SIVA1

SIVA1, apoptosis-inducing factor, also known as SIVA1, is a human gene.cite web | title = Entrez Gene: SIVA1 SIVA1, apoptosis-inducing factor| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=10572| accessdate = ]

PBB_Summary
section_title =
summary_text = This gene encodes a protein with an important role in the apoptotic (programmed cell death) pathway induced by the CD27 antigen, a member of the tumor necrosis factor receptor (TFNR) superfamily. The CD27 antigen cytoplasmic tail binds to the N-terminus of this protein. Two alternatively spliced transcript variants encoding distinct proteins have been described.cite web | title = Entrez Gene: SIVA1 SIVA1, apoptosis-inducing factor| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=10572| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Maruyama K, Sugano S |title=Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides. |journal=Gene |volume=138 |issue= 1-2 |pages= 171–4 |year= 1994 |pmid= 8125298 |doi=
*cite journal | author=Prasad KV, Ao Z, Yoon Y, "et al." |title=CD27, a member of the tumor necrosis factor receptor family, induces apoptosis and binds to Siva, a proapoptotic protein. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=94 |issue= 12 |pages= 6346–51 |year= 1997 |pmid= 9177220 |doi=
*cite journal | author=Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, "et al." |title=Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library. |journal=Gene |volume=200 |issue= 1-2 |pages= 149–56 |year= 1997 |pmid= 9373149 |doi=
*cite journal | author=Henke A, Launhardt H, Klement K, "et al." |title=Apoptosis in coxsackievirus B3-caused diseases: interaction between the capsid protein VP2 and the proapoptotic protein siva. |journal=J. Virol. |volume=74 |issue= 9 |pages= 4284–90 |year= 2000 |pmid= 10756043 |doi=
*cite journal | author=Cao C, Ren X, Kharbanda S, "et al." |title=The ARG tyrosine kinase interacts with Siva-1 in the apoptotic response to oxidative stress. |journal=J. Biol. Chem. |volume=276 |issue= 15 |pages= 11465–8 |year= 2001 |pmid= 11278261 |doi= 10.1074/jbc.C100050200
*cite journal | author=Henke A, Nestler M, Strunze S, "et al." |title=The apoptotic capability of coxsackievirus B3 is influenced by the efficient interaction between the capsid protein VP2 and the proapoptotic host protein Siva. |journal=Virology |volume=289 |issue= 1 |pages= 15–22 |year= 2001 |pmid= 11601913 |doi= 10.1006/viro.2001.1082
*cite journal | author=Held-Feindt J, Mentlein R |title=CD70/CD27 ligand, a member of the TNF family, is expressed in human brain tumors. |journal=Int. J. Cancer |volume=98 |issue= 3 |pages= 352–6 |year= 2002 |pmid= 11920585 |doi=
*cite journal | author=Xue L, Chu F, Cheng Y, "et al." |title=Siva-1 binds to and inhibits BCL-X(L)-mediated protection against UV radiation-induced apoptosis. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 10 |pages= 6925–30 |year= 2002 |pmid= 12011449 |doi= 10.1073/pnas.102182299
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Spinicelli S, Nocentini G, Ronchetti S, "et al." |title=GITR interacts with the pro-apoptotic protein Siva and induces apoptosis. |journal=Cell Death Differ. |volume=9 |issue= 12 |pages= 1382–4 |year= 2003 |pmid= 12478477 |doi= 10.1038/sj.cdd.4401140
*cite journal | author=Chu F, Borthakur A, Sun X, "et al." |title=The Siva-1 putative amphipathic helical region (SAH) is sufficient to bind to BCL-XL and sensitize cells to UV radiation induced apoptosis. |journal=Apoptosis |volume=9 |issue= 1 |pages= 83–95 |year= 2004 |pmid= 14739602 |doi= 10.1023/B:APPT.0000012125.01799.4c
*cite journal | author=Py B, Slomianny C, Auberger P, "et al." |title=Siva-1 and an alternative splice form lacking the death domain, Siva-2, similarly induce apoptosis in T lymphocytes via a caspase-dependent mitochondrial pathway. |journal=J. Immunol. |volume=172 |issue= 7 |pages= 4008–17 |year= 2004 |pmid= 15034012 |doi=
*cite journal | author=Fortin A, MacLaurin JG, Arbour N, "et al." |title=The proapoptotic gene SIVA is a direct transcriptional target for the tumor suppressors p53 and E2F1. |journal=J. Biol. Chem. |volume=279 |issue= 27 |pages= 28706–14 |year= 2004 |pmid= 15105421 |doi= 10.1074/jbc.M400376200
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Chu F, Barkinge J, Hawkins S, "et al." |title=Expression of Siva-1 protein or its putative amphipathic helical region enhances cisplatin-induced apoptosis in breast cancer cells: effect of elevated levels of BCL-2. |journal=Cancer Res. |volume=65 |issue= 12 |pages= 5301–9 |year= 2005 |pmid= 15958577 |doi= 10.1158/0008-5472.CAN-04-3270
*cite journal | author=Gudi R, Barkinge J, Hawkins S, "et al." |title=Siva-1 negatively regulates NF-kappaB activity: effect on T-cell receptor-mediated activation-induced cell death (AICD). |journal=Oncogene |volume=25 |issue= 24 |pages= 3458–62 |year= 2006 |pmid= 16491128 |doi= 10.1038/sj.onc.1209381
*cite journal | author=Nestler M, Martin U, Hortschansky P, "et al." |title=The zinc containing pro-apoptotic protein siva interacts with the peroxisomal membrane protein pmp22. |journal=Mol. Cell. Biochem. |volume=287 |issue= 1-2 |pages= 147–55 |year= 2006 |pmid= 16683188 |doi= 10.1007/s11010-005-9082-6
*cite journal | author=Severino A, Abbruzzese C, Manente L, "et al." |title=Human papillomavirus-16 E7 interacts with Siva-1 and modulates apoptosis in HaCaT human immortalized keratinocytes. |journal=J. Cell. Physiol. |volume=212 |issue= 1 |pages= 118–25 |year= 2007 |pmid= 17348035 |doi= 10.1002/jcp.21011

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