- PDCL
Phosducin-like, also known as PDCL, is a human
gene .cite web | title = Entrez Gene: PDCL phosducin-like| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=5082| accessdate = ]PBB_Summary
section_title =
summary_text = Phosducin-like protein is a putative modulator of heterotrimeric G proteins. The protein shares extensive amino acid sequence homology with phosducin, a phosphoprotein expressed in retina and pineal gland. Both phosducin-like protein and phosphoducin have been shown to regulate G-protein signaling by binding to the beta-gamma subunits of G proteins.cite web | title = Entrez Gene: PDCL phosducin-like| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=5082| accessdate = ]References
Further reading
PBB_Further_reading
citations =
*cite journal | author=Miles MF, Barhite S, Sganga M, Elliott M |title=Phosducin-like protein: an ethanol-responsive potential modulator of guanine nucleotide-binding protein function. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=90 |issue= 22 |pages= 10831–5 |year= 1993 |pmid= 8248177 |doi=
*cite journal | author=Thibault C, Feng Wang J, Charnas R, "et al." |title=Cloning and characterization of the rat and human phosducin-like protein genes: structure, expression and chromosomal localization. |journal=Biochim. Biophys. Acta |volume=1444 |issue= 3 |pages= 346–54 |year= 1999 |pmid= 10095058 |doi=
*cite journal | author=Lazarov ME, Martin MM, Willardson BM, Elton TS |title=Human phosducin-like protein (hPhLP) messenger RNA stability is regulated by cis-acting instability elements present in the 3'-untranslated region. |journal=Biochim. Biophys. Acta |volume=1446 |issue= 3 |pages= 253–64 |year= 1999 |pmid= 10524200 |doi=
*cite journal | author=Ruiz-Gómez A, Humrich J, Murga C, "et al." |title=Phosphorylation of phosducin and phosducin-like protein by G protein-coupled receptor kinase 2. |journal=J. Biol. Chem. |volume=275 |issue= 38 |pages= 29724–30 |year= 2000 |pmid= 10884381 |doi= 10.1074/jbc.M001864200
*cite journal | author=Lazarov ME, Martin MM, Willardson BM, Elton TS |title=Molecular cloning and characterization of the human phosducin-like protein (hPhLP) promoter. |journal=Biochim. Biophys. Acta |volume=1492 |issue= 2-3 |pages= 460–4 |year= 2000 |pmid= 10899582 |doi=
*cite journal | author=Hartley JL, Temple GF, Brasch MA |title=DNA cloning using in vitro site-specific recombination. |journal=Genome Res. |volume=10 |issue= 11 |pages= 1788–95 |year= 2001 |pmid= 11076863 |doi=
*cite journal | author=Wiemann S, Weil B, Wellenreuther R, "et al." |title=Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs. |journal=Genome Res. |volume=11 |issue= 3 |pages= 422–35 |year= 2001 |pmid= 11230166 |doi= 10.1101/gr.154701
*cite journal | author=Simpson JC, Wellenreuther R, Poustka A, "et al." |title=Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing. |journal=EMBO Rep. |volume=1 |issue= 3 |pages= 287–92 |year= 2001 |pmid= 11256614 |doi= 10.1093/embo-reports/kvd058
*cite journal | author=McLaughlin JN, Thulin CD, Hart SJ, "et al." |title=Regulatory interaction of phosducin-like protein with the cytosolic chaperonin complex. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 12 |pages= 7962–7 |year= 2002 |pmid= 12060742 |doi= 10.1073/pnas.112075699
*cite journal | author=Humrich J, Bermel C, Grubel T, "et al." |title=Regulation of phosducin-like protein by casein kinase 2 and N-terminal splicing. |journal=J. Biol. Chem. |volume=278 |issue= 7 |pages= 4474–81 |year= 2003 |pmid= 12466282 |doi= 10.1074/jbc.M206347200
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Wiemann S, Arlt D, Huber W, "et al." |title=From ORFeome to biology: a functional genomics pipeline. |journal=Genome Res. |volume=14 |issue= 10B |pages= 2136–44 |year= 2004 |pmid= 15489336 |doi= 10.1101/gr.2576704
*cite journal | author=Carter MD, Southwick K, Lukov G, "et al." |title=Identification of phosphorylation sites on phosducin-like protein by QTOF mass spectrometry. |journal=J Biomol Tech |volume=15 |issue= 4 |pages= 257–64 |year= 2005 |pmid= 15585822 |doi=
*cite journal | author=Humrich J, Bermel C, Bünemann M, "et al." |title=Phosducin-like protein regulates G-protein betagamma folding by interaction with tailless complex polypeptide-1alpha: dephosphorylation or splicing of PhLP turns the switch toward regulation of Gbetagamma folding. |journal=J. Biol. Chem. |volume=280 |issue= 20 |pages= 20042–50 |year= 2005 |pmid= 15745879 |doi= 10.1074/jbc.M409233200
*cite journal | author=Lukov GL, Hu T, McLaughlin JN, "et al." |title=Phosducin-like protein acts as a molecular chaperone for G protein betagamma dimer assembly. |journal=EMBO J. |volume=24 |issue= 11 |pages= 1965–75 |year= 2005 |pmid= 15889144 |doi= 10.1038/sj.emboj.7600673
*cite journal | author=Rual JF, Venkatesan K, Hao T, "et al." |title=Towards a proteome-scale map of the human protein-protein interaction network. |journal=Nature |volume=437 |issue= 7062 |pages= 1173–8 |year= 2005 |pmid= 16189514 |doi= 10.1038/nature04209
*cite journal | author=Mehrle A, Rosenfelder H, Schupp I, "et al." |title=The LIFEdb database in 2006. |journal=Nucleic Acids Res. |volume=34 |issue= Database issue |pages= D415–8 |year= 2006 |pmid= 16381901 |doi= 10.1093/nar/gkj139
*cite journal | author=Lukov GL, Baker CM, Ludtke PJ, "et al." |title=Mechanism of assembly of G protein betagamma subunits by protein kinase CK2-phosphorylated phosducin-like protein and the cytosolic chaperonin complex. |journal=J. Biol. Chem. |volume=281 |issue= 31 |pages= 22261–74 |year= 2006 |pmid= 16717095 |doi= 10.1074/jbc.M601590200
*cite journal | author=Olsen JV, Blagoev B, Gnad F, "et al." |title=Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. |journal=Cell |volume=127 |issue= 3 |pages= 635–48 |year= 2006 |pmid= 17081983 |doi= 10.1016/j.cell.2006.09.026PBB_Controls
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