HAGH

Hydroxyacylglutathione hydrolase, also known as HAGH, is a human gene.cite web | title = Entrez Gene: HAGH hydroxyacylglutathione hydrolase| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=3029| accessdate = ]

PBB_Summary
section_title =
summary_text = The enzyme encoded by this gene is classified as a thiolesterase and is responsible for the hydrolysis of S-lactoyl-glutathione to reduced glutathione and D-lactate.cite web | title = Entrez Gene: HAGH hydroxyacylglutathione hydrolase| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=3029| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Kar NC, Pearson CM |title=Glyoxalase enzyme system in human muscular dystrophy. |journal=Clin. Chim. Acta |volume=65 |issue= 1 |pages= 153–5 |year= 1976 |pmid= 1192606 |doi=
*cite journal | author=Hamilton DS, Creighton DJ |title=Inhibition of glyoxalase I by the enediol mimic S-(N-hydroxy-N-methylcarbamoyl)glutathione. The possible basis of a tumor-selective anticancer strategy. |journal=J. Biol. Chem. |volume=267 |issue= 35 |pages= 24933–6 |year= 1993 |pmid= 1459997 |doi=
*cite journal | author=Mulley JC, Barton N, Callen DF |title=Localisation of human PGP and HAGH genes to 16p13.3. |journal=Cytogenet. Cell Genet. |volume=53 |issue= 2-3 |pages= 175–6 |year= 1990 |pmid= 2164460 |doi=
*cite journal | author=Mulley JC, Callen DF |title=New regional localisations for HAGH and PGP on human chromosome 16. |journal=Hum. Genet. |volume=74 |issue= 4 |pages= 423–4 |year= 1987 |pmid= 3025077 |doi=
*cite journal | author=Talesa V, Uotila L, Koivusalo M, "et al." |title=Demonstration of glyoxalase II in rat liver mitochondria. Partial purification and occurrence in multiple forms. |journal=Biochim. Biophys. Acta |volume=955 |issue= 1 |pages= 103–10 |year= 1988 |pmid= 3382669 |doi=
*cite journal | author=Thornalley PJ, Bellavite P |title=Modification of the glyoxalase system during the functional activation of human neutrophils. |journal=Biochim. Biophys. Acta |volume=931 |issue= 2 |pages= 120–9 |year= 1987 |pmid= 3663711 |doi=
*cite journal | author=Valentine WN, Paglia DE, Neerhout RC, Konrad PN |title=Erythrocyte glyoxalase II deficiency with coincidental hereditary elliptocytosis. |journal=Blood |volume=36 |issue= 6 |pages= 797–808 |year= 1971 |pmid= 5485124 |doi=
*cite journal | author=Leoncini G, Maresca M, Balestrero F, "et al." |title=Platelet glyoxalases in thrombocytosis. |journal=Scandinavian journal of haematology |volume=33 |issue= 1 |pages= 91–4 |year= 1984 |pmid= 6463589 |doi=
*cite journal | author=Honey NK, Shows TB |title=Assignment of the glyoxalase II gene (HAGH) to human chromosome 16. |journal=Hum. Genet. |volume=58 |issue= 4 |pages= 358–61 |year= 1982 |pmid= 7327557 |doi=
*cite journal | author=Board PG |title=Genetic polymorphism of human erythrocyte glyoxalase II. |journal=Am. J. Hum. Genet. |volume=32 |issue= 5 |pages= 690–4 |year= 1980 |pmid= 7424909 |doi=
*cite journal | author=Di Ilio C, Angelucci S, Pennelli A, "et al." |title=Glyoxalase activities in tumor and non-tumor human urogenital tissues. |journal=Cancer Lett. |volume=96 |issue= 2 |pages= 189–93 |year= 1995 |pmid= 7585456 |doi=
*cite journal | author=Ridderström M, Saccucci F, Hellman U, "et al." |title=Molecular cloning, heterologous expression, and characterization of human glyoxalase II. |journal=J. Biol. Chem. |volume=271 |issue= 1 |pages= 319–23 |year= 1996 |pmid= 8550579 |doi=
*cite journal | author=Cameron AD, Ridderström M, Olin B, Mannervik B |title=Crystal structure of human glyoxalase II and its complex with a glutathione thiolester substrate analogue. |journal=Structure |volume=7 |issue= 9 |pages= 1067–78 |year= 1999 |pmid= 10508780 |doi=
*cite journal | author=Daniels RJ, Peden JF, Lloyd C, "et al." |title=Sequence, structure and pathology of the fully annotated terminal 2 Mb of the short arm of human chromosome 16. |journal=Hum. Mol. Genet. |volume=10 |issue= 4 |pages= 339–52 |year= 2001 |pmid= 11157797 |doi=
*cite journal | author=Rulli A, Carli L, Romani R, "et al." |title=Expression of glyoxalase I and II in normal and breast cancer tissues. |journal=Breast Cancer Res. Treat. |volume=66 |issue= 1 |pages= 67–72 |year= 2001 |pmid= 11368412 |doi=
*cite journal | author=Scirè A, Saccucci F, Bertoli E, "et al." |title=Effect of acidic phospholipids on the structural properties of recombinant cytosolic human glyoxalase II. |journal=Proteins |volume=48 |issue= 1 |pages= 126–33 |year= 2002 |pmid= 12012344 |doi= 10.1002/prot.10149
*cite journal | author=Mearini E, Romani R, Mearini L, "et al." |title=Differing expression of enzymes of the glyoxalase system in superficial and invasive bladder carcinomas. |journal=Eur. J. Cancer |volume=38 |issue= 14 |pages= 1946–50 |year= 2002 |pmid= 12204678 |doi=
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Cordell PA, Futers TS, Grant PJ, Pease RJ |title=The Human hydroxyacylglutathione hydrolase (HAGH) gene encodes both cytosolic and mitochondrial forms of glyoxalase II. |journal=J. Biol. Chem. |volume=279 |issue= 27 |pages= 28653–61 |year= 2004 |pmid= 15117945 |doi= 10.1074/jbc.M403470200
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504

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