ALDH3A1

ALDH3A1

Aldehyde dehydrogenase 3 family, memberA1, also known as ALDH3A1, is a human gene.cite web | title = Entrez Gene: ALDH3A1 aldehyde dehydrogenase 3 family, memberA1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=218| accessdate = ]

PBB_Summary
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summary_text = Aldehyde dehydrogenases oxidize various aldehydes to the corresponding acids. They are involved in the detoxification of alcohol-derived acetaldehyde and in the metabolism of corticosteroids, biogenic amines, neurotransmitters, and lipid peroxidation. The enzyme encoded by this gene forms a cytoplasmic homodimer that preferentially oxidizes aromatic aldehyde substrates. The gene is located within the Smith-Magenis syndrome region on chromosome 17.cite web | title = Entrez Gene: ALDH3A1 aldehyde dehydrogenase 3 family, memberA1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=218| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Yoshida A |title=Molecular genetics of human aldehyde dehydrogenase. |journal=Pharmacogenetics |volume=2 |issue= 4 |pages= 139–47 |year= 1993 |pmid= 1306115 |doi=
*cite journal | author=Vasiliou V, Bairoch A, Tipton KF, Nebert DW |title=Eukaryotic aldehyde dehydrogenase (ALDH) genes: human polymorphisms, and recommended nomenclature based on divergent evolution and chromosomal mapping. |journal=Pharmacogenetics |volume=9 |issue= 4 |pages= 421–34 |year= 2000 |pmid= 10780262 |doi=
*cite journal | author=Hsu LC, Chang WC, Shibuya A, Yoshida A |title=Human stomach aldehyde dehydrogenase cDNA and genomic cloning, primary structure, and expression in Escherichia coli. |journal=J. Biol. Chem. |volume=267 |issue= 5 |pages= 3030–7 |year= 1992 |pmid= 1737758 |doi=
*cite journal | author=Eckey R, Timmann R, Hempel J, "et al." |title=Biochemical, immunological, and molecular characterization of a "high Km" aldehyde dehydrogenase. |journal=Adv. Exp. Med. Biol. |volume=284 |issue= |pages= 43–52 |year= 1991 |pmid= 1905102 |doi=
*cite journal | author=Yin SJ, Vagelopoulos N, Wang SL, Jörnvall H |title=Structural features of stomach aldehyde dehydrogenase distinguish dimeric aldehyde dehydrogenase as a 'variable' enzyme. 'Variable' and 'constant' enzymes within the alcohol and aldehyde dehydrogenase families. |journal=FEBS Lett. |volume=283 |issue= 1 |pages= 85–8 |year= 1991 |pmid= 2037078 |doi=
*cite journal | author=Santisteban I, Povey S, West LF, "et al." |title=Chromosome assignment, biochemical and immunological studies on a human aldehyde dehydrogenase, ALDH3. |journal=Ann. Hum. Genet. |volume=49 |issue= Pt 2 |pages= 87–100 |year= 1986 |pmid= 4073832 |doi=
*cite journal | author=Teng YS |title=Stomach aldehyde dehydrogenase: report of a new locus. |journal=Hum. Hered. |volume=31 |issue= 2 |pages= 74–7 |year= 1981 |pmid= 7228061 |doi=
*cite journal | author=Dyck LE |title=Polymorphism of a class 3 aldehyde dehydrogenase present in human saliva and in hair roots. |journal=Alcohol. Clin. Exp. Res. |volume=19 |issue= 2 |pages= 420–6 |year= 1995 |pmid= 7625577 |doi=
*cite journal | author=Hiraoka LR, Hsu L, Hsieh CL |title=Assignment of ALDH3 to human chromosome 17p11.2 and ALDH5 to human chromosome 9p13. |journal=Genomics |volume=25 |issue= 1 |pages= 323–5 |year= 1995 |pmid= 7774944 |doi=
*cite journal | author=Maruyama K, Sugano S |title=Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides. |journal=Gene |volume=138 |issue= 1-2 |pages= 171–4 |year= 1994 |pmid= 8125298 |doi=
*cite journal | author=Hsu LC, Yoshida A |title=Human stomach aldehyde dehydrogenase, ALDH3. |journal=Adv. Exp. Med. Biol. |volume=328 |issue= |pages= 141–52 |year= 1993 |pmid= 8493892 |doi=
*cite journal | author=Rogers GR, Markova NG, De Laurenzi V, "et al." |title=Genomic organization and expression of the human fatty aldehyde dehydrogenase gene (FALDH). |journal=Genomics |volume=39 |issue= 2 |pages= 127–35 |year= 1997 |pmid= 9027499 |doi= 10.1006/geno.1996.4501
*cite journal | author=Tsukamoto N, Chang C, Yoshida A |title=Mutations associated with Sjögren-Larsson syndrome. |journal=Ann. Hum. Genet. |volume=61 |issue= Pt 3 |pages= 235–42 |year= 1997 |pmid= 9250352 |doi= 10.1046/j.1469-1809.1997.6130235.x
*cite journal | author=Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, "et al." |title=Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library. |journal=Gene |volume=200 |issue= 1-2 |pages= 149–56 |year= 1997 |pmid= 9373149 |doi=
*cite journal | author=Rekha GK, Devaraj VR, Sreerama L, "et al." |title=Inhibition of human class 3 aldehyde dehydrogenase, and sensitization of tumor cells that express significant amounts of this enzyme to oxazaphosphorines, by chlorpropamide analogues. |journal=Biochem. Pharmacol. |volume=55 |issue= 4 |pages= 465–74 |year= 1998 |pmid= 9514081 |doi=
*cite journal | author=Simpson JC, Wellenreuther R, Poustka A, "et al." |title=Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing. |journal=EMBO Rep. |volume=1 |issue= 3 |pages= 287–92 |year= 2001 |pmid= 11256614 |doi= 10.1093/embo-reports/kvd058
*cite journal | author=Rodriguez-Zavala JS, Weiner H |title=Structural aspects of aldehyde dehydrogenase that influence dimer-tetramer formation. |journal=Biochemistry |volume=41 |issue= 26 |pages= 8229–37 |year= 2002 |pmid= 12081471 |doi=
*cite journal | author=Yang M, Coles BF, Delongchamp R, "et al." |title=Effects of the ADH3, CYP2E1, and GSTP1 genetic polymorphisms on their expressions in Caucasian lung tissue. |journal=Lung Cancer |volume=38 |issue= 1 |pages= 15–21 |year= 2003 |pmid= 12367788 |doi=

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