- RNASEN
Ribonuclease III, nuclear, also known as RNASEN, is a human
gene .cite web | title = Entrez Gene: RNASEN ribonuclease III, nuclear| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=29102| accessdate = ]PBB_Summary
section_title =
summary_text = Members of the ribonuclease III superfamily of double-stranded (ds) RNA-specific endoribonucleases participate in diverse RNA maturation and decay pathways in eukaryotic and prokaryotic cells (Fortin et al., 2002). The RNase III Drosha is the core nuclease that executes the initiation step of microRNA (miRNA) processing in the nucleus (Lee et al., 2003). [supplied by OMIM] cite web | title = Entrez Gene: RNASEN ribonuclease III, nuclear| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=29102| accessdate = ]References
Further reading
PBB_Further_reading
citations =
*cite journal | author=Filippov V, Solovyev V, Filippova M, Gill SS |title=A novel type of RNase III family proteins in eukaryotes. |journal=Gene |volume=245 |issue= 1 |pages= 213–21 |year= 2000 |pmid= 10713462 |doi=
*cite journal | author=Wu H, Xu H, Miraglia LJ, Crooke ST |title=Human RNase III is a 160-kDa protein involved in preribosomal RNA processing. |journal=J. Biol. Chem. |volume=275 |issue= 47 |pages= 36957–65 |year= 2001 |pmid= 10948199 |doi= 10.1074/jbc.M005494200
*cite journal | author=Gunther M, Laithier M, Brison O |title=A set of proteins interacting with transcription factor Sp1 identified in a two-hybrid screening. |journal=Mol. Cell. Biochem. |volume=210 |issue= 1-2 |pages= 131–42 |year= 2000 |pmid= 10976766 |doi=
*cite journal | author=Fortin KR, Nicholson RH, Nicholson AW |title=Mouse ribonuclease III. cDNA structure, expression analysis, and chromosomal location. |journal=BMC Genomics |volume=3 |issue= 1 |pages= 26 |year= 2003 |pmid= 12191433 |doi=
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Lee Y, Ahn C, Han J, "et al." |title=The nuclear RNase III Drosha initiates microRNA processing. |journal=Nature |volume=425 |issue= 6956 |pages= 415–9 |year= 2003 |pmid= 14508493 |doi= 10.1038/nature01957
*cite journal | author=Ota T, Suzuki Y, Nishikawa T, "et al." |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Gregory RI, Yan KP, Amuthan G, "et al." |title=The Microprocessor complex mediates the genesis of microRNAs. |journal=Nature |volume=432 |issue= 7014 |pages= 235–40 |year= 2004 |pmid= 15531877 |doi= 10.1038/nature03120
*cite journal | author=Zeng Y, Yi R, Cullen BR |title=Recognition and cleavage of primary microRNA precursors by the nuclear processing enzyme Drosha. |journal=EMBO J. |volume=24 |issue= 1 |pages= 138–48 |year= 2005 |pmid= 15565168 |doi= 10.1038/sj.emboj.7600491
*cite journal | author=Han J, Lee Y, Yeom KH, "et al." |title=The Drosha-DGCR8 complex in primary microRNA processing. |journal=Genes Dev. |volume=18 |issue= 24 |pages= 3016–27 |year= 2005 |pmid= 15574589 |doi= 10.1101/gad.1262504
*cite journal | author=Landthaler M, Yalcin A, Tuschl T |title=The human DiGeorge syndrome critical region gene 8 and Its D. melanogaster homolog are required for miRNA biogenesis. |journal=Curr. Biol. |volume=14 |issue= 23 |pages= 2162–7 |year= 2005 |pmid= 15589161 |doi= 10.1016/j.cub.2004.11.001
*cite journal | author=Zeng Y, Cullen BR |title=Efficient processing of primary microRNA hairpins by Drosha requires flanking nonstructured RNA sequences. |journal=J. Biol. Chem. |volume=280 |issue= 30 |pages= 27595–603 |year= 2005 |pmid= 15932881 |doi= 10.1074/jbc.M504714200
*cite journal | author=Irvin-Wilson CV, Chaudhuri G |title=Alternative initiation and splicing in dicer gene expression in human breast cells. |journal=Breast Cancer Res. |volume=7 |issue= 4 |pages= R563–9 |year= 2006 |pmid= 15987463 |doi= 10.1186/bcr1043
*cite journal | author=Kimura K, Wakamatsu A, Suzuki Y, "et al." |title=Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. |journal=Genome Res. |volume=16 |issue= 1 |pages= 55–65 |year= 2006 |pmid= 16344560 |doi= 10.1101/gr.4039406
*cite journal | author=Olsen JV, Blagoev B, Gnad F, "et al." |title=Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. |journal=Cell |volume=127 |issue= 3 |pages= 635–48 |year= 2006 |pmid= 17081983 |doi= 10.1016/j.cell.2006.09.026
*cite journal | author=Sugito N, Ishiguro H, Kuwabara Y, "et al." |title=RNASEN regulates cell proliferation and affects survival in esophageal cancer patients. |journal=Clin. Cancer Res. |volume=12 |issue= 24 |pages= 7322–8 |year= 2007 |pmid= 17121874 |doi= 10.1158/1078-0432.CCR-06-0515
*cite journal | author=Kim YK, Kim VN |title=Processing of intronic microRNAs. |journal=EMBO J. |volume=26 |issue= 3 |pages= 775–83 |year= 2007 |pmid= 17255951 |doi= 10.1038/sj.emboj.7601512
*cite journal | author=Xing L, Kieff E |title=Epstein-Barr virus BHRF1 micro- and stable RNAs during latency III and after induction of replication. |journal=J. Virol. |volume=81 |issue= 18 |pages= 9967–75 |year= 2007 |pmid= 17626073 |doi= 10.1128/JVI.02244-06PBB_Controls
update_page = yes
require_manual_inspection = no
update_protein_box = yes
update_summary = yes
update_citations = yes
Wikimedia Foundation. 2010.
