, Bruscoli S, Cohen N, "et al." |title=Synthesis of glucocorticoid-induced leucine zipper (GILZ) by macrophages: an anti-inflammatory and immunosuppressive mechanism shared by glucocorticoids and IL-10. |journal=Blood |volume=101 |issue= 2 |pages= 729–38 |year= 2003 |pmid= 12393603 |doi= 10.1182/blood-2002-02-0538
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Shi X, Shi W, Li Q, "et al." |title=A glucocorticoid-induced leucine-zipper protein, GILZ, inhibits adipogenesis of mesenchymal cells. |journal=EMBO Rep. |volume=4 |issue= 4 |pages= 374–80 |year= 2003 |pmid= 12671681 |doi= 10.1038/sj.embor.embor805
*cite journal | author=Ota T, Suzuki Y, Nishikawa T, "et al." |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285
*cite journal | author=Asselin-Labat ML, David M, Biola-Vidamment A, "et al." |title=GILZ, a new target for the transcription factor FoxO3, protects T lymphocytes from interleukin-2 withdrawal-induced apoptosis. |journal=Blood |volume=104 |issue= 1 |pages= 215–23 |year= 2004 |pmid= 15031210 |doi= 10.1182/blood-2003-12-4295
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Asselin-Labat ML, Biola-Vidamment A, Kerbrat S, "et al." |title=FoxO3 mediates antagonistic effects of glucocorticoids and interleukin-2 on glucocorticoid-induced leucine zipper expression. |journal=Mol. Endocrinol. |volume=19 |issue= 7 |pages= 1752–64 |year= 2005 |pmid= 15705665 |doi= 10.1210/me.2004-0206
*cite journal | author=Rual JF, Venkatesan K, Hao T, "et al." |title=Towards a proteome-scale map of the human protein-protein interaction network. |journal=Nature |volume=437 |issue= 7062 |pages= 1173–8 |year= 2005 |pmid= 16189514 |doi= 10.1038/nature04209
*cite journal | author=Soundararajan R, Zhang TT, Wang J, "et al." |title=A novel role for glucocorticoid-induced leucine zipper protein in epithelial sodium channel-mediated sodium transport. |journal=J. Biol. Chem. |volume=280 |issue= 48 |pages= 39970–81 |year= 2006 |pmid= 16216878 |doi= 10.1074/jbc.M508658200
*cite journal | author=Hamdi H, Godot V, Maillot MC, "et al." |title=Induction of antigen-specific regulatory T lymphocytes by human dendritic cells expressing the glucocorticoid-induced leucine zipper. |journal=Blood |volume=110 |issue= 1 |pages= 211–9 |year= 2007 |pmid= 17356131 |doi= 10.1182/blood-2006-10-052506

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