SNRPB2

SNRPB2

Small nuclear ribonucleoprotein polypeptide B", also known as SNRPB2, is a human gene.cite web | title = Entrez Gene: SNRPB2 small nuclear ribonucleoprotein polypeptide B"| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=6629| accessdate = ]

PBB_Summary
section_title =
summary_text = The protein encoded by this gene associates with stem loop IV of U2 small nuclear ribonucleoprotein (U2 snRNP) in the presence of snRNP-A'. The encoded protein may play a role in pre-mRNA splicing. Autoantibodies from patients with systemic lupus erythematosus frequently recognize epitopes on the encoded protein. Two transcript variants encoding the same protein have been found for this gene.cite web | title = Entrez Gene: SNRPB2 small nuclear ribonucleoprotein polypeptide B"| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=6629| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Feeney RJ, Zieve GW |title=Nuclear exchange of the U1 and U2 snRNP-specific proteins. |journal=J. Cell Biol. |volume=110 |issue= 4 |pages= 871–81 |year= 1990 |pmid= 2139037 |doi=
*cite journal | author=Habets WJ, Sillekens PT, Hoet MH, "et al." |title=Analysis of a cDNA clone expressing a human autoimmune antigen: full-length sequence of the U2 small nuclear RNA-associated B" antigen. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=84 |issue= 8 |pages= 2421–5 |year= 1987 |pmid= 2951739 |doi=
*cite journal | author=Laitinen J, Saris P, Hölttä E, Pettersson I |title=U2-snRNP B" protein gene is an early growth-inducible gene. |journal=J. Cell. Biochem. |volume=58 |issue= 4 |pages= 490–8 |year= 1995 |pmid= 7593271 |doi= 10.1002/jcb.240580412
*cite journal | author=Hong W, Bennett M, Xiao Y, "et al." |title=Association of U2 snRNP with the spliceosomal complex E. |journal=Nucleic Acids Res. |volume=25 |issue= 2 |pages= 354–61 |year= 1997 |pmid= 9016565 |doi=
*cite journal | author=Liu Q, Fischer U, Wang F, Dreyfuss G |title=The spinal muscular atrophy disease gene product, SMN, and its associated protein SIP1 are in a complex with spliceosomal snRNP proteins. |journal=Cell |volume=90 |issue= 6 |pages= 1013–21 |year= 1997 |pmid= 9323129 |doi=
*cite journal | author=Moraitou M, Patrinou-Georgoula M, Guialis A |title=Structural/functional properties of a mammalian multi-component structure containing all major spliceosomal small nuclear ribonucleoprotein particles. |journal=Biochem. J. |volume=332 ( Pt 1) |issue= |pages= 135–44 |year= 1998 |pmid= 9576861 |doi=
*cite journal | author=Price SR, Evans PR, Nagai K |title=Crystal structure of the spliceosomal U2B"-U2A' protein complex bound to a fragment of U2 small nuclear RNA. |journal=Nature |volume=394 |issue= 6694 |pages= 645–50 |year= 1998 |pmid= 9716128 |doi= 10.1038/29234
*cite journal | author=Neubauer G, King A, Rappsilber J, "et al." |title=Mass spectrometry and EST-database searching allows characterization of the multi-protein spliceosome complex. |journal=Nat. Genet. |volume=20 |issue= 1 |pages= 46–50 |year= 1998 |pmid= 9731529 |doi= 10.1038/1700
*cite journal | author=Bühler D, Raker V, Lührmann R, Fischer U |title=Essential role for the tudor domain of SMN in spliceosomal U snRNP assembly: implications for spinal muscular atrophy. |journal=Hum. Mol. Genet. |volume=8 |issue= 13 |pages= 2351–7 |year= 2000 |pmid= 10556282 |doi=
*cite journal | author=Pellizzoni L, Charroux B, Rappsilber J, "et al." |title=A functional interaction between the survival motor neuron complex and RNA polymerase II. |journal=J. Cell Biol. |volume=152 |issue= 1 |pages= 75–85 |year= 2001 |pmid= 11149922 |doi=
*cite journal | author=Deloukas P, Matthews LH, Ashurst J, "et al." |title=The DNA sequence and comparative analysis of human chromosome 20. |journal=Nature |volume=414 |issue= 6866 |pages= 865–71 |year= 2002 |pmid= 11780052 |doi= 10.1038/414865a
*cite journal | author=Fong YW, Zhou Q |title=Stimulatory effect of splicing factors on transcriptional elongation. |journal=Nature |volume=414 |issue= 6866 |pages= 929–33 |year= 2002 |pmid= 11780068 |doi= 10.1038/414929a
*cite journal | author=Jurica MS, Licklider LJ, Gygi SR, "et al." |title=Purification and characterization of native spliceosomes suitable for three-dimensional structural analysis. |journal=RNA |volume=8 |issue= 4 |pages= 426–39 |year= 2002 |pmid= 11991638 |doi=
*cite journal | author=Chung S, Zhou Z, Huddleston KA, "et al." |title=Crooked neck is a component of the human spliceosome and implicated in the splicing process. |journal=Biochim. Biophys. Acta |volume=1576 |issue= 3 |pages= 287–97 |year= 2002 |pmid= 12084575 |doi=
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Rush J, Moritz A, Lee KA, "et al." |title=Immunoaffinity profiling of tyrosine phosphorylation in cancer cells. |journal=Nat. Biotechnol. |volume=23 |issue= 1 |pages= 94–101 |year= 2005 |pmid= 15592455 |doi= 10.1038/nbt1046
*cite journal | author=Ewing RM, Chu P, Elisma F, "et al." |title=Large-scale mapping of human protein-protein interactions by mass spectrometry. |journal=Mol. Syst. Biol. |volume=3 |issue= |pages= 89 |year= 2007 |pmid= 17353931 |doi= 10.1038/msb4100134

PBB_Controls
update_page = yes
require_manual_inspection = no
update_protein_box = yes
update_summary = yes
update_citations = yes


Wikimedia Foundation. 2010.

Игры ⚽ Нужна курсовая?

Share the article and excerpts

Direct link
Do a right-click on the link above
and select “Copy Link”