- INADL
InaD-like (Drosophila), also known as INADL, is a human
gene .cite web | title = Entrez Gene: INADL InaD-like (Drosophila)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=10207| accessdate = ]PBB_Summary
section_title =
summary_text = This gene encodes a protein with multiple PDZ domains. PDZ domains mediate protein-protein interactions, and proteins with multiple PDZ domains often organize multimeric complexes at the plasma membrane. This protein localizes to tight junctions and to the apical membrane of epithelial cells. A similar protein in Drosophila is a scaffolding protein which tethers several members of a multimeric signaling complex in photoreceptors.cite web | title = Entrez Gene: INADL InaD-like (Drosophila)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=10207| accessdate = ]References
Further reading
PBB_Further_reading
citations =
*cite journal | author=Fanning AS, Anderson JM |title=PDZ domains: fundamental building blocks in the organization of protein complexes at the plasma membrane. |journal=J. Clin. Invest. |volume=103 |issue= 6 |pages= 767–72 |year= 1999 |pmid= 10079096 |doi=
*cite journal | author=Lennon G, Auffray C, Polymeropoulos M, Soares MB |title=The I.M.A.G.E. Consortium: an integrated molecular analysis of genomes and their expression. |journal=Genomics |volume=33 |issue= 1 |pages= 151–2 |year= 1996 |pmid= 8617505 |doi= 10.1006/geno.1996.0177
*cite journal | author=Philipp S, Flockerzi V |title=Molecular characterization of a novel human PDZ domain protein with homology to INAD from Drosophila melanogaster. |journal=FEBS Lett. |volume=413 |issue= 2 |pages= 243–8 |year= 1997 |pmid= 9280290 |doi=
*cite journal | author=Kurschner C, Mermelstein PG, Holden WT, Surmeier DJ |title=CIPP, a novel multivalent PDZ domain protein, selectively interacts with Kir4.0 family members, NMDA receptor subunits, neurexins, and neuroligins. |journal=Mol. Cell. Neurosci. |volume=11 |issue= 3 |pages= 161–72 |year= 1998 |pmid= 9647694 |doi= 10.1006/mcne.1998.0679
*cite journal | author=Soejima H, Kawamoto S, Akai J, "et al." |title=Isolation of novel heart-specific genes using the BodyMap database. |journal=Genomics |volume=74 |issue= 1 |pages= 115–20 |year= 2001 |pmid= 11374908 |doi= 10.1006/geno.2001.6527
*cite journal | author=Vaccaro P, Brannetti B, Montecchi-Palazzi L, "et al." |title=Distinct binding specificity of the multiple PDZ domains of INADL, a human protein with homology to INAD from Drosophila melanogaster. |journal=J. Biol. Chem. |volume=276 |issue= 45 |pages= 42122–30 |year= 2001 |pmid= 11509564 |doi= 10.1074/jbc.M104208200
*cite journal | author=Anzai N, Deval E, Schaefer L, "et al." |title=The multivalent PDZ domain-containing protein CIPP is a partner of acid-sensing ion channel 3 in sensory neurons. |journal=J. Biol. Chem. |volume=277 |issue= 19 |pages= 16655–61 |year= 2002 |pmid= 11872753 |doi= 10.1074/jbc.M201087200
*cite journal | author=Roh MH, Makarova O, Liu CJ, "et al." |title=The Maguk protein, Pals1, functions as an adapter, linking mammalian homologues of Crumbs and Discs Lost. |journal=J. Cell Biol. |volume=157 |issue= 1 |pages= 161–72 |year= 2002 |pmid= 11927608 |doi= 10.1083/jcb.200109010
*cite journal | author=Lemmers C, Médina E, Delgrossi MH, "et al." |title=hINADl/PATJ, a homolog of discs lost, interacts with crumbs and localizes to tight junctions in human epithelial cells. |journal=J. Biol. Chem. |volume=277 |issue= 28 |pages= 25408–15 |year= 2002 |pmid= 11964389 |doi= 10.1074/jbc.M202196200
*cite journal | author=Roh MH, Liu CJ, Laurinec S, Margolis B |title=The carboxyl terminus of zona occludens-3 binds and recruits a mammalian homologue of discs lost to tight junctions. |journal=J. Biol. Chem. |volume=277 |issue= 30 |pages= 27501–9 |year= 2002 |pmid= 12021270 |doi= 10.1074/jbc.M201177200
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Makarova O, Roh MH, Liu CJ, "et al." |title=Mammalian Crumbs3 is a small transmembrane protein linked to protein associated with Lin-7 (Pals1). |journal=Gene |volume=302 |issue= 1-2 |pages= 21–9 |year= 2003 |pmid= 12527193 |doi=
*cite journal | author=Roh MH, Fan S, Liu CJ, Margolis B |title=The Crumbs3-Pals1 complex participates in the establishment of polarity in mammalian epithelial cells. |journal=J. Cell. Sci. |volume=116 |issue= Pt 14 |pages= 2895–906 |year= 2004 |pmid= 12771187 |doi= 10.1242/jcs.00500
*cite journal | author=Li Y, Karnak D, Demeler B, "et al." |title=Structural basis for L27 domain-mediated assembly of signaling and cell polarity complexes. |journal=EMBO J. |volume=23 |issue= 14 |pages= 2723–33 |year= 2005 |pmid= 15241471 |doi= 10.1038/sj.emboj.7600294
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Michel D, Arsanto JP, Massey-Harroche D, "et al." |title=PATJ connects and stabilizes apical and lateral components of tight junctions in human intestinal cells. |journal=J. Cell. Sci. |volume=118 |issue= Pt 17 |pages= 4049–57 |year= 2005 |pmid= 16129888 |doi= 10.1242/jcs.02528
*cite journal | author=Stiffler MA, Grantcharova VP, Sevecka M, MacBeath G |title=Uncovering quantitative protein interaction networks for mouse PDZ domains using protein microarrays. |journal=J. Am. Chem. Soc. |volume=128 |issue= 17 |pages= 5913–22 |year= 2007 |pmid= 16637659 |doi= 10.1021/ja060943h
*cite journal | author=Wells CD, Fawcett JP, Traweger A, "et al." |title=A Rich1/Amot complex regulates the Cdc42 GTPase and apical-polarity proteins in epithelial cells. |journal=Cell |volume=125 |issue= 3 |pages= 535–48 |year= 2006 |pmid= 16678097 |doi= 10.1016/j.cell.2006.02.045
*cite journal | author=Gregory SG, Barlow KF, McLay KE, "et al." |title=The DNA sequence and biological annotation of human chromosome 1. |journal=Nature |volume=441 |issue= 7091 |pages= 315–21 |year= 2006 |pmid= 16710414 |doi= 10.1038/nature04727PBB_Controls
update_page = yes
require_manual_inspection = no
update_protein_box = yes
update_summary = yes
update_citations = yes
Wikimedia Foundation. 2010.