CETN2

Centrin, EF-hand protein, 2, also known as CETN2, is a human gene.cite web | title = Entrez Gene: CETN2 centrin, EF-hand protein, 2| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=1069| accessdate = ]

PBB_Summary
section_title =
summary_text = Caltractin belongs to a family of calcium-binding proteins and is a structural component of the centrosome. The high level of conservation from algae to humans and its association with the centrosome suggested that caltractin plays a fundamental role in the structure and function of the microtubule-organizing center, possibly required for the proper duplication and segregation of the centrosome.cite web | title = Entrez Gene: CETN2 centrin, EF-hand protein, 2| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=1069| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Tanaka T, Okui K, Nakamura Y |title=Assignment of the human caltractin gene (CALT) to Xq28 by fluorescence in situ hybridization. |journal=Genomics |volume=24 |issue= 3 |pages= 609–10 |year= 1995 |pmid= 7713520 |doi=
*cite journal | author=Lee VD, Huang B |title=Molecular cloning and centrosomal localization of human caltractin. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=90 |issue= 23 |pages= 11039–43 |year= 1994 |pmid= 8248209 |doi=
*cite journal | author=Chatterjee A, Tanaka T, Parrish JE, Herman GE |title=Refined mapping of caltractin in human Xq28 and in the homologous region of the mouse X chromosome places the gene within the bare patches (Bpa) and striated (Str) critical regions. |journal=Mamm. Genome |volume=6 |issue= 11 |pages= 802–4 |year= 1996 |pmid= 8597638 |doi=
*cite journal | author=Wolfrum U, Salisbury JL |title=Expression of centrin isoforms in the mammalian retina. |journal=Exp. Cell Res. |volume=242 |issue= 1 |pages= 10–7 |year= 1998 |pmid= 9665797 |doi= 10.1006/excr.1998.4038
*cite journal | author=Durussel I, Blouquit Y, Middendorp S, "et al." |title=Cation- and peptide-binding properties of human centrin 2. |journal=FEBS Lett. |volume=472 |issue= 2-3 |pages= 208–12 |year= 2000 |pmid= 10788612 |doi=
*cite journal | author=Mallon AM, Platzer M, Bate R, "et al." |title=Comparative genome sequence analysis of the Bpa/Str region in mouse and Man. |journal=Genome Res. |volume=10 |issue= 6 |pages= 758–75 |year= 2000 |pmid= 10854409 |doi=
*cite journal | author=Hartley JL, Temple GF, Brasch MA |title=DNA cloning using in vitro site-specific recombination. |journal=Genome Res. |volume=10 |issue= 11 |pages= 1788–95 |year= 2001 |pmid= 11076863 |doi=
*cite journal | author=Simpson JC, Wellenreuther R, Poustka A, "et al." |title=Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing. |journal=EMBO Rep. |volume=1 |issue= 3 |pages= 287–92 |year= 2001 |pmid= 11256614 |doi= 10.1093/embo-reports/kvd058
*cite journal | author=Araki M, Masutani C, Takemura M, "et al." |title=Centrosome protein centrin 2/caltractin 1 is part of the xeroderma pigmentosum group C complex that initiates global genome nucleotide excision repair. |journal=J. Biol. Chem. |volume=276 |issue= 22 |pages= 18665–72 |year= 2001 |pmid= 11279143 |doi= 10.1074/jbc.M100855200
*cite journal | author=Salisbury JL, Suino KM, Busby R, Springett M |title=Centrin-2 is required for centriole duplication in mammalian cells. |journal=Curr. Biol. |volume=12 |issue= 15 |pages= 1287–92 |year= 2003 |pmid= 12176356 |doi=
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Matei E, Miron S, Blouquit Y, "et al." |title=C-terminal half of human centrin 2 behaves like a regulatory EF-hand domain. |journal=Biochemistry |volume=42 |issue= 6 |pages= 1439–50 |year= 2003 |pmid= 12578356 |doi= 10.1021/bi0269714
*cite journal | author=Gavet O, Alvarez C, Gaspar P, Bornens M |title=Centrin4p, a novel mammalian centrin specifically expressed in ciliated cells. |journal=Mol. Biol. Cell |volume=14 |issue= 5 |pages= 1818–34 |year= 2004 |pmid= 12802058 |doi= 10.1091/mbc.E02-11-0709
*cite journal | author=Popescu A, Miron S, Blouquit Y, "et al." |title=Xeroderma pigmentosum group C protein possesses a high affinity binding site to human centrin 2 and calmodulin. |journal=J. Biol. Chem. |volume=278 |issue= 41 |pages= 40252–61 |year= 2003 |pmid= 12890685 |doi= 10.1074/jbc.M302546200
*cite journal | author=Kilmartin JV |title=Sfi1p has conserved centrin-binding sites and an essential function in budding yeast spindle pole body duplication. |journal=J. Cell Biol. |volume=162 |issue= 7 |pages= 1211–21 |year= 2003 |pmid= 14504268 |doi= 10.1083/jcb.200307064
*cite journal | author=Chang F, Re F, Sebastian S, "et al." |title=HIV-1 Vpr induces defects in mitosis, cytokinesis, nuclear structure, and centrosomes. |journal=Mol. Biol. Cell |volume=15 |issue= 4 |pages= 1793–801 |year= 2004 |pmid= 14767062 |doi= 10.1091/mbc.E03-09-0691
*cite journal | author=Tourbez M, Firanescu C, Yang A, "et al." |title=Calcium-dependent self-assembly of human centrin 2. |journal=J. Biol. Chem. |volume=279 |issue= 46 |pages= 47672–80 |year= 2005 |pmid= 15356003 |doi= 10.1074/jbc.M404996200
*cite journal | author=Gerhard DS, Wagner L, Feingold EA, "et al." |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504
*cite journal | author=Wiemann S, Arlt D, Huber W, "et al." |title=From ORFeome to biology: a functional genomics pipeline. |journal=Genome Res. |volume=14 |issue= 10B |pages= 2136–44 |year= 2004 |pmid= 15489336 |doi= 10.1101/gr.2576704
*cite journal | author=Nishi R, Okuda Y, Watanabe E, "et al." |title=Centrin 2 stimulates nucleotide excision repair by interacting with xeroderma pigmentosum group C protein. |journal=Mol. Cell. Biol. |volume=25 |issue= 13 |pages= 5664–74 |year= 2005 |pmid= 15964821 |doi= 10.1128/MCB.25.13.5664-5674.2005

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