VSNL1

Visinin-like 1, also known as VSNL1, is a human gene.cite web | title = Entrez Gene: VSNL1 visinin-like 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=7447| accessdate = ]

PBB_Summary
section_title =
summary_text = This gene is a member of the visinin/recoverin subfamily of neuronal calcium sensor proteins. The encoded protein is strongly expressed in granule cells of the cerebellum where it associates with membranes in a calcium-dependent manner and modulates intracellular signaling pathways of the central nervous system by directly or indirectly regulating the activity of adenylyl cyclase. Alternatively spliced transcript variants have been observed, but their full-length nature has not been determined.cite web | title = Entrez Gene: VSNL1 visinin-like 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=7447| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Kuno T, Kajimoto Y, Hashimoto T, "et al." |title=cDNA cloning of a neural visinin-like Ca(2+)-binding protein. |journal=Biochem. Biophys. Res. Commun. |volume=184 |issue= 3 |pages= 1219–25 |year= 1992 |pmid= 1375457 |doi=
*cite journal | author=Polymeropoulos MH, Ide S, Soares MB, Lennon GG |title=Sequence characterization and genetic mapping of the human VSNL1 gene, a homologue of the rat visinin-like peptide RNVP1. |journal=Genomics |volume=29 |issue= 1 |pages= 273–5 |year= 1996 |pmid= 8530085 |doi= 10.1006/geno.1995.1244
*cite journal | author=Lenz SE, Braunewell KH, Weise C, "et al." |title=The neuronal EF-hand Ca(2+)-binding protein VILIP: interaction with cell membrane and actin-based cytoskeleton. |journal=Biochem. Biophys. Res. Commun. |volume=225 |issue= 3 |pages= 1078–83 |year= 1996 |pmid= 8780737 |doi= 10.1006/bbrc.1996.1298
*cite journal | author=Braunewell KH, Spilker C, Behnisch T, Gundelfinger ED |title=The neuronal calcium-sensor protein VILIP modulates cyclic AMP accumulation in stably transfected C6 glioma cells: amino-terminal myristoylation determines functional activity. |journal=J. Neurochem. |volume=68 |issue= 5 |pages= 2129–39 |year= 1997 |pmid= 9109541 |doi=
*cite journal | author=Kobayashi M, Sakai E, Furuta Y, Takamatsu K |title=Isolation of two human cDNAs, HLP3 and HLP4, homologous to the neuron-specific calcium-binding protein genes. |journal=DNA Seq. |volume=9 |issue= 3 |pages= 171–6 |year= 1999 |pmid= 10520747 |doi=
*cite journal | author=Bernstein HG, Baumann B, Danos P, "et al." |title=Regional and cellular distribution of neural visinin-like protein immunoreactivities (VILIP-1 and VILIP-3) in human brain. |journal=J. Neurocytol. |volume=28 |issue= 8 |pages= 655–62 |year= 2000 |pmid= 10851344 |doi=
*cite journal | author=Braunewell KH, Brackmann M, Schaupp M, "et al." |title=Intracellular neuronal calcium sensor (NCS) protein VILIP-1 modulates cGMP signalling pathways in transfected neural cells and cerebellar granule neurones. |journal=J. Neurochem. |volume=78 |issue= 6 |pages= 1277–86 |year= 2001 |pmid= 11579136 |doi=
*cite journal | author=Schnurra I, Bernstein HG, Riederer P, Braunewell KH |title=The neuronal calcium sensor protein VILIP-1 is associated with amyloid plaques and extracellular tangles in Alzheimer's disease and promotes cell death and tau phosphorylation in vitro: a link between calcium sensors and Alzheimer's disease? |journal=Neurobiol. Dis. |volume=8 |issue= 5 |pages= 900–9 |year= 2002 |pmid= 11592857 |doi= 10.1006/nbdi.2001.0432
*cite journal | author=Bernstein HG, Braunewell KH, Spilker C, "et al." |title=Hippocampal expression of the calcium sensor protein visinin-like protein-1 in schizophrenia. |journal=Neuroreport |volume=13 |issue= 4 |pages= 393–6 |year= 2002 |pmid= 11930147 |doi=
*cite journal | author=Spilker C, Dresbach T, Braunewell KH |title=Reversible translocation and activity-dependent localization of the calcium-myristoyl switch protein VILIP-1 to different membrane compartments in living hippocampal neurons. |journal=J. Neurosci. |volume=22 |issue= 17 |pages= 7331–9 |year= 2002 |pmid= 12196554 |doi=
*cite journal | author=Lin L, Braunewell KH, Gundelfinger ED, Anand R |title=Functional analysis of calcium-binding EF-hand motifs of visinin-like protein-1. |journal=Biochem. Biophys. Res. Commun. |volume=296 |issue= 4 |pages= 827–32 |year= 2002 |pmid= 12200122 |doi=
*cite journal | author=Lin L, Jeanclos EM, Treuil M, "et al." |title=The calcium sensor protein visinin-like protein-1 modulates the surface expression and agonist sensitivity of the alpha 4beta 2 nicotinic acetylcholine receptor. |journal=J. Biol. Chem. |volume=277 |issue= 44 |pages= 41872–8 |year= 2003 |pmid= 12202488 |doi= 10.1074/jbc.M206857200
*cite journal | author=Spilker C, Gundelfinger ED, Braunewell KH |title=Evidence for different functional properties of the neuronal calcium sensor proteins VILIP-1 and VILIP-3: from subcellular localization to cellular function. |journal=Biochim. Biophys. Acta |volume=1600 |issue= 1-2 |pages= 118–27 |year= 2002 |pmid= 12445467 |doi=
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Braunewell KH, Brackmann M, Manahan-Vaughan D |title=Group I mGlu receptors regulate the expression of the neuronal calcium sensor protein VILIP-1 in vitro and in vivo: implications for mGlu receptor-dependent hippocampal plasticity? |journal=Neuropharmacology |volume=44 |issue= 6 |pages= 707–15 |year= 2003 |pmid= 12681369 |doi=
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Gonzalez Guerrico AM, Jaffer ZM, Page RE, "et al." |title=Visinin-like protein-1 is a potent inhibitor of cell adhesion and migration in squamous carcinoma cells. |journal=Oncogene |volume=24 |issue= 14 |pages= 2307–16 |year= 2005 |pmid= 15735716 |doi= 10.1038/sj.onc.1208476
*cite journal | author=Rual JF, Venkatesan K, Hao T, "et al." |title=Towards a proteome-scale map of the human protein-protein interaction network. |journal=Nature |volume=437 |issue= 7062 |pages= 1173–8 |year= 2005 |pmid= 16189514 |doi= 10.1038/nature04209
*cite journal | author=Jheng FF, Wang L, Lee L, Chang LS |title=Functional contribution of Ca2+ and Mg2+ to the intermolecular interaction of visinin-like proteins. |journal=Protein J. |volume=25 |issue= 4 |pages= 250–6 |year= 2007 |pmid= 16703469 |doi= 10.1007/s10930-006-9008-5
*cite journal | author=Lim J, Hao T, Shaw C, "et al." |title=A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration. |journal=Cell |volume=125 |issue= 4 |pages= 801–14 |year= 2006 |pmid= 16713569 |doi= 10.1016/j.cell.2006.03.032

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