IGF2BP1

Insulin-like growth factor 2 mRNA binding protein 1, also known as IGF2BP1, is a human gene.cite web | title = Entrez Gene: IGF2BP1 insulin-like growth factor 2 mRNA binding protein 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=10642| accessdate = ]

PBB_Summary
section_title =
summary_text = This gene encodes a member of the IGF-II mRNA-binding protein (IMP) family. The protein encoded by this gene contains four K homology domains and two RNA recognition motifs. It functions by binding to the 5' UTR of the insulin-like growth factor 2 (IGF2) mRNA and regulating IGF2 translation.cite web | title = Entrez Gene: IGF2BP1 insulin-like growth factor 2 mRNA binding protein 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=10642| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Yaniv K, Yisraeli JK |title=The involvement of a conserved family of RNA binding proteins in embryonic development and carcinogenesis. |journal=Gene |volume=287 |issue= 1-2 |pages= 49–54 |year= 2002 |pmid= 11992722 |doi=
*cite journal | author=Yisraeli JK |title=VICKZ proteins: a multi-talented family of regulatory RNA-binding proteins. |journal=Biol. Cell |volume=97 |issue= 1 |pages= 87–96 |year= 2005 |pmid= 15601260 |doi= 10.1042/BC20040151
*cite journal | author=Prokipcak RD, Herrick DJ, Ross J |title=Purification and properties of a protein that binds to the C-terminal coding region of human c-myc mRNA. |journal=J. Biol. Chem. |volume=269 |issue= 12 |pages= 9261–9 |year= 1994 |pmid= 8132663 |doi=
*cite journal | author=Doyle GA, Betz NA, Leeds PF, "et al." |title=The c-myc coding region determinant-binding protein: a member of a family of KH domain RNA-binding proteins. |journal=Nucleic Acids Res. |volume=26 |issue= 22 |pages= 5036–44 |year= 1999 |pmid= 9801297 |doi=
*cite journal | author=Nielsen J, Christiansen J, Lykke-Andersen J, "et al." |title=A family of insulin-like growth factor II mRNA-binding proteins represses translation in late development. |journal=Mol. Cell. Biol. |volume=19 |issue= 2 |pages= 1262–70 |year= 1999 |pmid= 9891060 |doi=
*cite journal | author=Runge S, Nielsen FC, Nielsen J, "et al." |title=H19 RNA binds four molecules of insulin-like growth factor II mRNA-binding protein. |journal=J. Biol. Chem. |volume=275 |issue= 38 |pages= 29562–9 |year= 2000 |pmid= 10875929 |doi= 10.1074/jbc.M001156200
*cite journal | author=Nielsen FC, Nielsen J, Kristensen MA, "et al." |title=Cytoplasmic trafficking of IGF-II mRNA-binding protein by conserved KH domains. |journal=J. Cell. Sci. |volume=115 |issue= Pt 10 |pages= 2087–97 |year= 2003 |pmid= 11973350 |doi=
*cite journal | author=Lemm I, Ross J |title=Regulation of c-myc mRNA decay by translational pausing in a coding region instability determinant. |journal=Mol. Cell. Biol. |volume=22 |issue= 12 |pages= 3959–69 |year= 2002 |pmid= 12024010 |doi=
*cite journal | author=Ioannidis P, Mahaira L, Papadopoulou A, "et al." |title=8q24 Copy number gains and expression of the c-myc mRNA stabilizing protein CRD-BP in primary breast carcinomas. |journal=Int. J. Cancer |volume=104 |issue= 1 |pages= 54–9 |year= 2003 |pmid= 12532419 |doi= 10.1002/ijc.10794
*cite journal | author=Nielsen J, Adolph SK, Rajpert-De Meyts E, "et al." |title=Nuclear transit of human zipcode-binding protein IMP1. |journal=Biochem. J. |volume=376 |issue= Pt 2 |pages= 383–91 |year= 2003 |pmid= 12921532 |doi= 10.1042/BJ20030943
*cite journal | author=Ota T, Suzuki Y, Nishikawa T, "et al." |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285
*cite journal | author=Gu L, Shigemasa K, Ohama K |title=Increased expression of IGF II mRNA-binding protein 1 mRNA is associated with an advanced clinical stage and poor prognosis in patients with ovarian cancer. |journal=Int. J. Oncol. |volume=24 |issue= 3 |pages= 671–8 |year= 2004 |pmid= 14767552 |doi=
*cite journal | author=Hansen TV, Hammer NA, Nielsen J, "et al." |title=Dwarfism and impaired gut development in insulin-like growth factor II mRNA-binding protein 1-deficient mice. |journal=Mol. Cell. Biol. |volume=24 |issue= 10 |pages= 4448–64 |year= 2004 |pmid= 15121863 |doi=
*cite journal | author=Ioannidis P, Kottaridi C, Dimitriadis E, "et al." |title=Expression of the RNA-binding protein CRD-BP in brain and non-small cell lung tumors. |journal=Cancer Lett. |volume=209 |issue= 2 |pages= 245–50 |year= 2004 |pmid= 15159028 |doi= 10.1016/j.canlet.2003.12.015
*cite journal | author=Rackham O, Brown CM |title=Visualization of RNA-protein interactions in living cells: FMRP and IMP1 interact on mRNAs. |journal=EMBO J. |volume=23 |issue= 16 |pages= 3346–55 |year= 2005 |pmid= 15282548 |doi= 10.1038/sj.emboj.7600341
*cite journal | author=Nielsen J, Kristensen MA, Willemoës M, "et al." |title=Sequential dimerization of human zipcode-binding protein IMP1 on RNA: a cooperative mechanism providing RNP stability. |journal=Nucleic Acids Res. |volume=32 |issue= 14 |pages= 4368–76 |year= 2004 |pmid= 15314207 |doi= 10.1093/nar/gkh754
*cite journal | author=Suzuki Y, Yamashita R, Shirota M, "et al." |title=Sequence comparison of human and mouse genes reveals a homologous block structure in the promoter regions. |journal=Genome Res. |volume=14 |issue= 9 |pages= 1711–8 |year= 2004 |pmid= 15342556 |doi= 10.1101/gr.2435604
*cite journal | author=Liao B, Patel M, Hu Y, "et al." |title=Targeted knockdown of the RNA-binding protein CRD-BP promotes cell proliferation via an insulin-like growth factor II-dependent pathway in human K562 leukemia cells. |journal=J. Biol. Chem. |volume=279 |issue= 47 |pages= 48716–24 |year= 2005 |pmid= 15355996 |doi= 10.1074/jbc.M405853200

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