EHMT2

Euchromatic histone-lysine N-methyltransferase 2, also known as EHMT2, is a human gene.cite web | title = Entrez Gene: EHMT2 euchromatic histone-lysine N-methyltransferase 2| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=10919| accessdate = ]

PBB_Summary
section_title =
summary_text = A cluster of genes, BAT1-BAT5, has been localized in the vicinity of the genes for TNF alpha and TNF beta. This gene is found near this cluster; it was mapped near the gene for C2 within a 120-kb region that included a HSP70 gene pair. These genes are all within the human major histocompatibility complex class III region. This gene was thought to be two different genes, NG36 and G9a, adjacent to each other but a recent publication shows that there is only a single gene. The protein encoded by this gene is thought to be involved in intracellular protein-protein interaction. There are three alternatively spliced transcript variants of this gene but only two are fully described.cite web | title = Entrez Gene: EHMT2 euchromatic histone-lysine N-methyltransferase 2| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=10919| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Spies T, Bresnahan M, Strominger JL |title=Human major histocompatibility complex contains a minimum of 19 genes between the complement cluster and HLA-B. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=86 |issue= 22 |pages= 8955–8 |year= 1989 |pmid= 2813433 |doi=
*cite journal | author=Milner CM, Campbell RD |title=The G9a gene in the human major histocompatibility complex encodes a novel protein containing ankyrin-like repeats. |journal=Biochem. J. |volume=290 ( Pt 3) |issue= |pages= 811–8 |year= 1993 |pmid= 8457211 |doi=
*cite journal | author=Tachibana M, Sugimoto K, Fukushima T, Shinkai Y |title=Set domain-containing protein, G9a, is a novel lysine-preferring mammalian histone methyltransferase with hyperactivity and specific selectivity to lysines 9 and 27 of histone H3. |journal=J. Biol. Chem. |volume=276 |issue= 27 |pages= 25309–17 |year= 2001 |pmid= 11316813 |doi= 10.1074/jbc.M101914200
*cite journal | author=Brown SE, Campbell RD, Sanderson CM |title=Novel NG36/G9a gene products encoded within the human and mouse MHC class III regions. |journal=Mamm. Genome |volume=12 |issue= 12 |pages= 916–24 |year= 2002 |pmid= 11707778 |doi=
*cite journal | author=Ogawa H, Ishiguro K, Gaubatz S, "et al." |title=A complex with chromatin modifiers that occupies E2F- and Myc-responsive genes in G0 cells. |journal=Science |volume=296 |issue= 5570 |pages= 1132–6 |year= 2002 |pmid= 12004135 |doi= 10.1126/science.1069861
*cite journal | author=Tachibana M, Sugimoto K, Nozaki M, "et al." |title=G9a histone methyltransferase plays a dominant role in euchromatic histone H3 lysine 9 methylation and is essential for early embryogenesis. |journal=Genes Dev. |volume=16 |issue= 14 |pages= 1779–91 |year= 2002 |pmid= 12130538 |doi= 10.1101/gad.989402
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Shi Y, Sawada J, Sui G, "et al." |title=Coordinated histone modifications mediated by a CtBP co-repressor complex. |journal=Nature |volume=422 |issue= 6933 |pages= 735–8 |year= 2003 |pmid= 12700765 |doi= 10.1038/nature01550
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*cite journal | author=Roopra A, Qazi R, Schoenike B, "et al." |title=Localized domains of G9a-mediated histone methylation are required for silencing of neuronal genes. |journal=Mol. Cell |volume=14 |issue= 6 |pages= 727–38 |year= 2005 |pmid= 15200951 |doi= 10.1016/j.molcel.2004.05.026
*cite journal | author=Nishio H, Walsh MJ |title=CCAAT displacement protein/cut homolog recruits G9a histone lysine methyltransferase to repress transcription. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=101 |issue= 31 |pages= 11257–62 |year= 2004 |pmid= 15269344 |doi= 10.1073/pnas.0401343101
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Collins RE, Tachibana M, Tamaru H, "et al." |title=In vitro and in vivo analyses of a Phe/Tyr switch controlling product specificity of histone lysine methyltransferases. |journal=J. Biol. Chem. |volume=280 |issue= 7 |pages= 5563–70 |year= 2005 |pmid= 15590646 |doi= 10.1074/jbc.M410483200
*cite journal | author=Rual JF, Venkatesan K, Hao T, "et al." |title=Towards a proteome-scale map of the human protein-protein interaction network. |journal=Nature |volume=437 |issue= 7062 |pages= 1173–8 |year= 2005 |pmid= 16189514 |doi= 10.1038/nature04209
*cite journal | author=Duan Z, Zarebski A, Montoya-Durango D, "et al." |title=Gfi1 coordinates epigenetic repression of p21Cip/WAF1 by recruitment of histone lysine methyltransferase G9a and histone deacetylase 1. |journal=Mol. Cell. Biol. |volume=25 |issue= 23 |pages= 10338–51 |year= 2005 |pmid= 16287849 |doi= 10.1128/MCB.25.23.10338-10351.2005
*cite journal | author=Kimura K, Wakamatsu A, Suzuki Y, "et al." |title=Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. |journal=Genome Res. |volume=16 |issue= 1 |pages= 55–65 |year= 2006 |pmid= 16344560 |doi= 10.1101/gr.4039406
*cite journal | author=Beausoleil SA, Villén J, Gerber SA, "et al." |title=A probability-based approach for high-throughput protein phosphorylation analysis and site localization. |journal=Nat. Biotechnol. |volume=24 |issue= 10 |pages= 1285–92 |year= 2006 |pmid= 16964243 |doi= 10.1038/nbt1240
*cite journal | author=Reeves M, Murphy J, Greaves R, "et al." |title=Autorepression of the human cytomegalovirus major immediate-early promoter/enhancer at late times of infection is mediated by the recruitment of chromatin remodeling enzymes by IE86. |journal=J. Virol. |volume=80 |issue= 20 |pages= 9998–10009 |year= 2006 |pmid= 17005678 |doi= 10.1128/JVI.01297-06
*cite journal | author=Estève PO, Chin HG, Smallwood A, "et al." |title=Direct interaction between DNMT1 and G9a coordinates DNA and histone methylation during replication. |journal=Genes Dev. |volume=20 |issue= 22 |pages= 3089–103 |year= 2006 |pmid= 17085482 |doi= 10.1101/gad.1463706

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