PSIP1

PSIP1

PC4 and SFRS1 interacting protein 1, also known as PSIP1, is a human gene.cite web | title = Entrez Gene: PSIP1 PC4 and SFRS1 interacting protein 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=11168| accessdate = ] It is thought to impede the replication of HIV.

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References

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*cite journal | author=Van Maele B, Debyser Z |title=HIV-1 integration: an interplay between HIV-1 integrase, cellular and viral proteins. |journal=AIDS reviews |volume=7 |issue= 1 |pages= 26–43 |year= 2005 |pmid= 15875659 |doi=
*cite journal | author=Van Maele B, Busschots K, Vandekerckhove L, "et al." |title=Cellular co-factors of HIV-1 integration. |journal=Trends Biochem. Sci. |volume=31 |issue= 2 |pages= 98–105 |year= 2006 |pmid= 16403635 |doi= 10.1016/j.tibs.2005.12.002
*cite journal | author=Freed EO, Mouland AJ |title=The cell biology of HIV-1 and other retroviruses. |journal=Retrovirology |volume=3 |issue= |pages= 77 |year= 2006 |pmid= 17083721 |doi= 10.1186/1742-4690-3-77
*cite journal | author=Ge H, Si Y, Roeder RG |title=Isolation of cDNAs encoding novel transcription coactivators p52 and p75 reveals an alternate regulatory mechanism of transcriptional activation. |journal=EMBO J. |volume=17 |issue= 22 |pages= 6723–9 |year= 1999 |pmid= 9822615 |doi= 10.1093/emboj/17.22.6723
*cite journal | author=Ge H, Si Y, Wolffe AP |title=A novel transcriptional coactivator, p52, functionally interacts with the essential splicing factor ASF/SF2. |journal=Mol. Cell |volume=2 |issue= 6 |pages= 751–9 |year= 1999 |pmid= 9885563 |doi=
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*cite journal | author=Singh DP, Kimura A, Chylack LT, Shinohara T |title=Lens epithelium-derived growth factor (LEDGF/p75) and p52 are derived from a single gene by alternative splicing. |journal=Gene |volume=242 |issue= 1-2 |pages= 265–73 |year= 2000 |pmid= 10721720 |doi=
*cite journal | author=Ochs RL, Muro Y, Si Y, "et al." |title=Autoantibodies to DFS 70 kd/transcription coactivator p75 in atopic dermatitis and other conditions. |journal=J. Allergy Clin. Immunol. |volume=105 |issue= 6 Pt 1 |pages= 1211–20 |year= 2000 |pmid= 10856157 |doi=
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*cite journal | author=Wu X, Daniels T, Molinaro C, "et al." |title=Caspase cleavage of the nuclear autoantigen LEDGF/p75 abrogates its pro-survival function: implications for autoimmunity in atopic disorders. |journal=Cell Death Differ. |volume=9 |issue= 9 |pages= 915–25 |year= 2003 |pmid= 12181742 |doi= 10.1038/sj.cdd.4401063
*cite journal | author=Cherepanov P, Maertens G, Proost P, "et al." |title=HIV-1 integrase forms stable tetramers and associates with LEDGF/p75 protein in human cells. |journal=J. Biol. Chem. |volume=278 |issue= 1 |pages= 372–81 |year= 2003 |pmid= 12407101 |doi= 10.1074/jbc.M209278200
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Maertens G, Cherepanov P, Pluymers W, "et al." |title=LEDGF/p75 is essential for nuclear and chromosomal targeting of HIV-1 integrase in human cells. |journal=J. Biol. Chem. |volume=278 |issue= 35 |pages= 33528–39 |year= 2003 |pmid= 12796494 |doi= 10.1074/jbc.M303594200
*cite journal | author=Maertens G, Cherepanov P, Debyser Z, "et al." |title=Identification and characterization of a functional nuclear localization signal in the HIV-1 integrase interactor LEDGF/p75. |journal=J. Biol. Chem. |volume=279 |issue= 32 |pages= 33421–9 |year= 2004 |pmid= 15163664 |doi= 10.1074/jbc.M404700200
*cite journal | author=Beausoleil SA, Jedrychowski M, Schwartz D, "et al." |title=Large-scale characterization of HeLa cell nuclear phosphoproteins. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=101 |issue= 33 |pages= 12130–5 |year= 2004 |pmid= 15302935 |doi= 10.1073/pnas.0404720101
*cite journal | author=Llano M, Vanegas M, Fregoso O, "et al." |title=LEDGF/p75 determines cellular trafficking of diverse lentiviral but not murine oncoretroviral integrase proteins and is a component of functional lentiviral preintegration complexes. |journal=J. Virol. |volume=78 |issue= 17 |pages= 9524–37 |year= 2004 |pmid= 15308744 |doi= 10.1128/JVI.78.17.9524-9537.2004
*cite journal | author=Cherepanov P, Devroe E, Silver PA, Engelman A |title=Identification of an evolutionarily conserved domain in human lens epithelium-derived growth factor/transcriptional co-activator p75 (LEDGF/p75) that binds HIV-1 integrase. |journal=J. Biol. Chem. |volume=279 |issue= 47 |pages= 48883–92 |year= 2005 |pmid= 15371438 |doi= 10.1074/jbc.M406307200
*cite journal | author=Llano M, Delgado S, Vanegas M, Poeschla EM |title=Lens epithelium-derived growth factor/p75 prevents proteasomal degradation of HIV-1 integrase. |journal=J. Biol. Chem. |volume=279 |issue= 53 |pages= 55570–7 |year= 2005 |pmid= 15475359 |doi= 10.1074/jbc.M408508200
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