HIST2H2BE

Histone cluster 2, H2be, also known as HIST2H2BE, is a human gene.cite web | title = Entrez Gene: HIST2H2BE histone cluster 2, H2be| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=8349| accessdate = ]

PBB_Summary
section_title =
summary_text = Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene encodes a member of the histone H2B family, and generates two transcripts through the use of the conserved stem-loop termination motif, and the polyA addition motif.cite web | title = Entrez Gene: HIST2H2BE histone cluster 2, H2be| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=8349| accessdate = ]

References

Further reading

PBB_Further_reading
citations =
*cite journal | author=Collart D, Romain PL, Huebner K, "et al." |title=A human histone H2B.1 variant gene, located on chromosome 1, utilizes alternative 3' end processing. |journal=J. Cell. Biochem. |volume=50 |issue= 4 |pages= 374–85 |year= 1993 |pmid= 1469070 |doi= 10.1002/jcb.240500406
*cite journal | author=Collart D, Ramsey-Ewing A, Bortell R, "et al." |title=Isolation and characterization of a cDNA from a human histone H2B gene which is reciprocally expressed in relation to replication-dependent H2B histone genes during HL60 cell differentiation. |journal=Biochemistry |volume=30 |issue= 6 |pages= 1610–7 |year= 1991 |pmid= 1993178 |doi=
*cite journal | author=Jackson S, Brooks W, Jackson V |title=Dynamics of the interactions of histones H2A,H2B and H3,H4 with torsionally stressed DNA. |journal=Biochemistry |volume=33 |issue= 18 |pages= 5392–403 |year= 1994 |pmid= 8180162 |doi=
*cite journal | author=Frohm M, Gunne H, Bergman AC, "et al." |title=Biochemical and antibacterial analysis of human wound and blister fluid. |journal=Eur. J. Biochem. |volume=237 |issue= 1 |pages= 86–92 |year= 1996 |pmid= 8620898 |doi=
*cite journal | author=Rodriguez P, Munroe D, Prawitt D, "et al." |title=Functional characterization of human nucleosome assembly protein-2 (NAP1L4) suggests a role as a histone chaperone. |journal=Genomics |volume=44 |issue= 3 |pages= 253–65 |year= 1997 |pmid= 9325046 |doi= 10.1006/geno.1997.4868
*cite journal | author=El Kharroubi A, Piras G, Zensen R, Martin MA |title=Transcriptional activation of the integrated chromatin-associated human immunodeficiency virus type 1 promoter. |journal=Mol. Cell. Biol. |volume=18 |issue= 5 |pages= 2535–44 |year= 1998 |pmid= 9566873 |doi=
*cite journal | author=Zhang Y, Sun ZW, Iratni R, "et al." |title=SAP30, a novel protein conserved between human and yeast, is a component of a histone deacetylase complex. |journal=Mol. Cell |volume=1 |issue= 7 |pages= 1021–31 |year= 1998 |pmid= 9651585 |doi=
*cite journal | author=Lorain S, Quivy JP, Monier-Gavelle F, "et al." |title=Core histones and HIRIP3, a novel histone-binding protein, directly interact with WD repeat protein HIRA. |journal=Mol. Cell. Biol. |volume=18 |issue= 9 |pages= 5546–56 |year= 1998 |pmid= 9710638 |doi=
*cite journal | author=Khan IU, Wallin R, Gupta RS, Kammer GM |title=Protein kinase A-catalyzed phosphorylation of heat shock protein 60 chaperone regulates its attachment to histone 2B in the T lymphocyte plasma membrane. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=95 |issue= 18 |pages= 10425–30 |year= 1998 |pmid= 9724719 |doi=
*cite journal | author=Becker W, Weber Y, Wetzel K, "et al." |title=Sequence characteristics, subcellular localization, and substrate specificity of DYRK-related kinases, a novel family of dual specificity protein kinases. |journal=J. Biol. Chem. |volume=273 |issue= 40 |pages= 25893–902 |year= 1998 |pmid= 9748265 |doi=
*cite journal | author=Allen MP, Zeng C, Schneider K, "et al." |title=Growth arrest-specific gene 6 (Gas6)/adhesion related kinase (Ark) signaling promotes gonadotropin-releasing hormone neuronal survival via extracellular signal-regulated kinase (ERK) and Akt. |journal=Mol. Endocrinol. |volume=13 |issue= 2 |pages= 191–201 |year= 1999 |pmid= 9973250 |doi=
*cite journal | author=Piredda L, Farrace MG, Lo Bello M, "et al." |title=Identification of 'tissue' transglutaminase binding proteins in neural cells committed to apoptosis. |journal=FASEB J. |volume=13 |issue= 2 |pages= 355–64 |year= 1999 |pmid= 9973324 |doi=
*cite journal | author=Carrier F, Georgel PT, Pourquier P, "et al." |title=Gadd45, a p53-responsive stress protein, modifies DNA accessibility on damaged chromatin. |journal=Mol. Cell. Biol. |volume=19 |issue= 3 |pages= 1673–85 |year= 1999 |pmid= 10022855 |doi=
*cite journal | author=Kawasaki H, Schiltz L, Chiu R, "et al." |title=ATF-2 has intrinsic histone acetyltransferase activity which is modulated by phosphorylation. |journal=Nature |volume=405 |issue= 6783 |pages= 195–200 |year= 2000 |pmid= 10821277 |doi= 10.1038/35012097
*cite journal | author=Deng L, de la Fuente C, Fu P, "et al." |title=Acetylation of HIV-1 Tat by CBP/P300 increases transcription of integrated HIV-1 genome and enhances binding to core histones. |journal=Virology |volume=277 |issue= 2 |pages= 278–95 |year= 2001 |pmid= 11080476 |doi= 10.1006/viro.2000.0593
*cite journal | author=Baake M, Doenecke D, Albig W |title=Characterisation of nuclear localisation signals of the four human core histones. |journal=J. Cell. Biochem. |volume=81 |issue= 2 |pages= 333–46 |year= 2001 |pmid= 11241673 |doi=
*cite journal | author=Chadwick BP, Willard HF |title=A novel chromatin protein, distantly related to histone H2A, is largely excluded from the inactive X chromosome. |journal=J. Cell Biol. |volume=152 |issue= 2 |pages= 375–84 |year= 2001 |pmid= 11266453 |doi=
*cite journal | author=Freire J, Covelo G, Sarandeses C, "et al." |title=Identification of nuclear-import and cell-cycle regulatory proteins that bind to prothymosin alpha. |journal=Biochem. Cell Biol. |volume=79 |issue= 2 |pages= 123–31 |year= 2001 |pmid= 11310559 |doi=
*cite journal | author=Nemergut ME, Mizzen CA, Stukenberg T, "et al." |title=Chromatin docking and exchange activity enhancement of RCC1 by histones H2A and H2B. |journal=Science |volume=292 |issue= 5521 |pages= 1540–3 |year= 2001 |pmid= 11375490 |doi= 10.1126/science.292.5521.1540
*cite journal | author=Deng L, Wang D, de la Fuente C, "et al." |title=Enhancement of the p300 HAT activity by HIV-1 Tat on chromatin DNA. |journal=Virology |volume=289 |issue= 2 |pages= 312–26 |year= 2001 |pmid= 11689053 |doi= 10.1006/viro.2001.1129

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