PSPH

PSPH

Phosphoserine phosphatase, also known as PSPH, is a human gene.cite web | title = Entrez Gene: PSPH phosphoserine phosphatase| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=5723| accessdate = ]

PBB_Summary
section_title =
summary_text = The protein encoded by this gene belongs to a subfamily of the phosphotransferases. This encoded enzyme is responsible for the third and last step in L-serine formation. It catalyzes magnesium-dependent hydrolysis of L-phosphoserine and is also involved in an exchange reaction between L-serine and L-phosphoserine. Deficiency of this protein is thought to be linked to Williams syndrome.cite web | title = Entrez Gene: PSPH phosphoserine phosphatase| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=5723| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Minelli A, Piantanida M, Maserati E, "et al." |title=Gene dosage effect in acquired monosomy 7: distinct behaviour of beta-glucuronidase and phosphoserine phosphatase. |journal=Genes Chromosomes Cancer |volume=1 |issue= 3 |pages= 216–20 |year= 1991 |pmid= 1964582 |doi=
*cite journal | author=Veeranna , Shetty KT |title=Phosphoserine phosphatase of human brain: partial purification, characterization, regional distribution, and effect of certain modulators including psychoactive drugs. |journal=Neurochem. Res. |volume=15 |issue= 12 |pages= 1203–10 |year= 1991 |pmid= 1965857 |doi=
*cite journal | author=Novelli G, Dallapiccola B |title=Gene dosage studies regionally assign the phosphoserine phosphatase gene to 7p15.1 or 2. |journal=Ann. Genet. |volume=31 |issue= 3 |pages= 195–6 |year= 1989 |pmid= 2851960 |doi=
*cite journal | author=Moro-Furlani AM, Turner VS, Hopkinson DA |title=Genetical and biochemical studies on human phosphoserine phosphatase. |journal=Ann. Hum. Genet. |volume=43 |issue= 4 |pages= 323–33 |year= 1980 |pmid= 6249179 |doi=
*cite journal | author=Koch GA, Eddy RL, Haley LL, "et al." |title=Assignment of the human phosphoserine phosphatase gene (PSP) to the pter leads to q22 region of chromosome 7. |journal=Cytogenet. Cell Genet. |volume=35 |issue= 1 |pages= 67–9 |year= 1983 |pmid= 6297854 |doi=
*cite journal | author=Sparkes RS, Mohandas T, Sparkes MC |title=The human phosphoserine phosphatase gene (PSP) is mapped to chromosome 7 by somatic cell genetic analysis. |journal=Cytogenet. Cell Genet. |volume=35 |issue= 1 |pages= 70–1 |year= 1983 |pmid= 6297855 |doi=
*cite journal | author=Maruyama K, Sugano S |title=Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides. |journal=Gene |volume=138 |issue= 1-2 |pages= 171–4 |year= 1994 |pmid= 8125298 |doi=
*cite journal | author=Collet JF, Gerin I, Rider MH, "et al." |title=Human L-3-phosphoserine phosphatase: sequence, expression and evidence for a phosphoenzyme intermediate. |journal=FEBS Lett. |volume=408 |issue= 3 |pages= 281–4 |year= 1997 |pmid= 9188776 |doi=
*cite journal | author=Jaeken J, Detheux M, Fryns JP, "et al." |title=Phosphoserine phosphatase deficiency in a patient with Williams syndrome. |journal=J. Med. Genet. |volume=34 |issue= 7 |pages= 594–6 |year= 1997 |pmid= 9222972 |doi=
*cite journal | author=Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, "et al." |title=Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library. |journal=Gene |volume=200 |issue= 1-2 |pages= 149–56 |year= 1997 |pmid= 9373149 |doi=
*cite journal | author=Collet JF, Stroobant V, Pirard M, "et al." |title=A new class of phosphotransferases phosphorylated on an aspartate residue in an amino-terminal DXDX(T/V) motif. |journal=J. Biol. Chem. |volume=273 |issue= 23 |pages= 14107–12 |year= 1998 |pmid= 9603909 |doi=
*cite journal | author=Collet JF, Stroobant V, Van Schaftingen E |title=Mechanistic studies of phosphoserine phosphatase, an enzyme related to P-type ATPases. |journal=J. Biol. Chem. |volume=274 |issue= 48 |pages= 33985–90 |year= 1999 |pmid= 10567362 |doi=
*cite journal | author=Peeraer Y, Rabijns A, Verboven C, "et al." |title=Purification, crystallization and preliminary X-ray diffraction analysis of human phosphoserine phosphatase. |journal=Acta Crystallogr. D Biol. Crystallogr. |volume=58 |issue= Pt 1 |pages= 133–4 |year= 2002 |pmid= 11752790 |doi=
*cite journal | author=Kim HY, Heo YS, Kim JH, "et al." |title=Molecular basis for the local conformational rearrangement of human phosphoserine phosphatase. |journal=J. Biol. Chem. |volume=277 |issue= 48 |pages= 46651–8 |year= 2003 |pmid= 12213811 |doi= 10.1074/jbc.M204866200
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Veiga-da-Cunha M, Collet JF, Prieur B, "et al." |title=Mutations responsible for 3-phosphoserine phosphatase deficiency. |journal=Eur. J. Hum. Genet. |volume=12 |issue= 2 |pages= 163–6 |year= 2004 |pmid= 14673469 |doi= 10.1038/sj.ejhg.5201083
*cite journal | author=Ota T, Suzuki Y, Nishikawa T, "et al." |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285
*cite journal | author=Peeraer Y, Rabijns A, Collet JF, "et al." |title=How calcium inhibits the magnesium-dependent enzyme human phosphoserine phosphatase. |journal=Eur. J. Biochem. |volume=271 |issue= 16 |pages= 3421–7 |year= 2004 |pmid= 15291819 |doi= 10.1111/j.0014-2956.2004.04277.x
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Ewing RM, Chu P, Elisma F, "et al." |title=Large-scale mapping of human protein-protein interactions by mass spectrometry. |journal=Mol. Syst. Biol. |volume=3 |issue= |pages= 89 |year= 2007 |pmid= 17353931 |doi= 10.1038/msb4100134

PBB_Controls
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