LCN1

Lipocalin 1 (tear prealbumin), also known as LCN1, is a human gene.cite web | title = Entrez Gene: LCN1 lipocalin 1 (tear prealbumin)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=3933| accessdate = ]

PBB_Summary
section_title =
summary_text = The protein encoded by this gene belongs to the lipocalin family. Lipocalins are a group of extracellular proteins that are able to bind lipophiles by enclosure within their structures to minimize solvent contact. This protein may bind hydrophobic ligands and inhibit cysteine proteinases. It may also play a role in taste reception.cite web | title = Entrez Gene: LCN1 lipocalin 1 (tear prealbumin)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=3933| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Glasgow BJ, Abduragimov AR, Gasymov OK, Yusifov TN |title=Tear lipocalin: structure, function and molecular mechanisms of action. |journal=Adv. Exp. Med. Biol. |volume=506 |issue= Pt A |pages= 555–65 |year= 2003 |pmid= 12613960 |doi=
*cite journal | author=Redl B, Holzfeind P, Lottspeich F |title=cDNA cloning and sequencing reveals human tear prealbumin to be a member of the lipophilic-ligand carrier protein superfamily. |journal=J. Biol. Chem. |volume=267 |issue= 28 |pages= 20282–7 |year= 1992 |pmid= 1400345 |doi=
*cite journal | author=Lassagne H, Nguyen VC, Mattei MG, Gachon AM |title=Assignment of LCN1 to human chromosome 9 is confirmed. |journal=Cytogenet. Cell Genet. |volume=71 |issue= 1 |pages= 104 |year= 1995 |pmid= 7606920 |doi=
*cite journal | author=Bläker M, Kock K, Ahlers C, "et al." |title=Molecular cloning of human von Ebner's gland protein, a member of the lipocalin superfamily highly expressed in lingual salivary glands. |journal=Biochim. Biophys. Acta |volume=1172 |issue= 1-2 |pages= 131–7 |year= 1993 |pmid= 7679926 |doi=
*cite journal | author=Holzfeind P, Redl B |title=Structural organization of the gene encoding the human lipocalin tear prealbumin and synthesis of the recombinant protein in Escherichia coli. |journal=Gene |volume=139 |issue= 2 |pages= 177–83 |year= 1994 |pmid= 8112601 |doi=
*cite journal | author=Lassagne H, Ressot C, Mattei MG, Gachon AM |title=Assignment of the human tear lipocalin gene (LCN1) to 9q34 by in situ hybridization. |journal=Genomics |volume=18 |issue= 1 |pages= 160–1 |year= 1994 |pmid= 8276406 |doi= 10.1006/geno.1993.1444
*cite journal | author=Lassagne H, Gachon AM |title=Cloning of a human lacrimal lipocalin secreted in tears. |journal=Exp. Eye Res. |volume=56 |issue= 5 |pages= 605–9 |year= 1993 |pmid= 8500570 |doi=
*cite journal | author=Holzfeind P, Merschak P, Rogatsch H, "et al." |title=Expression of the gene for tear lipocalin/von Ebner's gland protein in human prostate. |journal=FEBS Lett. |volume=395 |issue= 2-3 |pages= 95–8 |year= 1996 |pmid= 8898072 |doi=
*cite journal | author=van't Hof W, Blankenvoorde MF, Veerman EC, Amerongen AV |title=The salivary lipocalin von Ebner's gland protein is a cysteine proteinase inhibitor. |journal=J. Biol. Chem. |volume=272 |issue= 3 |pages= 1837–41 |year= 1997 |pmid= 8999869 |doi=
*cite journal | author=Redl B, Wojnar P, Ellemunter H, Feichtinger H |title=Identification of a lipocalin in mucosal glands of the human tracheobronchial tree and its enhanced secretion in cystic fibrosis. |journal=Lab. Invest. |volume=78 |issue= 9 |pages= 1121–9 |year= 1998 |pmid= 9759656 |doi=
*cite journal | author=Gasymov OK, Abduragimov AR, Yusifov TN, Glasgow BJ |title=Interaction of tear lipocalin with lysozyme and lactoferrin. |journal=Biochem. Biophys. Res. Commun. |volume=265 |issue= 2 |pages= 322–5 |year= 1999 |pmid= 10558865 |doi= 10.1006/bbrc.1999.1668
*cite journal | author=Wojnar P, Lechner M, Merschak P, Redl B |title=Molecular cloning of a novel lipocalin-1 interacting human cell membrane receptor using phage display. |journal=J. Biol. Chem. |volume=276 |issue= 23 |pages= 20206–12 |year= 2001 |pmid= 11287427 |doi= 10.1074/jbc.M101762200
*cite journal | author=Wojnar P, van't Hof W, Merschak P, "et al." |title=The N-terminal part of recombinant human tear lipocalin/von Ebner's gland protein confers cysteine proteinase inhibition depending on the presence of the entire cystatin-like sequence motifs. |journal=Biol. Chem. |volume=382 |issue= 10 |pages= 1515–20 |year= 2002 |pmid= 11727836 |doi=
*cite journal | author=Wojnar P, Dirnhofer S, Ladurner P, "et al." |title=Human lipocalin-1, a physiological scavenger of lipophilic compounds, is produced by corticotrophs of the pituitary gland. |journal=J. Histochem. Cytochem. |volume=50 |issue= 3 |pages= 433–5 |year= 2002 |pmid= 11850445 |doi=
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Wojnar P, Lechner M, Redl B |title=Antisense down-regulation of lipocalin-interacting membrane receptor expression inhibits cellular internalization of lipocalin-1 in human NT2 cells. |journal=J. Biol. Chem. |volume=278 |issue= 18 |pages= 16209–15 |year= 2003 |pmid= 12591932 |doi= 10.1074/jbc.M210922200
*cite journal | author=Glasgow BJ, Abduragimov AR, Gassymov OK, "et al." |title=Vitamin E associated with the lipocalin fraction of human tears. |journal=Adv. Exp. Med. Biol. |volume=506 |issue= Pt A |pages= 567–72 |year= 2003 |pmid= 12613961 |doi=
*cite journal | author=Tiffany JM, Nagyová B |title=The role of lipocalin in determining the physical properties of tears. |journal=Adv. Exp. Med. Biol. |volume=506 |issue= Pt A |pages= 581–5 |year= 2003 |pmid= 12613963 |doi=
*cite journal | author=Gasymov OK, Abduragimov AR, Yusifov TN, Glasgow BJ |title=Interstrand loops CD and EF act as pH-dependent gates to regulate fatty acid ligand binding in tear lipocalin. |journal=Biochemistry |volume=43 |issue= 40 |pages= 12894–904 |year= 2004 |pmid= 15461462 |doi= 10.1021/bi049076o

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