RALA

V-ral simian leukemia viral oncogene homolog A (ras related), also known as RALA, is a human gene.cite web | title = Entrez Gene: RALA v-ral simian leukemia viral oncogene homolog A (ras related)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=5898| accessdate = ]

PBB_Summary
section_title =
summary_text = The product of this gene belongs to the small GTPase superfamily, Ras family of proteins. GTP-binding proteins mediate the transmembrane signaling initiated by the occupancy of certain cell surface receptors. This gene encodes a low molecular mass ras-like GTP-binding protein that shares about 50% similarity with other ras proteins.cite web | title = Entrez Gene: RALA v-ral simian leukemia viral oncogene homolog A (ras related)| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=5898| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Kinsella BT, Erdman RA, Maltese WA |title=Carboxyl-terminal isoprenylation of ras-related GTP-binding proteins encoded by rac1, rac2, and ralA. |journal=J. Biol. Chem. |volume=266 |issue= 15 |pages= 9786–94 |year= 1991 |pmid= 1903399 |doi=
*cite journal | author=Polakis PG, Weber RF, Nevins B, "et al." |title=Identification of the ral and rac1 gene products, low molecular mass GTP-binding proteins from human platelets. |journal=J. Biol. Chem. |volume=264 |issue= 28 |pages= 16383–9 |year= 1989 |pmid= 2550440 |doi=
*cite journal | author=Chardin P, Tavitian A |title=Coding sequences of human ralA and ralB cDNAs. |journal=Nucleic Acids Res. |volume=17 |issue= 11 |pages= 4380 |year= 1989 |pmid= 2662142 |doi=
*cite journal | author=Rousseau-Merck MF, Bernheim A, Chardin P, "et al." |title=The ras-related ral gene maps to chromosome 7p15-22. |journal=Hum. Genet. |volume=79 |issue= 2 |pages= 132–6 |year= 1988 |pmid= 3292391 |doi=
*cite journal | author=Cantor SB, Urano T, Feig LA |title=Identification and characterization of Ral-binding protein 1, a potential downstream target of Ral GTPases. |journal=Mol. Cell. Biol. |volume=15 |issue= 8 |pages= 4578–84 |year= 1995 |pmid= 7623849 |doi=
*cite journal | author=Jullien-Flores V, Dorseuil O, Romero F, "et al." |title=Bridging Ral GTPase to Rho pathways. RLIP76, a Ral effector with CDC42/Rac GTPase-activating protein activity. |journal=J. Biol. Chem. |volume=270 |issue= 38 |pages= 22473–7 |year= 1995 |pmid= 7673236 |doi=
*cite journal | author=Wang KL, Khan MT, Roufogalis BD |title=Identification and characterization of a calmodulin-binding domain in Ral-A, a Ras-related GTP-binding protein purified from human erythrocyte membrane. |journal=J. Biol. Chem. |volume=272 |issue= 25 |pages= 16002–9 |year= 1997 |pmid= 9188503 |doi=
*cite journal | author=Luo JQ, Liu X, Hammond SM, "et al." |title=RalA interacts directly with the Arf-responsive, PIP2-dependent phospholipase D1. |journal=Biochem. Biophys. Res. Commun. |volume=235 |issue= 3 |pages= 854–9 |year= 1997 |pmid= 9207251 |doi= 10.1006/bbrc.1997.6793
*cite journal | author=Ikeda M, Ishida O, Hinoi T, "et al." |title=Identification and characterization of a novel protein interacting with Ral-binding protein 1, a putative effector protein of Ral. |journal=J. Biol. Chem. |volume=273 |issue= 2 |pages= 814–21 |year= 1998 |pmid= 9422736 |doi=
*cite journal | author=Vavvas D, Li X, Avruch J, Zhang XF |title=Identification of Nore1 as a potential Ras effector. |journal=J. Biol. Chem. |volume=273 |issue= 10 |pages= 5439–42 |year= 1998 |pmid= 9488663 |doi=
*cite journal | author=Kim JH, Lee SD, Han JM, "et al." |title=Activation of phospholipase D1 by direct interaction with ADP-ribosylation factor 1 and RalA. |journal=FEBS Lett. |volume=430 |issue= 3 |pages= 231–5 |year= 1998 |pmid= 9688545 |doi=
*cite journal | author=Ohta Y, Suzuki N, Nakamura S, "et al." |title=The small GTPase RalA targets filamin to induce filopodia. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=96 |issue= 5 |pages= 2122–8 |year= 1999 |pmid= 10051605 |doi=
*cite journal | author=Wang KL, Roufogalis BD |title=Ca2+/calmodulin stimulates GTP binding to the ras-related protein ral-A. |journal=J. Biol. Chem. |volume=274 |issue= 21 |pages= 14525–8 |year= 1999 |pmid= 10329639 |doi=
*cite journal | author=Suzuki J, Yamazaki Y, Li G, "et al." |title=Involvement of Ras and Ral in chemotactic migration of skeletal myoblasts. |journal=Mol. Cell. Biol. |volume=20 |issue= 13 |pages= 4658–65 |year= 2000 |pmid= 10848592 |doi=
*cite journal | author=de Bruyn KM, de Rooij J, Wolthuis RM, "et al." |title=RalGEF2, a pleckstrin homology domain containing guanine nucleotide exchange factor for Ral. |journal=J. Biol. Chem. |volume=275 |issue= 38 |pages= 29761–6 |year= 2000 |pmid= 10889189 |doi= 10.1074/jbc.M001160200
*cite journal | author=Brymora A, Valova VA, Larsen MR, "et al." |title=The brain exocyst complex interacts with RalA in a GTP-dependent manner: identification of a novel mammalian Sec3 gene and a second Sec15 gene. |journal=J. Biol. Chem. |volume=276 |issue= 32 |pages= 29792–7 |year= 2001 |pmid= 11406615 |doi= 10.1074/jbc.C100320200
*cite journal | author=Sugihara K, Asano S, Tanaka K, "et al." |title=The exocyst complex binds the small GTPase RalA to mediate filopodia formation. |journal=Nat. Cell Biol. |volume=4 |issue= 1 |pages= 73–8 |year= 2002 |pmid= 11744922 |doi= 10.1038/ncb720
*cite journal | author=Clough RR, Sidhu RS, Bhullar RP |title=Calmodulin binds RalA and RalB and is required for the thrombin-induced activation of Ral in human platelets. |journal=J. Biol. Chem. |volume=277 |issue= 32 |pages= 28972–80 |year= 2002 |pmid= 12034722 |doi= 10.1074/jbc.M201504200
*cite journal | author=Strausberg RL, Feingold EA, Grouse LH, "et al." |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899
*cite journal | author=Xu L, Frankel P, Jackson D, "et al." |title=Elevated phospholipase D activity in H-Ras- but not K-Ras-transformed cells by the synergistic action of RalA and ARF6. |journal=Mol. Cell. Biol. |volume=23 |issue= 2 |pages= 645–54 |year= 2003 |pmid= 12509462 |doi=

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