VPS24

Vacuolar protein sorting 24 homolog (S. cerevisiae), also known as VPS24, is a human gene.cite web | title = Entrez Gene: VPS24 vacuolar protein sorting 24 homolog (S. cerevisiae)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=51652| accessdate = ]

PBB_Summary
section_title =
summary_text = This gene encodes a protein that acts in the sorting of transmembrane proteins into lysosomes/vacuoles via the multivesicular body (MVB) pathway. This protein, along with other soluble coiled-coil containing proteins, forms part of the ESCRT-III protein complex that binds to the endosomal membrane and recruits additional cofactors for protein sorting into the MVB. This protein may also co-immunoprecipitate with a member of the IFG-binding protein superfamily. Alternative splicing results in multiple transcript variants encoding different isoforms.cite web | title = Entrez Gene: VPS24 vacuolar protein sorting 24 homolog (S. cerevisiae)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=51652| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Lai CH, Chou CY, Ch'ang LY, "et al." |title=Identification of novel human genes evolutionarily conserved in Caenorhabditis elegans by comparative proteomics. |journal=Genome Res. |volume=10 |issue= 5 |pages= 703–13 |year= 2000 |pmid= 10810093 |doi=
*cite journal | author=Wilson EM, Oh Y, Hwa V, Rosenfeld RG |title=Interaction of IGF-binding protein-related protein 1 with a novel protein, neuroendocrine differentiation factor, results in neuroendocrine differentiation of prostate cancer cells. |journal=J. Clin. Endocrinol. Metab. |volume=86 |issue= 9 |pages= 4504–11 |year= 2001 |pmid= 11549700 |doi=
*cite journal | author=Babst M, Katzmann DJ, Estepa-Sabal EJ, "et al." |title=Escrt-III: an endosome-associated heterooligomeric protein complex required for mvb sorting. |journal=Dev. Cell |volume=3 |issue= 2 |pages= 271–82 |year= 2002 |pmid= 12194857 |doi=
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Su ZZ, Kang DC, Chen Y, "et al." |title=Identification of gene products suppressed by human immunodeficiency virus type 1 infection or gp120 exposure of primary human astrocytes by rapid subtraction hybridization. |journal=J. Neurovirol. |volume=9 |issue= 3 |pages= 372–89 |year= 2003 |pmid= 12775420 |doi=
*cite journal | author=Whitley P, Reaves BJ, Hashimoto M, "et al." |title=Identification of mammalian Vps24p as an effector of phosphatidylinositol 3,5-bisphosphate-dependent endosome compartmentalization. |journal=J. Biol. Chem. |volume=278 |issue= 40 |pages= 38786–95 |year= 2003 |pmid= 12878588 |doi= 10.1074/jbc.M306864200
*cite journal | author=Strack B, Calistri A, Craig S, "et al." |title=AIP1/ALIX is a binding partner for HIV-1 p6 and EIAV p9 functioning in virus budding. |journal=Cell |volume=114 |issue= 6 |pages= 689–99 |year= 2003 |pmid= 14505569 |doi=
*cite journal | author=von Schwedler UK, Stuchell M, Müller B, "et al." |title=The protein network of HIV budding. |journal=Cell |volume=114 |issue= 6 |pages= 701–13 |year= 2003 |pmid= 14505570 |doi=
*cite journal | author=Martin-Serrano J, Yarovoy A, Perez-Caballero D, "et al." |title=Divergent retroviral late-budding domains recruit vacuolar protein sorting factors by using alternative adaptor proteins. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=100 |issue= 21 |pages= 12414–9 |year= 2003 |pmid= 14519844 |doi= 10.1073/pnas.2133846100
*cite journal | author=Colland F, Jacq X, Trouplin V, "et al." |title=Functional proteomics mapping of a human signaling pathway. |journal=Genome Res. |volume=14 |issue= 7 |pages= 1324–32 |year= 2004 |pmid= 15231748 |doi= 10.1101/gr.2334104
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Lin Y, Kimpler LA, Naismith TV, "et al." |title=Interaction of the mammalian endosomal sorting complex required for transport (ESCRT) III protein hSnf7-1 with itself, membranes, and the AAA+ ATPase SKD1. |journal=J. Biol. Chem. |volume=280 |issue= 13 |pages= 12799–809 |year= 2005 |pmid= 15632132 |doi= 10.1074/jbc.M413968200
*cite journal | author=Yan Q, Hunt PR, Frelin L, "et al." |title=mVps24p functions in EGF receptor sorting/trafficking from the early endosome. |journal=Exp. Cell Res. |volume=304 |issue= 1 |pages= 265–73 |year= 2005 |pmid= 15707591 |doi= 10.1016/j.yexcr.2004.11.003
*cite journal | author=Hillier LW, Graves TA, Fulton RS, "et al." |title=Generation and annotation of the DNA sequences of human chromosomes 2 and 4. |journal=Nature |volume=434 |issue= 7034 |pages= 724–31 |year= 2005 |pmid= 15815621 |doi= 10.1038/nature03466
*cite journal | author=Rual JF, Venkatesan K, Hao T, "et al." |title=Towards a proteome-scale map of the human protein-protein interaction network. |journal=Nature |volume=437 |issue= 7062 |pages= 1173–8 |year= 2005 |pmid= 16189514 |doi= 10.1038/nature04209
*cite journal | author=Walker GE, Antoniono RJ, Ross HJ, "et al." |title=Neuroendocrine-like differentiation of non-small cell lung carcinoma cells: regulation by cAMP and the interaction of mac25/IGFBP-rP1 and 25.1. |journal=Oncogene |volume=25 |issue= 13 |pages= 1943–54 |year= 2006 |pmid= 16302002 |doi= 10.1038/sj.onc.1209213
*cite journal | author=Bache KG, Stuffers S, Malerød L, "et al." |title=The ESCRT-III subunit hVps24 is required for degradation but not silencing of the epidermal growth factor receptor. |journal=Mol. Biol. Cell |volume=17 |issue= 6 |pages= 2513–23 |year= 2006 |pmid= 16554368 |doi= 10.1091/mbc.E05-10-0915
*cite journal | author=Tsang HT, Connell JW, Brown SE, "et al." |title=A systematic analysis of human CHMP protein interactions: additional MIT domain-containing proteins bind to multiple components of the human ESCRT III complex. |journal=Genomics |volume=88 |issue= 3 |pages= 333–46 |year= 2006 |pmid= 16730941 |doi= 10.1016/j.ygeno.2006.04.003
*cite journal | author=Olsen JV, Blagoev B, Gnad F, "et al." |title=Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. |journal=Cell |volume=127 |issue= 3 |pages= 635–48 |year= 2006 |pmid= 17081983 |doi= 10.1016/j.cell.2006.09.026
*cite journal | author=Zamborlini A, Usami Y, Radoshitzky SR, "et al." |title=Release of autoinhibition converts ESCRT-III components into potent inhibitors of HIV-1 budding. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=103 |issue= 50 |pages= 19140–5 |year= 2007 |pmid= 17146056 |doi= 10.1073/pnas.0603788103

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