STX2

STX2

Syntaxin 2, also known as STX2, is a human gene.cite web | title = Entrez Gene: STX2 syntaxin 2| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=2054| accessdate = ]

PBB_Summary
section_title =
summary_text = The product of this gene belongs to the syntaxin/epimorphin family of proteins. The syntaxins are a large protein family implicated in the targeting and fusion of intracellular transport vesicles. The product of this gene regulates epithelial-mesenchymal interactions and epithelial cell morphogenesis and activation. Alternatively spliced transcript variants encoding different isoforms have been identified.cite web | title = Entrez Gene: STX2 syntaxin 2| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=2054| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Hirai Y, Takebe K, Takashina M, "et al." |title=Epimorphin: a mesenchymal protein essential for epithelial morphogenesis. |journal=Cell |volume=69 |issue= 3 |pages= 471–81 |year= 1992 |pmid= 1581962 |doi=
*cite journal | author=Hata Y, Südhof TC |title=A novel ubiquitous form of Munc-18 interacts with multiple syntaxins. Use of the yeast two-hybrid system to study interactions between proteins involved in membrane traffic. |journal=J. Biol. Chem. |volume=270 |issue= 22 |pages= 13022–8 |year= 1995 |pmid= 7768895 |doi=
*cite journal | author=Li C, Ullrich B, Zhang JZ, "et al." |title=Ca(2+)-dependent and -independent activities of neural and non-neural synaptotagmins. |journal=Nature |volume=375 |issue= 6532 |pages= 594–9 |year= 1995 |pmid= 7791877 |doi= 10.1038/375594a0
*cite journal | author=Hirai Y |title=Molecular cloning of human epimorphin: identification of isoforms and their unique properties. |journal=Biochem. Biophys. Res. Commun. |volume=191 |issue= 3 |pages= 1332–7 |year= 1993 |pmid= 8466509 |doi= 10.1006/bbrc.1993.1363
*cite journal | author=Oka Y, Hirai Y |title=Inductive influences of epimorphin on endothelial cells in vitro. |journal=Exp. Cell Res. |volume=222 |issue= 1 |pages= 189–98 |year= 1996 |pmid= 8549663 |doi= 10.1006/excr.1996.0024
*cite journal | author=Andersson B, Wentland MA, Ricafrente JY, "et al." |title=A "double adaptor" method for improved shotgun library construction. |journal=Anal. Biochem. |volume=236 |issue= 1 |pages= 107–13 |year= 1996 |pmid= 8619474 |doi= 10.1006/abio.1996.0138
*cite journal | author=Zha H, Remmers EF, Szpirer C, "et al." |title=The epimorphin gene is highly conserved among humans, mice, and rats and maps to human chromosome 7, mouse chromosome 5, and rat chromosome 12. |journal=Genomics |volume=37 |issue= 3 |pages= 386–9 |year= 1997 |pmid= 8938452 |doi= 10.1006/geno.1996.0574
*cite journal | author=Betz A, Okamoto M, Benseler F, Brose N |title=Direct interaction of the rat unc-13 homologue Munc13-1 with the N terminus of syntaxin. |journal=J. Biol. Chem. |volume=272 |issue= 4 |pages= 2520–6 |year= 1997 |pmid= 8999968 |doi=
*cite journal | author=Tellam JT, Macaulay SL, McIntosh S, "et al." |title=Characterization of Munc-18c and syntaxin-4 in 3T3-L1 adipocytes. Putative role in insulin-dependent movement of GLUT-4. |journal=J. Biol. Chem. |volume=272 |issue= 10 |pages= 6179–86 |year= 1997 |pmid= 9045631 |doi=
*cite journal | author=Yu W, Andersson B, Worley KC, "et al." |title=Large-scale concatenation cDNA sequencing. |journal=Genome Res. |volume=7 |issue= 4 |pages= 353–8 |year= 1997 |pmid= 9110174 |doi=
*cite journal | author=Koshida S, Hirai Y |title=Identification of cellular recognition sequence of epimorphin and critical role of cell/epimorphin interaction in lung branching morphogenesis. |journal=Biochem. Biophys. Res. Commun. |volume=234 |issue= 2 |pages= 522–5 |year= 1997 |pmid= 9177305 |doi= 10.1006/bbrc.1997.6673
*cite journal | author=Hirai Y, Lochter A, Galosy S, "et al." |title=Epimorphin functions as a key morphoregulator for mammary epithelial cells. |journal=J. Cell Biol. |volume=140 |issue= 1 |pages= 159–69 |year= 1998 |pmid= 9425164 |doi=
*cite journal | author=Thomas DM, Ferguson GD, Herschman HR, Elferink LA |title=Functional and biochemical analysis of the C2 domains of synaptotagmin IV. |journal=Mol. Biol. Cell |volume=10 |issue= 7 |pages= 2285–95 |year= 1999 |pmid= 10397765 |doi=
*cite journal | author=Pabst S, Hazzard JW, Antonin W, "et al." |title=Selective interaction of complexin with the neuronal SNARE complex. Determination of the binding regions. |journal=J. Biol. Chem. |volume=275 |issue= 26 |pages= 19808–18 |year= 2000 |pmid= 10777504 |doi= 10.1074/jbc.M002571200
*cite journal | author=Kauppi M, Wohlfahrt G, Olkkonen VM |title=Analysis of the Munc18b-syntaxin binding interface. Use of a mutant Munc18b to dissect the functions of syntaxins 2 and 3. |journal=J. Biol. Chem. |volume=277 |issue= 46 |pages= 43973–9 |year= 2003 |pmid= 12198139 |doi= 10.1074/jbc.M208315200
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Terasaki Y, Fukuda Y, Suga M, "et al." |title=Epimorphin expression in interstitial pneumonia. |journal=Respir. Res. |volume=6 |issue= |pages= 6 |year= 2006 |pmid= 15651999 |doi= 10.1186/1465-9921-6-6
*cite journal | author=Band AM, Kuismanen E |title=Localization of plasma membrane t-SNAREs syntaxin 2 and 3 in intracellular compartments. |journal=BMC Cell Biol. |volume=6 |issue= 1 |pages= 26 |year= 2006 |pmid= 15943887 |doi= 10.1186/1471-2121-6-26
*cite journal | author=Low SH, Vasanji A, Nanduri J, "et al." |title=Syntaxins 3 and 4 are concentrated in separate clusters on the plasma membrane before the establishment of cell polarity. |journal=Mol. Biol. Cell |volume=17 |issue= 2 |pages= 977–89 |year= 2006 |pmid= 16339081 |doi= 10.1091/mbc.E05-05-0462

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