- Small nuclear ribonucleoprotein D2
Small nuclear ribonucleoprotein D2 polypeptide 16.5kDa, also known as SNRPD2, is a human
gene .cite web | title = Entrez Gene: SNRPD2 small nuclear ribonucleoprotein D2 polypeptide 16.5kDa| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=6633| accessdate = ]PBB_Summary
section_title =
summary_text = The protein encoded by this gene belongs to the small nuclear ribonucleoprotein core protein family. It is required for pre-mRNA splicing and small nuclear ribonucleoprotein biogenesis. Alternative splicing occurs at this locus and two transcript variants encoding the same protein have been identified.cite web | title = Entrez Gene: SNRPD2 small nuclear ribonucleoprotein D2 polypeptide 16.5kDa| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=6633| accessdate = ]References
Further reading
PBB_Further_reading
citations =
*cite journal | author=Lehmeier T, Foulaki K, Lührmann R |title=Evidence for three distinct D proteins, which react differentially with anti-Sm autoantibodies, in the cores of the major snRNPs U1, U2, U4/U6 and U5. |journal=Nucleic Acids Res. |volume=18 |issue= 22 |pages= 6475–84 |year= 1991 |pmid= 1701240 |doi=
*cite journal | author=Rokeach LA, Haselby JA, Hoch SO |title=Molecular cloning of a cDNA encoding the human Sm-D autoantigen. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=85 |issue= 13 |pages= 4832–6 |year= 1988 |pmid= 3260384 |doi=
*cite journal | author=Lehmeier T, Raker V, Hermann H, Lührmann R |title=cDNA cloning of the Sm proteins D2 and D3 from human small nuclear ribonucleoproteins: evidence for a direct D1-D2 interaction. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=91 |issue= 25 |pages= 12317–21 |year= 1995 |pmid= 7527560 |doi=
*cite journal | author=Liu Q, Fischer U, Wang F, Dreyfuss G |title=The spinal muscular atrophy disease gene product, SMN, and its associated protein SIP1 are in a complex with spliceosomal snRNP proteins. |journal=Cell |volume=90 |issue= 6 |pages= 1013–21 |year= 1997 |pmid= 9323129 |doi=
*cite journal | author=Fury MG, Zhang W, Christodoulopoulos I, Zieve GW |title=Multiple protein: protein interactions between the snRNP common core proteins. |journal=Exp. Cell Res. |volume=237 |issue= 1 |pages= 63–9 |year= 1998 |pmid= 9417867 |doi= 10.1006/excr.1997.3750
*cite journal | author=Kambach C, Walke S, Young R, "et al." |title=Crystal structures of two Sm protein complexes and their implications for the assembly of the spliceosomal snRNPs. |journal=Cell |volume=96 |issue= 3 |pages= 375–87 |year= 1999 |pmid= 10025403 |doi=
*cite journal | author=Charroux B, Pellizzoni L, Perkinson RA, "et al." |title=Gemin3: A novel DEAD box protein that interacts with SMN, the spinal muscular atrophy gene product, and is a component of gems. |journal=J. Cell Biol. |volume=147 |issue= 6 |pages= 1181–94 |year= 2000 |pmid= 10601333 |doi=
*cite journal | author=Charroux B, Pellizzoni L, Perkinson RA, "et al." |title=Gemin4. A novel component of the SMN complex that is found in both gems and nucleoli. |journal=J. Cell Biol. |volume=148 |issue= 6 |pages= 1177–86 |year= 2000 |pmid= 10725331 |doi=
*cite journal | author=Meister G, Bühler D, Laggerbauer B, "et al." |title=Characterization of a nuclear 20S complex containing the survival of motor neurons (SMN) protein and a specific subset of spliceosomal Sm proteins. |journal=Hum. Mol. Genet. |volume=9 |issue= 13 |pages= 1977–86 |year= 2000 |pmid= 10942426 |doi=
*cite journal | author=Ajuh P, Kuster B, Panov K, "et al." |title=Functional analysis of the human CDC5L complex and identification of its components by mass spectrometry. |journal=EMBO J. |volume=19 |issue= 23 |pages= 6569–81 |year= 2001 |pmid= 11101529 |doi= 10.1093/emboj/19.23.6569
*cite journal | author=Selenko P, Sprangers R, Stier G, "et al." |title=SMN tudor domain structure and its interaction with the Sm proteins. |journal=Nat. Struct. Biol. |volume=8 |issue= 1 |pages= 27–31 |year= 2001 |pmid= 11135666 |doi= 10.1038/83014
*cite journal | author=Urlaub H, Raker VA, Kostka S, Lührmann R |title=Sm protein-Sm site RNA interactions within the inner ring of the spliceosomal snRNP core structure. |journal=EMBO J. |volume=20 |issue= 1-2 |pages= 187–96 |year= 2001 |pmid= 11226169 |doi= 10.1093/emboj/20.1.187
*cite journal | author=Gubitz AK, Mourelatos Z, Abel L, "et al." |title=Gemin5, a novel WD repeat protein component of the SMN complex that binds Sm proteins. |journal=J. Biol. Chem. |volume=277 |issue= 7 |pages= 5631–6 |year= 2002 |pmid= 11714716 |doi= 10.1074/jbc.M109448200
*cite journal | author=Pellizzoni L, Baccon J, Rappsilber J, "et al." |title=Purification of native survival of motor neurons complexes and identification of Gemin6 as a novel component. |journal=J. Biol. Chem. |volume=277 |issue= 9 |pages= 7540–5 |year= 2002 |pmid= 11748230 |doi= 10.1074/jbc.M110141200
*cite journal | author=Friesen WJ, Wyce A, Paushkin S, "et al." |title=A novel WD repeat protein component of the methylosome binds Sm proteins. |journal=J. Biol. Chem. |volume=277 |issue= 10 |pages= 8243–7 |year= 2002 |pmid= 11756452 |doi= 10.1074/jbc.M109984200
*cite journal | author=Fong YW, Zhou Q |title=Stimulatory effect of splicing factors on transcriptional elongation. |journal=Nature |volume=414 |issue= 6866 |pages= 929–33 |year= 2002 |pmid= 11780068 |doi= 10.1038/414929a
*cite journal | author=Jurica MS, Licklider LJ, Gygi SR, "et al." |title=Purification and characterization of native spliceosomes suitable for three-dimensional structural analysis. |journal=RNA |volume=8 |issue= 4 |pages= 426–39 |year= 2002 |pmid= 11991638 |doi=
*cite journal | author=Baccon J, Pellizzoni L, Rappsilber J, "et al." |title=Identification and characterization of Gemin7, a novel component of the survival of motor neuron complex. |journal=J. Biol. Chem. |volume=277 |issue= 35 |pages= 31957–62 |year= 2002 |pmid= 12065586 |doi= 10.1074/jbc.M203478200
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Blagoev B, Kratchmarova I, Ong SE, "et al." |title=A proteomics strategy to elucidate functional protein-protein interactions applied to EGF signaling. |journal=Nat. Biotechnol. |volume=21 |issue= 3 |pages= 315–8 |year= 2003 |pmid= 12577067 |doi= 10.1038/nbt790PBB_Controls
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