BRD2

Bromodomain containing 2, also known as BRD2, is a human gene.cite web | title = Entrez Gene: BRD2 bromodomain containing 2| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=6046| accessdate = ]

PBB_Summary
section_title =
summary_text = This gene encodes a mitogen-activated kinase which localizes to the nucleus. The gene maps to the major histocompatability complex (MHC) class II region on chromosome 6p21.3 but sequence comparison suggests that the protein is not involved in the immune response. Homology to the Drosophila gene female sterile homeotic suggests that this human gene may be part of a signal transduction pathway involved in growth control.cite web | title = Entrez Gene: BRD2 bromodomain containing 2| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=6046| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Haynes SR, Dollard C, Winston F, "et al." |title=The bromodomain: a conserved sequence found in human, Drosophila and yeast proteins. |journal=Nucleic Acids Res. |volume=20 |issue= 10 |pages= 2603 |year= 1992 |pmid= 1350857 |doi=
*cite journal | author=Beck S, Hanson I, Kelly A, "et al." |title=A homologue of the Drosophila female sterile homeotic (fsh) gene in the class II region of the human MHC. |journal=DNA Seq. |volume=2 |issue= 4 |pages= 203–10 |year= 1992 |pmid= 1352711 |doi=
*cite journal | author=Okamoto N, Ando A, Kawai J, "et al." |title=Orientation of HLA-DNA gene and identification of a CpG island-associated gene adjacent to DNA in human major histocompatibility complex class II region. |journal=Hum. Immunol. |volume=32 |issue= 3 |pages= 221–8 |year= 1992 |pmid= 1663500 |doi=
*cite journal | author=Denis GV, Green MR |title=A novel, mitogen-activated nuclear kinase is related to a Drosophila developmental regulator. |journal=Genes Dev. |volume=10 |issue= 3 |pages= 261–71 |year= 1996 |pmid= 8595877 |doi=
*cite journal | author=Thorpe KL, Abdulla S, Kaufman J, "et al." |title=Phylogeny and structure of the RING3 gene. |journal=Immunogenetics |volume=44 |issue= 5 |pages= 391–6 |year= 1996 |pmid= 8781126 |doi=
*cite journal | author=Thorpe KL, Gorman P, Thomas C, "et al." |title=Chromosomal localization, gene structure and transcription pattern of the ORFX gene, a homologue of the MHC-linked RING3 gene. |journal=Gene |volume=200 |issue= 1-2 |pages= 177–83 |year= 1997 |pmid= 9373153 |doi=
*cite journal | author=Taniguchi Y, Matsuzaka Y, Fujimoto H, "et al." |title=Nucleotide sequence of the ring3 gene in the class II region of the mouse MHC and its abundant expression in testicular germ cells. |journal=Genomics |volume=51 |issue= 1 |pages= 114–23 |year= 1998 |pmid= 9693039 |doi= 10.1006/geno.1998.5262
*cite journal | author=Guo N, Faller DV, Denis GV |title=Activation-induced nuclear translocation of RING3. |journal=J. Cell. Sci. |volume=113 ( Pt 17) |issue= |pages= 3085–91 |year= 2000 |pmid= 10934046 |doi=
*cite journal | author=Denis GV, Vaziri C, Guo N, Faller DV |title=RING3 kinase transactivates promoters of cell cycle regulatory genes through E2F. |journal=Cell Growth Differ. |volume=11 |issue= 8 |pages= 417–24 |year= 2001 |pmid= 10965846 |doi=
*cite journal | author=BelAiba RS, Baril P, Chebloune Y, "et al." |title=Identification and cloning of an 85-kDa protein homologous to RING3 that is upregulated in proliferating endothelial cells. |journal=Eur. J. Biochem. |volume=268 |issue= 16 |pages= 4398–407 |year= 2001 |pmid= 11502199 |doi=
*cite journal | author=Crowley TE, Kaine EM, Yoshida M, "et al." |title=Reproductive cycle regulation of nuclear import, euchromatic localization, and association with components of Pol II mediator of a mammalian double-bromodomain protein. |journal=Mol. Endocrinol. |volume=16 |issue= 8 |pages= 1727–37 |year= 2003 |pmid= 12145330 |doi=
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Zhou M, Peng C, Nie XM, "et al." |title= [Expression of BRD7-interacting proteins,BRD2 and BRD3, in nasopharyngeal carcinoma tissues] |journal=Ai Zheng |volume=22 |issue= 2 |pages= 123–7 |year= 2003 |pmid= 12600283 |doi=
*cite journal | author=Pal DK, Evgrafov OV, Tabares P, "et al." |title=BRD2 (RING3) is a probable major susceptibility gene for common juvenile myoclonic epilepsy. |journal=Am. J. Hum. Genet. |volume=73 |issue= 2 |pages= 261–70 |year= 2003 |pmid= 12830434 |doi=
*cite journal | author=Mungall AJ, Palmer SA, Sims SK, "et al." |title=The DNA sequence and analysis of human chromosome 6. |journal=Nature |volume=425 |issue= 6960 |pages= 805–11 |year= 2003 |pmid= 14574404 |doi= 10.1038/nature02055
*cite journal | author=Ota T, Suzuki Y, Nishikawa T, "et al." |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285
*cite journal | author=Kanno T, Kanno Y, Siegel RM, "et al." |title=Selective recognition of acetylated histones by bromodomain proteins visualized in living cells. |journal=Mol. Cell |volume=13 |issue= 1 |pages= 33–43 |year= 2004 |pmid= 14731392 |doi=
*cite journal | author=Beausoleil SA, Jedrychowski M, Schwartz D, "et al." |title=Large-scale characterization of HeLa cell nuclear phosphoproteins. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=101 |issue= 33 |pages= 12130–5 |year= 2004 |pmid= 15302935 |doi= 10.1073/pnas.0404720101
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Benevolenskaya EV, Murray HL, Branton P, "et al." |title=Binding of pRB to the PHD protein RBP2 promotes cellular differentiation. |journal=Mol. Cell |volume=18 |issue= 6 |pages= 623–35 |year= 2005 |pmid= 15949438 |doi= 10.1016/j.molcel.2005.05.012

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