HIST1H1B

Histone cluster 1, H1b, also known as HIST1H1B, is a human gene.cite web | title = Entrez Gene: HIST1H1B histone cluster 1, H1b| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=3009| accessdate = ]

PBB_Summary
section_title =
summary_text = Histones are basic nuclear proteins responsible for nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a member of the histone H1 family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the small histone gene cluster on chromosome 6p22-p21.3.cite web | title = Entrez Gene: HIST1H1B histone cluster 1, H1b| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=3009| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Ohe Y, Hayashi H, Iwai K |title=Human spleen histone H1. Isolation and amino acid sequences of three minor variants, H1a, H1c, and H1d. |journal=J. Biochem. |volume=106 |issue= 5 |pages= 844–57 |year= 1990 |pmid= 2613692 |doi=
*cite journal | author=van Wijnen AJ, Wright KL, Massung RF, "et al." |title=Two target sites for protein binding in the promoter region of a cell cycle regulated human H1 histone gene. |journal=Nucleic Acids Res. |volume=16 |issue= 2 |pages= 571–92 |year= 1988 |pmid= 2829131 |doi=
*cite journal | author=Collar DG, Wright KL, van Wijnen AJ, "et al." |title=The human H1 histone gene FNC16 is functionally expressed in proliferating HeLa S3 cells and is down-regulated during terminal differentiation in HL60 cells. |journal=J. Biol. Chem. |volume=263 |issue= 31 |pages= 15860–3 |year= 1988 |pmid= 3182772 |doi=
*cite journal | author=Ohe Y, Hayashi H, Iwai K |title=Human spleen histone H1. Isolation and amino acid sequence of a main variant, H1b. |journal=J. Biochem. |volume=100 |issue= 2 |pages= 359–68 |year= 1986 |pmid= 3782055 |doi=
*cite journal | author=Carozzi N, Marashi F, Plumb M, "et al." |title=Clustering of human H1 and core histone genes. |journal=Science |volume=224 |issue= 4653 |pages= 1115–7 |year= 1984 |pmid= 6719136 |doi=
*cite journal | author=Aprelikova O, Xiong Y, Liu ET |title=Both p16 and p21 families of cyclin-dependent kinase (CDK) inhibitors block the phosphorylation of cyclin-dependent kinases by the CDK-activating kinase. |journal=J. Biol. Chem. |volume=270 |issue= 31 |pages= 18195–7 |year= 1995 |pmid= 7629134 |doi=
*cite journal | author=Albig W, Drabent B, Kunz J, "et al." |title=All known human H1 histone genes except the H1(0) gene are clustered on chromosome 6. |journal=Genomics |volume=16 |issue= 3 |pages= 649–54 |year= 1993 |pmid= 8325638 |doi= 10.1006/geno.1993.1243
*cite journal | author=Albig W, Meergans T, Doenecke D |title=Characterization of the H1.5 gene completes the set of human H1 subtype genes. |journal=Gene |volume=184 |issue= 2 |pages= 141–8 |year= 1997 |pmid= 9031620 |doi=
*cite journal | author=Albig W, Kioschis P, Poustka A, "et al." |title=Human histone gene organization: nonregular arrangement within a large cluster. |journal=Genomics |volume=40 |issue= 2 |pages= 314–22 |year= 1997 |pmid= 9119399 |doi= 10.1006/geno.1996.4592
*cite journal | author=Albig W, Doenecke D |title=The human histone gene cluster at the D6S105 locus. |journal=Hum. Genet. |volume=101 |issue= 3 |pages= 284–94 |year= 1998 |pmid= 9439656 |doi=
*cite journal | author=New L, Zhao M, Li Y, "et al." |title=Cloning and characterization of RLPK, a novel RSK-related protein kinase. |journal=J. Biol. Chem. |volume=274 |issue= 2 |pages= 1026–32 |year= 1999 |pmid= 9873047 |doi=
*cite journal | author=Chadwick BP, Willard HF |title=A novel chromatin protein, distantly related to histone H2A, is largely excluded from the inactive X chromosome. |journal=J. Cell Biol. |volume=152 |issue= 2 |pages= 375–84 |year= 2001 |pmid= 11266453 |doi=
*cite journal | author=Marzluff WF, Gongidi P, Woods KR, "et al." |title=The human and mouse replication-dependent histone genes. |journal=Genomics |volume=80 |issue= 5 |pages= 487–98 |year= 2003 |pmid= 12408966 |doi=
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Giampuzzi M, Oleggini R, Di Donato A |title=Demonstration of in vitro interaction between tumor suppressor lysyl oxidase and histones H1 and H2: definition of the regions involved. |journal=Biochim. Biophys. Acta |volume=1647 |issue= 1-2 |pages= 245–51 |year= 2003 |pmid= 12686141 |doi=
*cite journal | author=Mungall AJ, Palmer SA, Sims SK, "et al." |title=The DNA sequence and analysis of human chromosome 6. |journal=Nature |volume=425 |issue= 6960 |pages= 805–11 |year= 2003 |pmid= 14574404 |doi= 10.1038/nature02055
*cite journal | author=Vaquero A, Scher M, Lee D, "et al." |title=Human SirT1 interacts with histone H1 and promotes formation of facultative heterochromatin. |journal=Mol. Cell |volume=16 |issue= 1 |pages= 93–105 |year= 2004 |pmid= 15469825 |doi= 10.1016/j.molcel.2004.08.031
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Garcia BA, Busby SA, Barber CM, "et al." |title=Characterization of phosphorylation sites on histone H1 isoforms by tandem mass spectrometry. |journal=J. Proteome Res. |volume=3 |issue= 6 |pages= 1219–27 |year= 2005 |pmid= 15595731 |doi= 10.1021/pr0498887
*cite journal | author=Andersen JS, Lam YW, Leung AK, "et al." |title=Nucleolar proteome dynamics. |journal=Nature |volume=433 |issue= 7021 |pages= 77–83 |year= 2005 |pmid= 15635413 |doi= 10.1038/nature03207

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