VTCN1

V-set domain containing T cell activation inhibitor 1, also known as VTCN1, is a human gene.cite web | title = Entrez Gene: VTCN1 V-set domain containing T cell activation inhibitor 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=79679| accessdate = ]

PBB_Summary
section_title =
summary_text = B7H4 belongs to the B7 family (see CD80; MIM 112203) of costimulatory proteins. These proteins are expressed on the surface of antigen-presenting cells and interact with ligands (e.g., CD28; MIM 186760) on T lymphocytes. [supplied by OMIM] cite web | title = Entrez Gene: VTCN1 V-set domain containing T cell activation inhibitor 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=79679| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Maruyama K, Sugano S |title=Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides. |journal=Gene |volume=138 |issue= 1-2 |pages= 171–4 |year= 1994 |pmid= 8125298 |doi=
*cite journal | author=Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, "et al." |title=Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library. |journal=Gene |volume=200 |issue= 1-2 |pages= 149–56 |year= 1997 |pmid= 9373149 |doi=
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Watanabe N, Gavrieli M, Sedy JR, "et al." |title=BTLA is a lymphocyte inhibitory receptor with similarities to CTLA-4 and PD-1. |journal=Nat. Immunol. |volume=4 |issue= 7 |pages= 670–9 |year= 2003 |pmid= 12796776 |doi= 10.1038/ni944
*cite journal | author=Sica GL, Choi IH, Zhu G, "et al." |title=B7-H4, a molecule of the B7 family, negatively regulates T cell immunity. |journal=Immunity |volume=18 |issue= 6 |pages= 849–61 |year= 2003 |pmid= 12818165 |doi=
*cite journal | author=Prasad DV, Richards S, Mai XM, Dong C |title=B7S1, a novel B7 family member that negatively regulates T cell activation. |journal=Immunity |volume=18 |issue= 6 |pages= 863–73 |year= 2003 |pmid= 12818166 |doi=
*cite journal | author=Zang X, Loke P, Kim J, "et al." |title=B7x: a widely expressed B7 family member that inhibits T cell activation. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=100 |issue= 18 |pages= 10388–92 |year= 2003 |pmid= 12920180 |doi= 10.1073/pnas.1434299100
*cite journal | author=Clark HF, Gurney AL, Abaya E, "et al." |title=The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. |journal=Genome Res. |volume=13 |issue= 10 |pages= 2265–70 |year= 2003 |pmid= 12975309 |doi= 10.1101/gr.1293003
*cite journal | author=Choi IH, Zhu G, Sica GL, "et al." |title=Genomic organization and expression analysis of B7-H4, an immune inhibitory molecule of the B7 family. |journal=J. Immunol. |volume=171 |issue= 9 |pages= 4650–4 |year= 2004 |pmid= 14568939 |doi=
*cite journal | author=Brandenberger R, Wei H, Zhang S, "et al." |title=Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation. |journal=Nat. Biotechnol. |volume=22 |issue= 6 |pages= 707–16 |year= 2005 |pmid= 15146197 |doi= 10.1038/nbt971
*cite journal | author=Salceda S, Tang T, Kmet M, "et al." |title=The immunomodulatory protein B7-H4 is overexpressed in breast and ovarian cancers and promotes epithelial cell transformation. |journal=Exp. Cell Res. |volume=306 |issue= 1 |pages= 128–41 |year= 2005 |pmid= 15878339 |doi= 10.1016/j.yexcr.2005.01.018
*cite journal | author=Kimura K, Wakamatsu A, Suzuki Y, "et al." |title=Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. |journal=Genome Res. |volume=16 |issue= 1 |pages= 55–65 |year= 2006 |pmid= 16344560 |doi= 10.1101/gr.4039406
*cite journal | author=Kryczek I, Zou L, Rodriguez P, "et al." |title=B7-H4 expression identifies a novel suppressive macrophage population in human ovarian carcinoma. |journal=J. Exp. Med. |volume=203 |issue= 4 |pages= 871–81 |year= 2006 |pmid= 16606666 |doi= 10.1084/jem.20050930
*cite journal | author=Kryczek I, Wei S, Zou L, "et al." |title=Cutting edge: induction of B7-H4 on APCs through IL-10: novel suppressive mode for regulatory T cells. |journal=J. Immunol. |volume=177 |issue= 1 |pages= 40–4 |year= 2006 |pmid= 16785496 |doi=
*cite journal | author=Krambeck AE, Thompson RH, Dong H, "et al." |title=B7-H4 expression in renal cell carcinoma and tumor vasculature: associations with cancer progression and survival. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=103 |issue= 27 |pages= 10391–6 |year= 2006 |pmid= 16798883 |doi= 10.1073/pnas.0600937103
*cite journal | author=Chen Y, Yang C, Xie Z, "et al." |title=Expression of the novel co-stimulatory molecule B7-H4 by renal tubular epithelial cells. |journal=Kidney Int. |volume=70 |issue= 12 |pages= 2092–9 |year= 2007 |pmid= 17051145 |doi= 10.1038/sj.ki.5001867
*cite journal | author=Simon I, Katsaros D, Rigault de la Longrais I, "et al." |title=B7-H4 is over-expressed in early-stage ovarian cancer and is independent of CA125 expression. |journal=Gynecol. Oncol. |volume=106 |issue= 2 |pages= 334–41 |year= 2007 |pmid= 17498784 |doi= 10.1016/j.ygyno.2007.03.035
*cite journal | author=Miyatake T, Tringler B, Liu W, "et al." |title=B7-H4 (DD-O110) is overexpressed in high risk uterine endometrioid adenocarcinomas and inversely correlated with tumor T-cell infiltration. |journal=Gynecol. Oncol. |volume=106 |issue= 1 |pages= 119–27 |year= 2007 |pmid= 17509674 |doi= 10.1016/j.ygyno.2007.03.039

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