RPS3A

Ribosomal protein S3A, also known as RPS3A, is a human gene.cite web | title = Entrez Gene: RPS3A ribosomal protein S3A| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=6189| accessdate = ]

PBB_Summary
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summary_text = Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 40S subunit. The protein belongs to the S3AE family of ribosomal proteins. It is located in the cytoplasm. Disruption of the gene encoding rat ribosomal protein S3a, also named v-fos transformation effector protein, in v-fos-transformed rat cells results in reversion of the transformed phenotype. Transcript variants utilizing alternative transcription start sites have been described. This gene is co-transcribed with the U73A and U73B small nucleolar RNA genes, which are located in its fourth and third introns, respectively. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.cite web | title = Entrez Gene: RPS3A ribosomal protein S3A| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=6189| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Wool IG, Chan YL, Glück A |title=Structure and evolution of mammalian ribosomal proteins. |journal=Biochem. Cell Biol. |volume=73 |issue= 11-12 |pages= 933–47 |year= 1996 |pmid= 8722009 |doi=
*cite journal | author=Metspalu A, Rebane A, Hoth S, "et al." |title=Human ribosomal protein S3a: cloning of the cDNA and primary structure of the protein. |journal=Gene |volume=119 |issue= 2 |pages= 313–6 |year= 1992 |pmid= 1398113 |doi=
*cite journal | author=Kato S, Sekine S, Oh SW, "et al." |title=Construction of a human full-length cDNA bank. |journal=Gene |volume=150 |issue= 2 |pages= 243–50 |year= 1995 |pmid= 7821789 |doi=
*cite journal | author=Matoba R, Okubo K, Hori N, "et al." |title=The addition of 5'-coding information to a 3'-directed cDNA library improves analysis of gene expression. |journal=Gene |volume=146 |issue= 2 |pages= 199–207 |year= 1994 |pmid= 8076819 |doi=
*cite journal | author=Nolte D, Taimor G, Kalff-Suske M, Seifart KH |title=The human S3a ribosomal protein: sequence, location and cell-free transcription of the functional gene. |journal=Gene |volume=169 |issue= 2 |pages= 179–85 |year= 1996 |pmid= 8647443 |doi=
*cite journal | author=Vladimirov SN, Ivanov AV, Karpova GG, "et al." |title=Characterization of the human small-ribosomal-subunit proteins by N-terminal and internal sequencing, and mass spectrometry. |journal=Eur. J. Biochem. |volume=239 |issue= 1 |pages= 144–9 |year= 1996 |pmid= 8706699 |doi=
*cite journal | author=Kho CJ, Wang Y, Zarbl H |title=Effect of decreased fte-1 gene expression on protein synthesis, cell growth, and transformation. |journal=Cell Growth Differ. |volume=7 |issue= 9 |pages= 1157–66 |year= 1997 |pmid= 8877097 |doi=
*cite journal | author=Naora H, Takai I, Adachi M, Naora H |title=Altered cellular responses by varying expression of a ribosomal protein gene: sequential coordination of enhancement and suppression of ribosomal protein S3a gene expression induces apoptosis. |journal=J. Cell Biol. |volume=141 |issue= 3 |pages= 741–53 |year= 1998 |pmid= 9566973 |doi=
*cite journal | author=Rebane A, Tamme R, Laan M, "et al." |title=A novel snoRNA (U73) is encoded within the introns of the human and mouse ribosomal protein S3a genes. |journal=Gene |volume=210 |issue= 2 |pages= 255–63 |year= 1998 |pmid= 9573378 |doi=
*cite journal | author=Kenmochi N, Kawaguchi T, Rozen S, "et al." |title=A map of 75 human ribosomal protein genes. |journal=Genome Res. |volume=8 |issue= 5 |pages= 509–23 |year= 1998 |pmid= 9582194 |doi=
*cite journal | author=Cui K, Coutts M, Stahl J, Sytkowski AJ |title=Novel interaction between the transcription factor CHOP (GADD153) and the ribosomal protein FTE/S3a modulates erythropoiesis. |journal=J. Biol. Chem. |volume=275 |issue= 11 |pages= 7591–6 |year= 2000 |pmid= 10713066 |doi=
*cite journal | author=Song D, Sakamoto S, Taniguchi T |title=Inhibition of poly(ADP-ribose) polymerase activity by Bcl-2 in association with the ribosomal protein S3a. |journal=Biochemistry |volume=41 |issue= 3 |pages= 929–34 |year= 2002 |pmid= 11790116 |doi=
*cite journal | author=Andersen JS, Lyon CE, Fox AH, "et al." |title=Directed proteomic analysis of the human nucleolus. |journal=Curr. Biol. |volume=12 |issue= 1 |pages= 1–11 |year= 2002 |pmid= 11790298 |doi=
*cite journal | author=Jäkel S, Mingot JM, Schwarzmaier P, "et al." |title=Importins fulfil a dual function as nuclear import receptors and cytoplasmic chaperones for exposed basic domains. |journal=EMBO J. |volume=21 |issue= 3 |pages= 377–86 |year= 2002 |pmid= 11823430 |doi= 10.1093/emboj/21.3.377
*cite journal | author=Goodin JL, Rutherford CL |title=Characterization of human ribosomal S3a gene expression during adenosine 3':5' cyclic monophosphate induced neuroendocrine differentiation of LNCaP cells. Regulation of S3a gene expression in LNCaP. |journal=Mol. Biol. Rep. |volume=29 |issue= 3 |pages= 301–16 |year= 2003 |pmid= 12463423 |doi=
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Scherer SW, Cheung J, MacDonald JR, "et al." |title=Human chromosome 7: DNA sequence and biology. |journal=Science |volume=300 |issue= 5620 |pages= 767–72 |year= 2003 |pmid= 12690205 |doi= 10.1126/science.1083423
*cite journal | author=Reuter TY, Medhurst AL, Waisfisz Q, "et al." |title=Yeast two-hybrid screens imply involvement of Fanconi anemia proteins in transcription regulation, cell signaling, oxidative metabolism, and cellular transport. |journal=Exp. Cell Res. |volume=289 |issue= 2 |pages= 211–21 |year= 2003 |pmid= 14499622 |doi=
*cite journal | author=Bernhard OK, Cunningham AL, Sheil MM |title=Analysis of proteins copurifying with the CD4/lck complex using one-dimensional polyacrylamide gel electrophoresis and mass spectrometry: comparison with affinity-tag based protein detection and evaluation of different solubilization methods. |journal=J. Am. Soc. Mass Spectrom. |volume=15 |issue= 4 |pages= 558–67 |year= 2004 |pmid= 15047060 |doi= 10.1016/j.jasms.2003.12.006

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