ZHX1

PBB|geneid=11244

Zinc fingers and homeoboxes 1, also known as ZHX1, is a human gene.cite web | title = Entrez Gene: ZHX1 zinc fingers and homeoboxes 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=11244| accessdate = ]

PBB_Summary
section_title =
summary_text = The members of the zinc fingers and homeoboxes gene family are nuclear homodimeric transcriptional repressors that interact with the A subunit of nuclear factor-Y (NF-YA) and contain two C2H2-type zinc fingers and five homeobox DNA-binding domains. This gene encodes member 1 of this gene family. In addition to forming homodimers, this protein heterodimerizes with members 2 and 3 of the zinc fingers and homeoboxes family. Alternative splicing results in multiple transcript variants encoding the same protein.cite web | title = Entrez Gene: ZHX1 zinc fingers and homeoboxes 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=11244| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Yamada K, Printz RL, Osawa H, Granner DK |title=Human ZHX1: cloning, chromosomal location, and interaction with transcription factor NF-Y. |journal=Biochem. Biophys. Res. Commun. |volume=261 |issue= 3 |pages= 614–21 |year= 1999 |pmid= 10441475 |doi= 10.1006/bbrc.1999.1087
*cite journal | author=Yamada K, Osawa H, Granner DK |title=Identification of proteins that interact with NF-YA. |journal=FEBS Lett. |volume=460 |issue= 1 |pages= 41–5 |year= 1999 |pmid= 10571058 |doi=
*cite journal | author=Hirano S, Yamada K, Kawata H, "et al." |title=Rat zinc-fingers and homeoboxes 1 (ZHX1), a nuclear factor-YA-interacting nuclear protein, forms a homodimer. |journal=Gene |volume=290 |issue= 1-2 |pages= 107–14 |year= 2002 |pmid= 12062805 |doi=
*cite journal | author=Yamada K, Kawata H, Matsuura K, "et al." |title=Functional analysis and the molecular dissection of zinc-fingers and homeoboxes 1 (ZHX1). |journal=Biochem. Biophys. Res. Commun. |volume=297 |issue= 2 |pages= 368–74 |year= 2002 |pmid= 12237128 |doi=
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Yamada K, Kawata H, Shou Z, "et al." |title=Analysis of zinc-fingers and homeoboxes (ZHX)-1-interacting proteins: molecular cloning and characterization of a member of the ZHX family, ZHX3. |journal=Biochem. J. |volume=373 |issue= Pt 1 |pages= 167–78 |year= 2003 |pmid= 12659632 |doi= 10.1042/BJ20021866
*cite journal | author=Kawata H, Yamada K, Shou Z, "et al." |title=Zinc-fingers and homeoboxes (ZHX) 2, a novel member of the ZHX family, functions as a transcriptional repressor. |journal=Biochem. J. |volume=373 |issue= Pt 3 |pages= 747–57 |year= 2003 |pmid= 12741956 |doi= 10.1042/BJ20030171
*cite journal | author=Lehner B, Semple JI, Brown SE, "et al." |title=Analysis of a high-throughput yeast two-hybrid system and its use to predict the function of intracellular proteins encoded within the human MHC class III region. |journal=Genomics |volume=83 |issue= 1 |pages= 153–67 |year= 2004 |pmid= 14667819 |doi=
*cite journal | author=Ota T, Suzuki Y, Nishikawa T, "et al." |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285
*cite journal | author=Brandenberger R, Wei H, Zhang S, "et al." |title=Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation. |journal=Nat. Biotechnol. |volume=22 |issue= 6 |pages= 707–16 |year= 2005 |pmid= 15146197 |doi= 10.1038/nbt971
*cite journal | author=Beausoleil SA, Jedrychowski M, Schwartz D, "et al." |title=Large-scale characterization of HeLa cell nuclear phosphoproteins. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=101 |issue= 33 |pages= 12130–5 |year= 2004 |pmid= 15302935 |doi= 10.1073/pnas.0404720101
*cite journal | author=Goehler H, Lalowski M, Stelzl U, "et al." |title=A protein interaction network links GIT1, an enhancer of huntingtin aggregation, to Huntington's disease. |journal=Mol. Cell |volume=15 |issue= 6 |pages= 853–65 |year= 2004 |pmid= 15383276 |doi= 10.1016/j.molcel.2004.09.016
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Stelzl U, Worm U, Lalowski M, "et al." |title=A human protein-protein interaction network: a resource for annotating the proteome. |journal=Cell |volume=122 |issue= 6 |pages= 957–68 |year= 2005 |pmid= 16169070 |doi= 10.1016/j.cell.2005.08.029
*cite journal | author=Lim J, Hao T, Shaw C, "et al." |title=A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration. |journal=Cell |volume=125 |issue= 4 |pages= 801–14 |year= 2006 |pmid= 16713569 |doi= 10.1016/j.cell.2006.03.032
*cite journal | author=Liu G, Clement LC, Kanwar YS, "et al." |title=ZHX proteins regulate podocyte gene expression during the development of nephrotic syndrome. |journal=J. Biol. Chem. |volume=281 |issue= 51 |pages= 39681–92 |year= 2007 |pmid= 17056598 |doi= 10.1074/jbc.M606664200
*cite journal | author=Kim SH, Park J, Choi MC, "et al." |title=Zinc-fingers and homeoboxes 1 (ZHX1) binds DNA methyltransferase (DNMT) 3B to enhance DNMT3B-mediated transcriptional repression. |journal=Biochem. Biophys. Res. Commun. |volume=355 |issue= 2 |pages= 318–23 |year= 2007 |pmid= 17303076 |doi= 10.1016/j.bbrc.2007.01.187

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