FXR2

Fragile X mental retardation, autosomal homolog 2, also known as FXR2, is a human gene.cite web | title = Entrez Gene: FXR2 fragile X mental retardation, autosomal homolog 2| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=9513| accessdate = ]

PBB_Summary
section_title =
summary_text = The protein encoded by this gene is an RNA binding protein containing two KH domains and one RCG box, which is similar to FMRP and FXR1. It associates with polyribosomes, predominantly with 60S large ribosomal subunits. This encoded protein may self-associate or interact with FMRP and FXR1. It may have a role in the development of fragile X mental retardation syndrome.cite web | title = Entrez Gene: FXR2 fragile X mental retardation, autosomal homolog 2| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=9513| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Zhang Y, O'Connor JP, Siomi MC, "et al." |title=The fragile X mental retardation syndrome protein interacts with novel homologs FXR1 and FXR2. |journal=EMBO J. |volume=14 |issue= 21 |pages= 5358–66 |year= 1996 |pmid= 7489725 |doi=
*cite journal | author=Siomi MC, Zhang Y, Siomi H, Dreyfuss G |title=Specific sequences in the fragile X syndrome protein FMR1 and the FXR proteins mediate their binding to 60S ribosomal subunits and the interactions among them. |journal=Mol. Cell. Biol. |volume=16 |issue= 7 |pages= 3825–32 |year= 1996 |pmid= 8668200 |doi=
*cite journal | author=Tamanini F, Willemsen R, van Unen L, "et al." |title=Differential expression of FMR1, FXR1 and FXR2 proteins in human brain and testis. |journal=Hum. Mol. Genet. |volume=6 |issue= 8 |pages= 1315–22 |year= 1997 |pmid= 9259278 |doi=
*cite journal | author=Joseph DR |title=The rat androgen-binding protein (ABP/SHBG) gene contains triplet repeats similar to unstable triplets: evidence that the ABP/SHBG and the fragile X-related 2 genes overlap. |journal=Steroids |volume=63 |issue= 1 |pages= 2–4 |year= 1998 |pmid= 9437788 |doi=
*cite journal | author=Tamanini F, Bontekoe C, Bakker CE, "et al." |title=Different targets for the fragile X-related proteins revealed by their distinct nuclear localizations. |journal=Hum. Mol. Genet. |volume=8 |issue= 5 |pages= 863–9 |year= 1999 |pmid= 10196376 |doi=
*cite journal | author=Bardoni B, Schenck A, Mandel JL |title=A novel RNA-binding nuclear protein that interacts with the fragile X mental retardation (FMR1) protein. |journal=Hum. Mol. Genet. |volume=8 |issue= 13 |pages= 2557–66 |year= 2000 |pmid= 10556305 |doi=
*cite journal | author=Ceman S, Brown V, Warren ST |title=Isolation of an FMRP-associated messenger ribonucleoprotein particle and identification of nucleolin and the fragile X-related proteins as components of the complex. |journal=Mol. Cell. Biol. |volume=19 |issue= 12 |pages= 7925–32 |year= 2000 |pmid= 10567518 |doi=
*cite journal | author=Cousin P, Billotte J, Chaubert P, Shaw P |title=Physical map of 17p13 and the genes adjacent to p53. |journal=Genomics |volume=63 |issue= 1 |pages= 60–8 |year= 2000 |pmid= 10662545 |doi= 10.1006/geno.1999.6062
*cite journal | author=Tamanini F, Kirkpatrick LL, Schonkeren J, "et al." |title=The fragile X-related proteins FXR1P and FXR2P contain a functional nucleolar-targeting signal equivalent to the HIV-1 regulatory proteins. |journal=Hum. Mol. Genet. |volume=9 |issue= 10 |pages= 1487–93 |year= 2000 |pmid= 10888599 |doi=
*cite journal | author=Schenck A, Bardoni B, Moro A, "et al." |title=A highly conserved protein family interacting with the fragile X mental retardation protein (FMRP) and displaying selective interactions with FMRP-related proteins FXR1P and FXR2P. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=98 |issue= 15 |pages= 8844–9 |year= 2001 |pmid= 11438699 |doi= 10.1073/pnas.151231598
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Brill LM, Salomon AR, Ficarro SB, "et al." |title=Robust phosphoproteomic profiling of tyrosine phosphorylation sites from human T cells using immobilized metal affinity chromatography and tandem mass spectrometry. |journal=Anal. Chem. |volume=76 |issue= 10 |pages= 2763–72 |year= 2004 |pmid= 15144186 |doi= 10.1021/ac035352d
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Rush J, Moritz A, Lee KA, "et al." |title=Immunoaffinity profiling of tyrosine phosphorylation in cancer cells. |journal=Nat. Biotechnol. |volume=23 |issue= 1 |pages= 94–101 |year= 2005 |pmid= 15592455 |doi= 10.1038/nbt1046
*cite journal | author=Rual JF, Venkatesan K, Hao T, "et al." |title=Towards a proteome-scale map of the human protein-protein interaction network. |journal=Nature |volume=437 |issue= 7062 |pages= 1173–8 |year= 2005 |pmid= 16189514 |doi= 10.1038/nature04209
*cite journal | author=Lim J, Hao T, Shaw C, "et al." |title=A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration. |journal=Cell |volume=125 |issue= 4 |pages= 801–14 |year= 2006 |pmid= 16713569 |doi= 10.1016/j.cell.2006.03.032
*cite journal | author=Olsen JV, Blagoev B, Gnad F, "et al." |title=Global, "in vivo", and site-specific phosphorylation dynamics in signaling networks. |journal=Cell |volume=127 |issue= 3 |pages= 635–48 |year= 2006 |pmid= 17081983 |doi= 10.1016/j.cell.2006.09.026
*cite journal | author=Ewing RM, Chu P, Elisma F, "et al." |title=Large-scale mapping of human protein-protein interactions by mass spectrometry. |journal=Mol. Syst. Biol. |volume=3 |issue= |pages= 89 |year= 2007 |pmid= 17353931 |doi= 10.1038/msb4100134

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