PIP5K1C

Phosphatidylinositol-4-phosphate 5-kinase, type I, gamma, also known as PIP5K1C, is a human gene.cite web | title = Entrez Gene: PIP5K1C phosphatidylinositol-4-phosphate 5-kinase, type I, gamma| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=23396| accessdate = ]

PBB_Summary
section_title =
summary_text = This gene encodes a member of the type I phosphatidylinositol-4-phosphate 5-kinase family of enzymes. A similar protein in mice is found in synapses and focal adhesion plaques, and binds the FERM domain of talin through its C-terminus.cite web | title = Entrez Gene: PIP5K1C phosphatidylinositol-4-phosphate 5-kinase, type I, gamma| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=23396| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Niiro H, Clark EA |title=Branches of the B cell antigen receptor pathway are directed by protein conduits Bam32 and Carma1. |journal=Immunity |volume=19 |issue= 5 |pages= 637–40 |year= 2003 |pmid= 14614850 |doi=
*cite journal | author=Carpenter CL |title=Btk-dependent regulation of phosphoinositide synthesis. |journal=Biochem. Soc. Trans. |volume=32 |issue= Pt 2 |pages= 326–9 |year= 2004 |pmid= 15046600 |doi= 10.1042/
*cite journal | author=Ishihara H, Shibasaki Y, Kizuki N, "et al." |title=Type I phosphatidylinositol-4-phosphate 5-kinases. Cloning of the third isoform and deletion/substitution analysis of members of this novel lipid kinase family. |journal=J. Biol. Chem. |volume=273 |issue= 15 |pages= 8741–8 |year= 1998 |pmid= 9535851 |doi=
*cite journal | author=Nagase T, Ishikawa K, Miyajima N, "et al." |title=Prediction of the coding sequences of unidentified human genes. IX. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro. |journal=DNA Res. |volume=5 |issue= 1 |pages= 31–9 |year= 1998 |pmid= 9628581 |doi=
*cite journal | author=Gotthardt M, Trommsdorff M, Nevitt MF, "et al." |title=Interactions of the low density lipoprotein receptor gene family with cytosolic adaptor and scaffold proteins suggest diverse biological functions in cellular communication and signal transduction. |journal=J. Biol. Chem. |volume=275 |issue= 33 |pages= 25616–24 |year= 2000 |pmid= 10827173 |doi= 10.1074/jbc.M000955200
*cite journal | author=Wenk MR, Pellegrini L, Klenchin VA, "et al." |title=PIP kinase Igamma is the major PI(4,5)P(2) synthesizing enzyme at the synapse. |journal=Neuron |volume=32 |issue= 1 |pages= 79–88 |year= 2001 |pmid= 11604140 |doi=
*cite journal | author=Di Paolo G, Pellegrini L, Letinic K, "et al." |title=Recruitment and regulation of phosphatidylinositol phosphate kinase type 1 gamma by the FERM domain of talin. |journal=Nature |volume=420 |issue= 6911 |pages= 85–9 |year= 2002 |pmid= 12422219 |doi= 10.1038/nature01147
*cite journal | author=Ling K, Doughman RL, Firestone AJ, "et al." |title=Type I gamma phosphatidylinositol phosphate kinase targets and regulates focal adhesions. |journal=Nature |volume=420 |issue= 6911 |pages= 89–93 |year= 2002 |pmid= 12422220 |doi= 10.1038/nature01082
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Doughman RL, Firestone AJ, Wojtasiak ML, "et al." |title=Membrane ruffling requires coordination between type Ialpha phosphatidylinositol phosphate kinase and Rac signaling. |journal=J. Biol. Chem. |volume=278 |issue= 25 |pages= 23036–45 |year= 2003 |pmid= 12682053 |doi= 10.1074/jbc.M211397200
*cite journal | author=Krauss M, Kinuta M, Wenk MR, "et al." |title=ARF6 stimulates clathrin/AP-2 recruitment to synaptic membranes by activating phosphatidylinositol phosphate kinase type Igamma. |journal=J. Cell Biol. |volume=162 |issue= 1 |pages= 113–24 |year= 2003 |pmid= 12847086 |doi= 10.1083/jcb.200301006
*cite journal | author=Chang JD, Field SJ, Rameh LE, "et al." |title=Identification and characterization of a phosphoinositide phosphate kinase homolog. |journal=J. Biol. Chem. |volume=279 |issue= 12 |pages= 11672–9 |year= 2004 |pmid= 14701839 |doi= 10.1074/jbc.M309721200
*cite journal | author=Grimwood J, Gordon LA, Olsen A, "et al." |title=The DNA sequence and biology of human chromosome 19. |journal=Nature |volume=428 |issue= 6982 |pages= 529–35 |year= 2004 |pmid= 15057824 |doi= 10.1038/nature02399
*cite journal | author=Wang YJ, Li WH, Wang J, "et al." |title=Critical role of PIP5KI{gamma}87 in InsP3-mediated Ca(2+) signaling. |journal=J. Cell Biol. |volume=167 |issue= 6 |pages= 1005-10 |year= 2005 |pmid= 15611330 |doi= 10.1083/jcb.200408008
*cite journal | author=Bairstow SF, Ling K, Su X, "et al." |title=Type Igamma661 phosphatidylinositol phosphate kinase directly interacts with AP2 and regulates endocytosis. |journal=J. Biol. Chem. |volume=281 |issue= 29 |pages= 20632–42 |year= 2006 |pmid= 16707488 |doi= 10.1074/jbc.M601465200
*cite journal | author=Krauss M, Kukhtina V, Pechstein A, Haucke V |title=Stimulation of phosphatidylinositol kinase type I-mediated phosphatidylinositol (4,5)-bisphosphate synthesis by AP-2mu-cargo complexes. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=103 |issue= 32 |pages= 11934–9 |year= 2006 |pmid= 16880396 |doi= 10.1073/pnas.0510306103
*cite journal | author=Auvinen E, Kivi N, Vaheri A |title=Regulation of ezrin localization by Rac1 and PIPK in human epithelial cells. |journal=Exp. Cell Res. |volume=313 |issue= 4 |pages= 824–33 |year= 2007 |pmid= 17229424 |doi= 10.1016/j.yexcr.2006.12.002
*cite journal | author=Ling K, Bairstow SF, Carbonara C, "et al." |title=Type Igamma phosphatidylinositol phosphate kinase modulates adherens junction and E-cadherin trafficking via a direct interaction with mu 1B adaptin. |journal=J. Cell Biol. |volume=176 |issue= 3 |pages= 343–53 |year= 2007 |pmid= 17261850 |doi= 10.1083/jcb.200606023

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