THOC4

THO complex 4, also known as THOC4, is a human gene.cite web | title = Entrez Gene: THOC4 THO complex 4| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=10189| accessdate = ]

PBB_Summary
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summary_text = The protein encoded by this gene is a heat stable, nuclear protein and functions as a molecular chaperone. It is thought to regulate dimerization, DNA binding, and transcriptional activity of basic region-leucine zipper (bZIP) proteins.cite web | title = Entrez Gene: THOC4 THO complex 4| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=10189| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Bruhn L, Munnerlyn A, Grosschedl R |title=ALY, a context-dependent coactivator of LEF-1 and AML-1, is required for TCRalpha enhancer function. |journal=Genes Dev. |volume=11 |issue= 5 |pages= 640–53 |year= 1997 |pmid= 9119228 |doi=
*cite journal | author=Neubauer G, King A, Rappsilber J, "et al." |title=Mass spectrometry and EST-database searching allows characterization of the multi-protein spliceosome complex. |journal=Nat. Genet. |volume=20 |issue= 1 |pages= 46–50 |year= 1998 |pmid= 9731529 |doi= 10.1038/1700
*cite journal | author=Wichmann I, Garcia-Lozano JR, Respaldiza N, "et al." |title=Autoantibodies to transcriptional regulation proteins DEK and ALY in a patient with systemic lupus erythematosus. |journal=Hum. Immunol. |volume=60 |issue= 1 |pages= 57–62 |year= 1999 |pmid= 9952027 |doi=
*cite journal | author=Virbasius CM, Wagner S, Green MR |title=A human nuclear-localized chaperone that regulates dimerization, DNA binding, and transcriptional activity of bZIP proteins. |journal=Mol. Cell |volume=4 |issue= 2 |pages= 219–28 |year= 1999 |pmid= 10488337 |doi=
*cite journal | author=Muravenko OV, Gizatullin RZ, Al-Amin AN, "et al." |title=Human ALY/BEF gene Map position 17q25.3. |journal=Chromosome Res. |volume=8 |issue= 6 |pages= 562 |year= 2001 |pmid= 11032328 |doi=
*cite journal | author=Le Hir H, Izaurralde E, Maquat LE, Moore MJ |title=The spliceosome deposits multiple proteins 20-24 nucleotides upstream of mRNA exon-exon junctions. |journal=EMBO J. |volume=19 |issue= 24 |pages= 6860–9 |year= 2001 |pmid= 11118221 |doi= 10.1093/emboj/19.24.6860
*cite journal | author=Kim VN, Kataoka N, Dreyfuss G |title=Role of the nonsense-mediated decay factor hUpf3 in the splicing-dependent exon-exon junction complex. |journal=Science |volume=293 |issue= 5536 |pages= 1832–6 |year= 2001 |pmid= 11546873 |doi= 10.1126/science.1062829
*cite journal | author=Luo ML, Zhou Z, Magni K, "et al." |title=Pre-mRNA splicing and mRNA export linked by direct interactions between UAP56 and Aly. |journal=Nature |volume=413 |issue= 6856 |pages= 644–7 |year= 2001 |pmid= 11675789 |doi= 10.1038/35098106
*cite journal | author=Kataoka N, Diem MD, Kim VN, "et al." |title=Magoh, a human homolog of Drosophila mago nashi protein, is a component of the splicing-dependent exon-exon junction complex. |journal=EMBO J. |volume=20 |issue= 22 |pages= 6424–33 |year= 2002 |pmid= 11707413 |doi= 10.1093/emboj/20.22.6424
*cite journal | author=Strässer K, Masuda S, Mason P, "et al." |title=TREX is a conserved complex coupling transcription with messenger RNA export. |journal=Nature |volume=417 |issue= 6886 |pages= 304–8 |year= 2002 |pmid= 11979277 |doi= 10.1038/417304a
*cite journal | author=Jurica MS, Licklider LJ, Gygi SR, "et al." |title=Purification and characterization of native spliceosomes suitable for three-dimensional structural analysis. |journal=RNA |volume=8 |issue= 4 |pages= 426–39 |year= 2002 |pmid= 11991638 |doi=
*cite journal | author=Rappsilber J, Ryder U, Lamond AI, Mann M |title=Large-scale proteomic analysis of the human spliceosome. |journal=Genome Res. |volume=12 |issue= 8 |pages= 1231–45 |year= 2002 |pmid= 12176931 |doi= 10.1101/gr.473902
*cite journal | author=Chen IH, Sciabica KS, Sandri-Goldin RM |title=ICP27 interacts with the RNA export factor Aly/REF to direct herpes simplex virus type 1 intronless mRNAs to the TAP export pathway. |journal=J. Virol. |volume=76 |issue= 24 |pages= 12877–89 |year= 2002 |pmid= 12438613 |doi=
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=McCracken S, Longman D, Johnstone IL, "et al." |title=An evolutionarily conserved role for SRm160 in 3'-end processing that functions independently of exon junction complex formation. |journal=J. Biol. Chem. |volume=278 |issue= 45 |pages= 44153–60 |year= 2004 |pmid= 12944400 |doi= 10.1074/jbc.M306856200
*cite journal | author=Pryor A, Tung L, Yang Z, "et al." |title=Growth-regulated expression and G0-specific turnover of the mRNA that encodes URH49, a mammalian DExH/D box protein that is highly related to the mRNA export protein UAP56. |journal=Nucleic Acids Res. |volume=32 |issue= 6 |pages= 1857–65 |year= 2004 |pmid= 15047853 |doi= 10.1093/nar/gkh347
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Ong SE, Mittler G, Mann M |title=Identifying and quantifying in vivo methylation sites by heavy methyl SILAC. |journal=Nat. Methods |volume=1 |issue= 2 |pages= 119–26 |year= 2005 |pmid= 15782174 |doi= 10.1038/nmeth715
*cite journal | author=Masuda S, Das R, Cheng H, "et al." |title=Recruitment of the human TREX complex to mRNA during splicing. |journal=Genes Dev. |volume=19 |issue= 13 |pages= 1512–7 |year= 2005 |pmid= 15998806 |doi= 10.1101/gad.1302205
*cite journal | author=Mertz JA, Kobayashi R, Dudley JP |title=ALY is a common coactivator of RUNX1 and c-Myb on the type B leukemogenic virus enhancer. |journal=J. Virol. |volume=81 |issue= 7 |pages= 3503–13 |year= 2007 |pmid= 17229714 |doi= 10.1128/JVI.02253-06

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