ITGB1BP1

Integrin beta 1 binding protein 1, also known as ITGB1BP1, is a human gene.cite web | title = Entrez Gene: ITGB1BP1 integrin beta 1 binding protein 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=9270| accessdate = ]

PBB_Summary
section_title =
summary_text = The cytoplasmic domains of integrins are essential for cell adhesion. The protein encoded by this gene binds to the beta1 integrin cytoplasmic domain. The interaction between this protein and beta1 integrin is highly specific. Two isoforms of this protein are derived from alternatively spliced transcripts. The shorter form of this protein does not interact with the beta1 integrin cytoplasmic domain. The longer form is a phosphoprotein and the extent of its phosphorylation is regulated by the cell-matrix interaction, suggesting an important role of this protein during integrin-dependent cell adhesion.cite web | title = Entrez Gene: ITGB1BP1 integrin beta 1 binding protein 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=9270| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Andersson B, Wentland MA, Ricafrente JY, "et al." |title=A "double adaptor" method for improved shotgun library construction. |journal=Anal. Biochem. |volume=236 |issue= 1 |pages= 107–13 |year= 1996 |pmid= 8619474 |doi= 10.1006/abio.1996.0138
*cite journal | author=Yu W, Andersson B, Worley KC, "et al." |title=Large-scale concatenation cDNA sequencing. |journal=Genome Res. |volume=7 |issue= 4 |pages= 353–8 |year= 1997 |pmid= 9110174 |doi=
*cite journal | author=Chang DD, Wong C, Smith H, Liu J |title=ICAP-1, a novel beta1 integrin cytoplasmic domain-associated protein, binds to a conserved and functionally important NPXY sequence motif of beta1 integrin. |journal=J. Cell Biol. |volume=138 |issue= 5 |pages= 1149–57 |year= 1997 |pmid= 9281591 |doi=
*cite journal | author=Bouvard D, Block MR |title=Calcium/calmodulin-dependent protein kinase II controls integrin alpha5beta1-mediated cell adhesion through the integrin cytoplasmic domain associated protein-1alpha. |journal=Biochem. Biophys. Res. Commun. |volume=252 |issue= 1 |pages= 46–50 |year= 1998 |pmid= 9813144 |doi= 10.1006/bbrc.1998.9592
*cite journal | author=Gotthardt M, Trommsdorff M, Nevitt MF, "et al." |title=Interactions of the low density lipoprotein receptor gene family with cytosolic adaptor and scaffold proteins suggest diverse biological functions in cellular communication and signal transduction. |journal=J. Biol. Chem. |volume=275 |issue= 33 |pages= 25616–24 |year= 2000 |pmid= 10827173 |doi= 10.1074/jbc.M000955200
*cite journal | author=Zhang J, Clatterbuck RE, Rigamonti D, "et al." |title=Interaction between krit1 and icap1alpha infers perturbation of integrin beta1-mediated angiogenesis in the pathogenesis of cerebral cavernous malformation. |journal=Hum. Mol. Genet. |volume=10 |issue= 25 |pages= 2953–60 |year= 2002 |pmid= 11741838 |doi=
*cite journal | author=Chang DD, Hoang BQ, Liu J, Springer TA |title=Molecular basis for interaction between Icap1 alpha PTB domain and beta 1 integrin. |journal=J. Biol. Chem. |volume=277 |issue= 10 |pages= 8140–5 |year= 2002 |pmid= 11741908 |doi= 10.1074/jbc.M109031200
*cite journal | author=Zawistowski JS, Serebriiskii IG, Lee MF, "et al." |title=KRIT1 association with the integrin-binding protein ICAP-1: a new direction in the elucidation of cerebral cavernous malformations (CCM1) pathogenesis. |journal=Hum. Mol. Genet. |volume=11 |issue= 4 |pages= 389–96 |year= 2002 |pmid= 11854171 |doi=
*cite journal | author=Fournier HN, Dupé-Manet S, Bouvard D, "et al." |title=Integrin cytoplasmic domain-associated protein 1alpha (ICAP-1alpha ) interacts directly with the metastasis suppressor nm23-H2, and both proteins are targeted to newly formed cell adhesion sites upon integrin engagement. |journal=J. Biol. Chem. |volume=277 |issue= 23 |pages= 20895–902 |year= 2002 |pmid= 11919189 |doi= 10.1074/jbc.M200200200
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Ota T, Suzuki Y, Nishikawa T, "et al." |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285
*cite journal | author=Hillman RT, Green RE, Brenner SE |title=An unappreciated role for RNA surveillance. |journal=Genome Biol. |volume=5 |issue= 2 |pages= R8 |year= 2005 |pmid= 14759258 |doi= 10.1186/gb-2004-5-2-r8
*cite journal | author=Xia H, Nho RS, Kahm J, "et al." |title=Focal adhesion kinase is upstream of phosphatidylinositol 3-kinase/Akt in regulating fibroblast survival in response to contraction of type I collagen matrices via a beta 1 integrin viability signaling pathway. |journal=J. Biol. Chem. |volume=279 |issue= 31 |pages= 33024–34 |year= 2004 |pmid= 15166238 |doi= 10.1074/jbc.M313265200
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Fournier HN, Dupé-Manet S, Bouvard D, "et al." |title=Nuclear translocation of integrin cytoplasmic domain-associated protein 1 stimulates cellular proliferation. |journal=Mol. Biol. Cell |volume=16 |issue= 4 |pages= 1859–71 |year= 2005 |pmid= 15703214 |doi= 10.1091/mbc.E04-08-0744
*cite journal | author=Rual JF, Venkatesan K, Hao T, "et al." |title=Towards a proteome-scale map of the human protein-protein interaction network. |journal=Nature |volume=437 |issue= 7062 |pages= 1173–8 |year= 2005 |pmid= 16189514 |doi= 10.1038/nature04209
*cite journal | author=Oh JH, Yang JO, Hahn Y, "et al." |title=Transcriptome analysis of human gastric cancer. |journal=Mamm. Genome |volume=16 |issue= 12 |pages= 942–54 |year= 2006 |pmid= 16341674 |doi= 10.1007/s00335-005-0075-2
*cite journal | author=Kimura K, Wakamatsu A, Suzuki Y, "et al." |title=Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. |journal=Genome Res. |volume=16 |issue= 1 |pages= 55–65 |year= 2006 |pmid= 16344560 |doi= 10.1101/gr.4039406
*cite journal | author=Stroeken PJ, Alvarez B, Van Rheenen J, "et al." |title=Integrin cytoplasmic domain-associated protein-1 (ICAP-1) interacts with the ROCK-I kinase at the plasma membrane. |journal=J. Cell. Physiol. |volume=208 |issue= 3 |pages= 620–8 |year= 2006 |pmid= 16741948 |doi= 10.1002/jcp.20699
*cite journal | author=Furusu A, Nakayama K, Xu Q, "et al." |title=MAP kinase-dependent, NF-kappaB-independent regulation of inhibitor of apoptosis protein genes by TNF-alpha. |journal=J. Cell. Physiol. |volume=210 |issue= 3 |pages= 703–10 |year= 2007 |pmid= 17133355 |doi= 10.1002/jcp.20881

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