MAGEA3

Melanoma antigen family A, 3, also known as MAGEA3, is a human gene.cite web | title = Entrez Gene: MAGEA3 melanoma antigen family A, 3| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=4102| accessdate = ]

PBB_Summary
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summary_text = This gene is a member of the MAGEA gene family. The members of this family encode proteins with 50 to 80% sequence identity to each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are clustered at chromosomal location Xq28. They have been implicated in some hereditary disorders, such as dyskeratosis congenita.cite web | title = Entrez Gene: MAGEA3 melanoma antigen family A, 3| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=4102| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=van der Bruggen P, Traversari C, Chomez P, "et al." |title=A gene encoding an antigen recognized by cytolytic T lymphocytes on a human melanoma. |journal=Science |volume=254 |issue= 5038 |pages= 1643–7 |year= 1992 |pmid= 1840703 |doi=
*cite journal | author=Brasseur F, Rimoldi D, Liénard D, "et al." |title=Expression of MAGE genes in primary and metastatic cutaneous melanoma. |journal=Int. J. Cancer |volume=63 |issue= 3 |pages= 375–80 |year= 1995 |pmid= 7591235 |doi=
*cite journal | author=Kocher T, Schultz-Thater E, Gudat F, "et al." |title=Identification and intracellular location of MAGE-3 gene product. |journal=Cancer Res. |volume=55 |issue= 11 |pages= 2236–9 |year= 1995 |pmid= 7757970 |doi=
*cite journal | author=De Plaen E, Arden K, Traversari C, "et al." |title=Structure, chromosomal localization, and expression of 12 genes of the MAGE family. |journal=Immunogenetics |volume=40 |issue= 5 |pages= 360–9 |year= 1994 |pmid= 7927540 |doi=
*cite journal | author=Ding M, Beck RJ, Keller CJ, Fenton RG |title=Cloning and analysis of MAGE-1-related genes. |journal=Biochem. Biophys. Res. Commun. |volume=202 |issue= 1 |pages= 549–55 |year= 1994 |pmid= 8037761 |doi= 10.1006/bbrc.1994.1963
*cite journal | author=Gaugler B, Van den Eynde B, van der Bruggen P, "et al." |title=Human gene MAGE-3 codes for an antigen recognized on a melanoma by autologous cytolytic T lymphocytes. |journal=J. Exp. Med. |volume=179 |issue= 3 |pages= 921–30 |year= 1994 |pmid= 8113684 |doi=
*cite journal | author=Maruyama K, Sugano S |title=Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides. |journal=Gene |volume=138 |issue= 1-2 |pages= 171–4 |year= 1994 |pmid= 8125298 |doi=
*cite journal | author=Rogner UC, Wilke K, Steck E, "et al." |title=The melanoma antigen gene (MAGE) family is clustered in the chromosomal band Xq28. |journal=Genomics |volume=29 |issue= 3 |pages= 725–31 |year= 1996 |pmid= 8575766 |doi= 10.1006/geno.1995.9945
*cite journal | author=Valmori D, Liénard D, Waanders G, "et al." |title=Analysis of MAGE-3-specific cytolytic T lymphocytes in human leukocyte antigen-A2 melanoma patients. |journal=Cancer Res. |volume=57 |issue= 4 |pages= 735–41 |year= 1997 |pmid= 9044853 |doi=
*cite journal | author=Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, "et al." |title=Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library. |journal=Gene |volume=200 |issue= 1-2 |pages= 149–56 |year= 1997 |pmid= 9373149 |doi=
*cite journal | author=Mallon AM, Platzer M, Bate R, "et al." |title=Comparative genome sequence analysis of the Bpa/Str region in mouse and Man. |journal=Genome Res. |volume=10 |issue= 6 |pages= 758–75 |year= 2000 |pmid= 10854409 |doi=
*cite journal | author=Jang SJ, Soria JC, Wang L, "et al." |title=Activation of melanoma antigen tumor antigens occurs early in lung carcinogenesis. |journal=Cancer Res. |volume=61 |issue= 21 |pages= 7959–63 |year= 2001 |pmid= 11691819 |doi=
*cite journal | author=Consogno G, Manici S, Facchinetti V, "et al." |title=Identification of immunodominant regions among promiscuous HLA-DR-restricted CD4+ T-cell epitopes on the tumor antigen MAGE-3. |journal=Blood |volume=101 |issue= 3 |pages= 1038–44 |year= 2003 |pmid= 12393675 |doi= 10.1182/blood-2002-03-0933
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Guo J, Wen DR, Huang RR, "et al." |title=Detection of multiple melanoma-associated markers in melanoma cell lines by RT in situ PCR. |journal=Exp. Mol. Pathol. |volume=74 |issue= 2 |pages= 140–7 |year= 2003 |pmid= 12710945 |doi=
*cite journal | author=Zerbini A, Pilli M, Soliani P, "et al." |title=Ex vivo characterization of tumor-derived melanoma antigen encoding gene-specific CD8+cells in patients with hepatocellular carcinoma. |journal=J. Hepatol. |volume=40 |issue= 1 |pages= 102–9 |year= 2004 |pmid= 14672620 |doi=
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Zhou M, Peng JR, Zhang HG, "et al." |title=Identification of two naturally presented MAGE antigenic peptides from a patient with hepatocellular carcinoma by mass spectrometry. |journal=Immunol. Lett. |volume=99 |issue= 1 |pages= 113–21 |year= 2005 |pmid= 15885805 |doi= 10.1016/j.imlet.2005.02.007
*cite journal | author=Hudolin T, Juretic A, Spagnoli GC, "et al." |title=Immunohistochemical expression of tumor antigens MAGE-A1, MAGE-A3/4, and NY-ESO-1 in cancerous and benign prostatic tissue. |journal=Prostate |volume=66 |issue= 1 |pages= 13–8 |year= 2006 |pmid= 16114059 |doi= 10.1002/pros.20312
*cite journal | author=Miyagawa N, Kono K, Mimura K, "et al." |title=A newly identified MAGE-3-derived, HLA-A24-restricted peptide is naturally processed and presented as a CTL epitope on MAGE-3-expressing gastrointestinal cancer cells. |journal=Oncology |volume=70 |issue= 1 |pages= 54–62 |year= 2006 |pmid= 16446550 |doi= 10.1159/000091185

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