ISL1

ISL1 transcription factor, LIM/homeodomain, (islet-1), also known as ISL1, is a human gene.cite web | title = Entrez Gene: ISL1 ISL1 transcription factor, LIM/homeodomain, (islet-1)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=3670| accessdate = ]

PBB_Summary
section_title =
summary_text = This gene encodes a transcription factor containing two N-terminal LIM domains and one C-terminal homeodomain. The encoded protein plays an important role in the embryogenesis of pancreatic islets of Langerhans. In mouse embryos, a deficiency of this gene fail to undergo neural tube motor neuron differentiation.cite web | title = Entrez Gene: ISL1 ISL1 transcription factor, LIM/homeodomain, (islet-1)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=3670| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Larsson LI |title=On the development of the islets of Langerhans. |journal=Microsc. Res. Tech. |volume=43 |issue= 4 |pages= 284–91 |year= 1999 |pmid= 9849969 |doi= 10.1002/(SICI)1097-0029(19981115)43:4<284::AID-JEMT2>3.0.CO;2-0 |doilabel=10.1002/(SICI)1097-0029(19981115)43:4284::AID-JEMT23.0.CO;2-0
*cite journal | author=Dong J, Asa SL, Drucker DJ |title=Islet cell and extrapancreatic expression of the LIM domain homeobox gene isl-1. |journal=Mol. Endocrinol. |volume=5 |issue= 11 |pages= 1633–41 |year= 1992 |pmid= 1685766 |doi=
*cite journal | author=Riggs AC, Tanizawa Y, Aoki M, "et al." |title=Characterization of the LIM/homeodomain gene islet-1 and single nucleotide screening in NIDDM. |journal=Diabetes |volume=44 |issue= 6 |pages= 689–94 |year= 1995 |pmid= 7789634 |doi=
*cite journal | author=Wang M, Drucker DJ |title=The LIM domain homeobox gene isl-1: conservation of human, hamster, and rat complementary deoxyribonucleic acid sequences and expression in cell types of nonneuroendocrine lineage. |journal=Endocrinology |volume=134 |issue= 3 |pages= 1416–22 |year= 1994 |pmid= 7907017 |doi=
*cite journal | author=Tanizawa Y, Riggs AC, Dagogo-Jack S, "et al." |title=Isolation of the human LIM/homeodomain gene islet-1 and identification of a simple sequence repeat polymorphism [corrected] |journal=Diabetes |volume=43 |issue= 7 |pages= 935–41 |year= 1994 |pmid= 7912209 |doi=
*cite journal | author=Pfaff SL, Mendelsohn M, Stewart CL, "et al." |title=Requirement for LIM homeobox gene Isl1 in motor neuron generation reveals a motor neuron-dependent step in interneuron differentiation. |journal=Cell |volume=84 |issue= 2 |pages= 309–20 |year= 1996 |pmid= 8565076 |doi=
*cite journal | author=Bonaldo MF, Lennon G, Soares MB |title=Normalization and subtraction: two approaches to facilitate gene discovery. |journal=Genome Res. |volume=6 |issue= 9 |pages= 791–806 |year= 1997 |pmid= 8889548 |doi=
*cite journal | author=Ahlgren U, Pfaff SL, Jessell TM, "et al." |title=Independent requirement for ISL1 in formation of pancreatic mesenchyme and islet cells. |journal=Nature |volume=385 |issue= 6613 |pages= 257–60 |year= 1997 |pmid= 9000074 |doi= 10.1038/385257a0
*cite journal | author=Jurata LW, Pfaff SL, Gill GN |title=The nuclear LIM domain interactor NLI mediates homo- and heterodimerization of LIM domain transcription factors. |journal=J. Biol. Chem. |volume=273 |issue= 6 |pages= 3152–7 |year= 1998 |pmid= 9452425 |doi=
*cite journal | author=Bach I, Rodriguez-Esteban C, Carrière C, "et al." |title=RLIM inhibits functional activity of LIM homeodomain transcription factors via recruitment of the histone deacetylase complex. |journal=Nat. Genet. |volume=22 |issue= 4 |pages= 394–9 |year= 1999 |pmid= 10431247 |doi= 10.1038/11970
*cite journal | author=Gay F, Anglade I, Gong Z, Salbert G |title=The LIM/homeodomain protein islet-1 modulates estrogen receptor functions. |journal=Mol. Endocrinol. |volume=14 |issue= 10 |pages= 1627–48 |year= 2001 |pmid= 11043578 |doi=
*cite journal | author=Ostendorff HP, Peirano RI, Peters MA, "et al." |title=Ubiquitination-dependent cofactor exchange on LIM homeodomain transcription factors. |journal=Nature |volume=416 |issue= 6876 |pages= 99–103 |year= 2002 |pmid= 11882901 |doi= 10.1038/416099a
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Holm P, Rydlander B, Luthman H, "et al." |title=Interaction and association analysis of a type 1 diabetes susceptibility locus on chromosome 5q11-q13 and the 7q32 chromosomal region in Scandinavian families. |journal=Diabetes |volume=53 |issue= 6 |pages= 1584–91 |year= 2004 |pmid= 15161765 |doi=
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Hori Y, Gu X, Xie X, Kim SK |title=Differentiation of insulin-producing cells from human neural progenitor cells. |journal=PLoS Med. |volume=2 |issue= 4 |pages= e103 |year= 2006 |pmid= 15839736 |doi= 10.1371/journal.pmed.0020103
*cite journal | author=Takeuchi JK, Mileikovskaia M, Koshiba-Takeuchi K, "et al." |title=Tbx20 dose-dependently regulates transcription factor networks required for mouse heart and motoneuron development. |journal=Development |volume=132 |issue= 10 |pages= 2463–74 |year= 2005 |pmid= 15843409 |doi= 10.1242/dev.01827
*cite journal | author=Rual JF, Venkatesan K, Hao T, "et al." |title=Towards a proteome-scale map of the human protein-protein interaction network. |journal=Nature |volume=437 |issue= 7062 |pages= 1173–8 |year= 2005 |pmid= 16189514 |doi= 10.1038/nature04209
*cite journal | author=Peng SY, Wang WP, Meng J, "et al." |title=ISL1 physically interacts with BETA2 to promote insulin gene transcriptional synergy in non-beta cells. |journal=Biochim. Biophys. Acta |volume=1731 |issue= 3 |pages= 154–9 |year= 2006 |pmid= 16321656 |doi= 10.1016/j.bbaexp.2005.08.013

External links

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PBB_Controls
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