SNTA1

Syntrophin, alpha 1 (dystrophin-associated protein A1, 59kDa, acidic component), also known as SNTA1, is a human gene.cite web | title = Entrez Gene: SNTA1 syntrophin, alpha 1 (dystrophin-associated protein A1, 59kDa, acidic component)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=6640| accessdate = ]

PBB_Summary
section_title =
summary_text = Dystrophin is a large, rod-like cytoskeletal protein found at the inner surface of muscle fibers. Dystrophin is missing in Duchenne Muscular Dystrophy patients and is present in reduced amounts in Becker Muscular Dystrophy patients. The protein encoded by this gene is a peripheral membrane protein found associated with dystrophin and dystrophin-related proteins. This gene is a member of the syntrophin gene family, which contains at least two other structurally-related genes.cite web | title = Entrez Gene: SNTA1 syntrophin, alpha 1 (dystrophin-associated protein A1, 59kDa, acidic component)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=6640| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Miyagoe-Suzuki Y, Takeda SI |title=Association of neuronal nitric oxide synthase (nNOS) with alpha1-syntrophin at the sarcolemma. |journal=Microsc. Res. Tech. |volume=55 |issue= 3 |pages= 164–70 |year= 2002 |pmid= 11747091 |doi= 10.1002/jemt.1167
*cite journal | author=Blake DJ |title=Dystrobrevin dynamics in muscle-cell signalling: a possible target for therapeutic intervention in Duchenne muscular dystrophy? |journal=Neuromuscul. Disord. |volume=12 Suppl 1 |issue= |pages= S110–7 |year= 2002 |pmid= 12206805 |doi=
*cite journal | author=Yang B, Jung D, Rafael JA, "et al." |title=Identification of alpha-syntrophin binding to syntrophin triplet, dystrophin, and utrophin. |journal=J. Biol. Chem. |volume=270 |issue= 10 |pages= 4975–8 |year= 1995 |pmid= 7890602 |doi=
*cite journal | author=Ahn AH, Freener CA, Gussoni E, "et al." |title=The three human syntrophin genes are expressed in diverse tissues, have distinct chromosomal locations, and each bind to dystrophin and its relatives. |journal=J. Biol. Chem. |volume=271 |issue= 5 |pages= 2724–30 |year= 1996 |pmid= 8576247 |doi=
*cite journal | author=Castelló A, Brochériou V, Chafey P, "et al." |title=Characterization of the dystrophin-syntrophin interaction using the two-hybrid system in yeast. |journal=FEBS Lett. |volume=383 |issue= 1-2 |pages= 124–8 |year= 1996 |pmid= 8612778 |doi=
*cite journal | author=Gee SH, Madhavan R, Levinson SR, "et al." |title=Interaction of muscle and brain sodium channels with multiple members of the syntrophin family of dystrophin-associated proteins. |journal=J. Neurosci. |volume=18 |issue= 1 |pages= 128–37 |year= 1998 |pmid= 9412493 |doi=
*cite journal | author=Iwata Y, Pan Y, Yoshida T, "et al." |title=Alpha1-syntrophin has distinct binding sites for actin and calmodulin. |journal=FEBS Lett. |volume=423 |issue= 2 |pages= 173–7 |year= 1998 |pmid= 9512352 |doi=
*cite journal | author=Hasegawa M, Cuenda A, Spillantini MG, "et al." |title=Stress-activated protein kinase-3 interacts with the PDZ domain of alpha1-syntrophin. A mechanism for specific substrate recognition. |journal=J. Biol. Chem. |volume=274 |issue= 18 |pages= 12626–31 |year= 1999 |pmid= 10212242 |doi=
*cite journal | author=Hillier BJ, Christopherson KS, Prehoda KE, "et al." |title=Unexpected modes of PDZ domain scaffolding revealed by structure of nNOS-syntrophin complex. |journal=Science |volume=284 |issue= 5415 |pages= 812–5 |year= 1999 |pmid= 10221915 |doi=
*cite journal | author=Fernández-Larrea J, Merlos-Suárez A, Ureña JM, "et al." |title=A role for a PDZ protein in the early secretory pathway for the targeting of proTGF-alpha to the cell surface. |journal=Mol. Cell |volume=3 |issue= 4 |pages= 423–33 |year= 1999 |pmid= 10230395 |doi=
*cite journal | author=Lumeng C, Phelps S, Crawford GE, "et al." |title=Interactions between beta 2-syntrophin and a family of microtubule-associated serine/threonine kinases. |journal=Nat. Neurosci. |volume=2 |issue= 7 |pages= 611–7 |year= 1999 |pmid= 10404183 |doi= 10.1038/10165
*cite journal | author=Adams ME, Kramarcy N, Krall SP, "et al." |title=Absence of alpha-syntrophin leads to structurally aberrant neuromuscular synapses deficient in utrophin. |journal=J. Cell Biol. |volume=150 |issue= 6 |pages= 1385–98 |year= 2000 |pmid= 10995443 |doi=
*cite journal | author=Newey SE, Benson MA, Ponting CP, "et al." |title=Alternative splicing of dystrobrevin regulates the stoichiometry of syntrophin binding to the dystrophin protein complex. |journal=Curr. Biol. |volume=10 |issue= 20 |pages= 1295–8 |year= 2001 |pmid= 11069112 |doi=
*cite journal | author=Olalla L, Aledo JC, Bannenberg G, Márquez J |title=The C-terminus of human glutaminase L mediates association with PDZ domain-containing proteins. |journal=FEBS Lett. |volume=488 |issue= 3 |pages= 116–22 |year= 2001 |pmid= 11163757 |doi=
*cite journal | author=Marchand S, Stetzkowski-Marden F, Cartaud J |title=Differential targeting of components of the dystrophin complex to the postsynaptic membrane. |journal=Eur. J. Neurosci. |volume=13 |issue= 2 |pages= 221–9 |year= 2001 |pmid= 11168526 |doi=
*cite journal | author=Xu H, Goldfarb M |title=Multiple effector domains within SNT1 coordinate ERK activation and neuronal differentiation of PC12 cells. |journal=J. Biol. Chem. |volume=276 |issue= 16 |pages= 13049–56 |year= 2001 |pmid= 11278583 |doi= 10.1074/jbc.M009925200
*cite journal | author=Hogan A, Shepherd L, Chabot J, "et al." |title=Interaction of gamma 1-syntrophin with diacylglycerol kinase-zeta. Regulation of nuclear localization by PDZ interactions. |journal=J. Biol. Chem. |volume=276 |issue= 28 |pages= 26526–33 |year= 2001 |pmid= 11352924 |doi= 10.1074/jbc.M104156200
*cite journal | author=Oak SA, Russo K, Petrucci TC, Jarrett HW |title=Mouse alpha1-syntrophin binding to Grb2: further evidence of a role for syntrophin in cell signaling. |journal=Biochemistry |volume=40 |issue= 37 |pages= 11270–8 |year= 2001 |pmid= 11551227 |doi=
*cite journal | author=Adams ME, Mueller HA, Froehner SC |title=In vivo requirement of the alpha-syntrophin PDZ domain for the sarcolemmal localization of nNOS and aquaporin-4. |journal=J. Cell Biol. |volume=155 |issue= 1 |pages= 113–22 |year= 2001 |pmid= 11571312 |doi= 10.1083/jcb.200106158
*cite journal | author=Neely JD, Amiry-Moghaddam M, Ottersen OP, "et al." |title=Syntrophin-dependent expression and localization of Aquaporin-4 water channel protein. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=98 |issue= 24 |pages= 14108–13 |year= 2002 |pmid= 11717465 |doi= 10.1073/pnas.241508198

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